Anaphylaxis is defined as an acute, life-threatening, systemic allergic reaction associated with a broad array of clinical manifestations. Anaphylaxis typically is a type 1 (IgE mediated) hypersensitivity reaction though other mechanism may also be involved. Patients most commonly present with cutaneous symptoms followed by respiratory and gastrointestinal symptoms. Prompt recognition and treatment can be life saving. Epinephrine is the drug of choice for treatment of anaphylaxis. It is imperative that patients and their caregivers are educated on the use of epinephrine autoinjectors and provided with an emergency action plan for managing anaphylaxis.
Citation: Divya Seth, Deepak Kamat. Anaphylaxis: recognition, treatment, and outcomes[J]. AIMS Medical Science, 2022, 9(1): 65-80. doi: 10.3934/medsci.2022007
Anaphylaxis is defined as an acute, life-threatening, systemic allergic reaction associated with a broad array of clinical manifestations. Anaphylaxis typically is a type 1 (IgE mediated) hypersensitivity reaction though other mechanism may also be involved. Patients most commonly present with cutaneous symptoms followed by respiratory and gastrointestinal symptoms. Prompt recognition and treatment can be life saving. Epinephrine is the drug of choice for treatment of anaphylaxis. It is imperative that patients and their caregivers are educated on the use of epinephrine autoinjectors and provided with an emergency action plan for managing anaphylaxis.
American Academy of Allergy, Asthma, and Immunology
Angiotensin converting enzyme
Auto-injectable epinephrine
Blood pressure
Calcitonin gene-related peptide
Computerized tomography
Electroencephalogram
Exercise induced anaphylaxis
Electrocardiogram
Emergency room
Hereditary angioedema
Health care professional
Immunoglobulin
Mast cell tryptase
Non-steroidal anti-inflammatory drugs
Platelet Activating Factor
Radio-contrast media
Tumor necrosis factor
United States
United States Pharmacopeia
Ultra-violet
Vocal Cord Dysfunction
World Allergy Organization
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