Bacterial resistance caused by prolonged administration of the same antibiotics exacerbates the threat of bacterial infection to human health. It is essential to optimize antibiotic treatment measures. In this paper, we formulate a simplified model of conversion between sensitive and resistant bacteria. Subsequently, impulsive state feedback control is introduced to reduce bacterial resistance to a low level. The global asymptotic stability of the positive equilibrium and the orbital stability of the order-1 periodic solution are proved by the Poincaré-Bendixson Theorem and the theory of the semi-continuous dynamical system, respectively. Finally, numerical simulations are performed to validate the accuracy of the theoretical findings.
Citation: Xiaoxiao Yan, Zhong Zhao, Yuanxian Hui, Jingen Yang. Dynamic analysis of a bacterial resistance model with impulsive state feedback control[J]. Mathematical Biosciences and Engineering, 2023, 20(12): 20422-20436. doi: 10.3934/mbe.2023903
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Bacterial resistance caused by prolonged administration of the same antibiotics exacerbates the threat of bacterial infection to human health. It is essential to optimize antibiotic treatment measures. In this paper, we formulate a simplified model of conversion between sensitive and resistant bacteria. Subsequently, impulsive state feedback control is introduced to reduce bacterial resistance to a low level. The global asymptotic stability of the positive equilibrium and the orbital stability of the order-1 periodic solution are proved by the Poincaré-Bendixson Theorem and the theory of the semi-continuous dynamical system, respectively. Finally, numerical simulations are performed to validate the accuracy of the theoretical findings.
The key to solving the general quadratic congruence equation is to solve the equation of the form x2≡amodp, where a and p are integers, p>0 and p is not divisible by a. For relatively large p, it is impractical to use the Euler criterion to distinguish whether the integer a with (a,p)=1 is quadratic residue of modulo p. In order to study this issue, Legendre has proposed a new tool-Legendre's symbol.
Let p be an odd prime, the quadratic character modulo p is called the Legendre's symbol, which is defined as follows:
(ap)={1, if a is a quadratic residue modulo p;−1, if a is a quadratic non-residue modulo p;0, if p∣a. |
The Legendre's symbol makes it easy for us to calculate the level of quadratic residues. The basic properties of Legendre's symbol can be found in any book on elementary number theory, such as [1,2,3].
The properties of Legendre's symbol and quadratic residues play an important role in number theory. Many scholars have studied them and achieved some important results. For examples, see the [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21].
One of the most representative properties of the Legendre's symbol is the quadratic reciprocal law:
Let p and q be two distinct odd primes. Then, (see Theorem 9.8 in [1] or Theorems 4–6 in [3])
(pq)⋅(qp)=(−1)(p−1)(q−1)4. |
For any odd prime p with p≡1mod4 there exist two non-zero integers α(p) and β(p) such that
p=α2(p)+β2(p). | (1) |
In fact, the integers α(p) and β(p) in the (1) can be expressed in terms of Legendre's symbol modulo p (see Theorems 4–11 in [3])
α(p)=12p−1∑a=1(a3+ap)andβ(p)=12p−1∑a=1(a3+rap), |
where r is any integer, and (r,p)=1, (rp)=−1, (∗p)=χ2 denote the Legendre's symbol modulo p.
Noting that Legendre's symbol is a special kind of character. For research on character, Han [7] studied the sum of a special character χ(ma+ˉa), for any integer m with (m,p)=1, then
|p−1∑a=1χ(ma+ˉa)|2=2p+(mp)p−1∑a=1χ(a)p−1∑b=1(b(b−1)(a2b−1)p), |
which is a special case of a general polynomial character sums ∑N+Ma=N+1χ(f(a)), where M and N are any positive integers, and f(x) is a polynomial.
In [8], Du and Li introduced a special character sums C(χ,m,n,c;p) in the following form:
C(χ,m,n,c;p)=p−1∑a=0p−1∑b=0χ(a2+na−b2−nb+c)⋅e(mb2−ma2p), |
and studied the asymptotic properties of it. They obtained
p−1∑c=1|C(χ,m,n,c;p)|2k={p2k+1+k2−3k−22⋅p2k+O(p2k−1),ifχ is the Legendre symbol modulo p;p2k+1+k2−3k−22⋅p2k+O(p2k−1/2),ifχ is a complex character modulo p. |
Recently, Yuan and Zhang [12] researched the question about the estimation of the mean value of high-powers for a special character sum modulo a prime, let p be an odd prime with p≡1mod6, then for any integer k≥0, they have the identity
Sk(p)=13⋅[dk+(−d+9b2)k+(−d−9b2)k], |
where
Sk(p)=1p−1p−1∑r=1Ak(r), |
A(r)=1+p−1∑a=1(a2+rˉap), |
and for any integer r with (r,p)=1.
More relevant research on special character sums will not be repeated. Inspired by these papers, we have the question: If we replace the special character sums with Legendre's symbol, can we get good results on p≡1mod4?
We will convert β(p) to another form based on the properties of complete residues
β(p)=12p−1∑a=1(a+nˉap), |
where ˉa is the inverse of a modulo p. That is, ˉa satisfy the equation x⋅a≡1modp for any integer a with (a,p)=1.
For any integer k≥0, G(n) and Kk(p) are defined as follows:
G(n)=1+p−1∑a=1(a2+nˉa2p)andKk(p)=1p−1p−1∑n=1Gk(n). |
In this paper, we will use the analytic methods and properties of the classical Gauss sums and Dirichlet character sums to study the computational problem of Kk(p) for any positive integer k, and give a linear recurrence formulas for Kk(p). That is, we will prove the following result.
Theorem 1. Let p be an odd prime with p≡1mod4, then we have
Kk(p)=(4p+2)⋅Kk−2(p)−8(2α2−p)⋅Kk−3(p)+(16α4−16pα2+4p−1)⋅Kk−4(p), |
for all integer k≥4 with
K0(p)=1,K1(p)=0,K2(p)=2p+1,K3(p)=−3(4α2−2p), |
where
α=α(p)=p−12∑a=1(a+ˉap). |
Applying the properties of the linear recurrence sequence, we may immediately deduce the following corollaries.
Corollary 1. Let p be an odd prime with p≡1mod4. Then we have
1p−1p−1∑n=111+∑p−1a=1(a2+nˉa2p)=16α2p−28α2−8p2+14p16α4−16α2p+4p−1. |
Corollary 2. Let p be an odd prime with p≡1mod4. Then we have
1p−1p−1∑n=1p−1∑m=0(1+p−1∑a=1(a2+nˉa2p))⋅e(nm2p)=−√p. |
Corollary 3. Let p be an odd prime with p≡1mod4. Then we have
1p−1p−1∑n=1p−1∑m=0[1+p−1∑a=1(a2+nˉa2p)]2⋅e(nm2p)=(4α2−2p)⋅√p. |
Corollary 4. Let p be an odd prime with p≡1mod8. Then we have
p−1∑n=1(1+p−1∑a=1(a2+nˉa2p))⋅p−1∑m=0e(nm4p)=√p(−1+B(1))−p, |
where
B(1)=p−1∑m=0e(m4p). |
If we consider such a sequence Fk(p) as follows: Let p be a prime with p≡1mod8, χ4 be any fourth-order character modulo p. For any integer k≥0, we define the Fk(p) as
Fk(p)=p−1∑n=11Gk(n), |
we have
Fk(p)=116α4−16α2p+4p−1Fk−4(p)−(4p+2)16α4−16α2p+4p−1Fk−2(p)+4(4α2−2p)16α4−16α2p+4p−1Fk−1(p). |
Lemma 1. Let p be an odd prime with p≡1mod4. Then for any fourth-order character χ4modp, we have the identity
τ2(χ4)+τ2(¯χ4)=2√p⋅α, |
where
τ(χ4)=p−1∑a=1χ4(a)e(ap) |
denotes the classical Gauss sums, e(y)=e2πiy,i2=−1, and α is the same as in the Theorem 1.
Proof. See Lemma 2.2 in [9].
Lemma 2. Let p be an odd prime. Then for any non-principal character ψ modulo p, we have the identity
τ(ψ2)=ψ2(2)τ(χ2)⋅τ(ψ)⋅τ(ψχ2), |
where χ2=(∗p) denotes the Legendre's symbol modulo p.
Proof. See Lemma 2 in [12].
Lemma 3. Let p be a prime with p≡1mod4, then for any integer n with (n,p)=1 and fourth-order character χ4modp, we have the identity
p−1∑a=1(a2+nˉa2p)=−1−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4)). |
Proof. For any integer a with (a,p)=1, we have the identity
1+χ4(a)+χ2(a)+¯χ4(a)=4, |
if a satisfies a≡b4modp for some integer b with (b,p)=1 and
1+χ4(a)+χ2(a)+¯χ4(a)=0, |
otherwise. So from these and the properties of Gauss sums we have
p−1∑a=1(a2+nˉa2p)=p−1∑a=1(a2p)(a4+np)=p−1∑a=1χ2(a4)χ2(a4+n)=p−1∑a=1(1+χ4(a)+χ2(a)+¯χ4(a))⋅χ2(a)⋅χ2(a+n)=p−1∑a=1(1+χ4(na)+χ2(na)+¯χ4(na))⋅χ2(na)⋅χ2(na+n)=p−1∑a=1χ2(a)χ2(a+1)+p−1∑a=1χ4(na)χ2(a)χ2(a+1) | (2) |
+p−1∑a=1χ2(na)χ2(a)χ2(a+1)+p−1∑a=1¯χ4(na)χ2(a)χ2(a+1)=p−1∑a=1χ2(1+ˉa)+p−1∑a=1χ4(na)χ2(a)χ2(a+1)+p−1∑a=1χ2(n)χ2(a+1)+p−1∑a=1¯χ4(na)χ2(a)χ2(a+1). |
Noting that for any non-principal character χ,
p−1∑a=1χ(a)=0 |
and
p−1∑a=1χ(a)χ(a+1)=1τ(ˉχ)p−1∑b=1p−1∑a=1ˉχ(b)χ(a)e(b(a+1)p). |
Then we have
p−1∑a=1χ2(1+ˉa)=−1,p−1∑a=1χ2(a+1)=−1, |
p−1∑a=1χ4(a)χ2(a)χ2(a+1)=1τ(χ2)p−1∑b=1p−1∑a=1χ2(b)χ4(a)χ2(a)e(b(a+1)p)=1τ(χ2)p−1∑b=1¯χ4(b)e(bp)p−1∑a=1χ4(ab)χ2(ab)e(abp) | (3) |
=1τ(χ2)⋅τ(¯χ4)⋅τ(χ4χ2). |
For any non-principal character ψ, from Lemma 2 we have
τ(ψ2)=ψ2(2)τ(χ2)⋅τ(ψ)⋅τ(ψχ2). | (4) |
Taking ψ=χ4, note that
τ(χ2)=√p, τ(χ4)⋅τ(¯χ4)=χ4(−1)⋅p, |
from (3) and (4), we have
p−1∑a=1χ4(a)χ2(a)χ2(a+1)=¯χ42(2)⋅τ(χ24)⋅τ(χ2)⋅τ(¯χ4)τ(χ2)⋅τ(χ4)=χ2(2)⋅τ(χ2)⋅τ2(¯χ4)τ(χ4)⋅τ(¯χ4)=χ2(2)⋅√p⋅τ2(¯χ4)χ4(−1)⋅p | (5) |
=χ2(2)⋅τ2(¯χ4)χ4(−1)⋅√p. |
Similarly, we also have
p−1∑a=1¯χ4(a)χ2(a)χ2(a+1)=χ2(2)⋅τ2(χ4)χ4(−1)⋅√p. | (6) |
Consider the quadratic character modulo p, we have
(2p)=χ2(2)={1,if p≡±1mod8;−1,if p≡±3mod8. | (7) |
And when p≡1mod8, we have χ4(−1)=1; when p≡5mod8, we have χ4(−1)=−1. Combining (2) and (5)–(7) we can deduce that
p−1∑a=1(a2+nˉa2p)=−1−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4)). |
This prove Lemma 3.
Lemma 4. Let p be an odd prime with p≡1mod4. Then for any integer k≥4 and n with (n,p)=1, we have the fourth-order linear recurrence formula
Gk(n)=(4p+2)⋅Gk−2(n)+8(p−2α2)⋅Gk−3(n)+[(4α2−2p)2−(2p−1)2]⋅Gk−4(n), |
where
α=α(p)=12p−1∑a=1(a3+ap)=p−12∑a=1(a+ˉap), |
(∗p)=χ2 denotes the Legendre's symbol.
Proof. For p≡1mod4, any integer n with (n,p)=1, and fourth-order character χ4 modulo p, we have the identity
χ44(n)=¯χ44(n)=χ0(n), χ24(n)=χ2(n), |
where χ0 denotes the principal character modulo p.
According to Lemma 3,
p−1∑a=1(a2+nˉa2p)=−1−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4)), |
G(n)=1+p−1∑a=1(a2+nˉa2p). |
We have
G(n)=−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4)), | (8) |
G2(n)=[−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4))]2=1−2χ2(n)⋅1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4))+1p⋅(χ2(n)⋅τ4(¯χ4)+χ2(n)⋅τ4(χ4)+2p2)=1−2χ2(n)⋅1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4))+1p⋅(χ2(n)⋅(τ4(¯χ4)+τ4(χ4))+2p2). |
According to Lemma 1, we have
(τ2(χ4)+τ2(¯χ4))2=τ4(¯χ4)+τ4(χ4)+2p2=4pα2. |
Therefore, we may immediately deduce
G2(n)=1−2(χ2(n)⋅(G(n)+χ2(n))+1p(χ2(n)⋅(τ4(¯χ4)+τ4(χ4))+2p2)=1−2χ2(n)⋅(G(n)+χ2(n)) | (9) |
+1p⋅[χ2(n)((τ2(¯χ4)+τ2(χ4))2−2p2)+2p2]=2p−1−2χ2(n)⋅G(n)+(4α2−2p)⋅χ2(n), |
G3(n)=[−χ2(n)+1√p⋅(χ4(n)⋅τ2(¯χ4)+¯χ4(n)⋅τ2(χ4))]3=(2p−1−2χ2(n)⋅G(n)+(4α2−2p)⋅χ2(n))⋅G(n) | (10) |
=(4α2−2p)χ2(n)⋅G(n)+(2p+3)G(n)−(4p−2)χ2(n)−2(4α2−2p) |
and
[G2(n)−(2p−1)]2=[χ2(n)⋅(4α2−2p)−2χ2(n)⋅G(n)]2, |
which implies that
G4(n)=(4p+2)⋅G2(n)+8(p−2α2)⋅G(n)+[(4α2−2p)2−(2p−1)2]. | (11) |
So for any integer k≥4, from (8)–(11), we have the fourth-order linear recurrence formula
Gk(n)=Gk−4(n)⋅G4(n)=(4p+2)⋅Gk−2(n)+8(p−2α2)⋅Gk−3(n)+[(4α2−2p)2−(2p−1)2]⋅Gk−4(n). |
This proves Lemma 4.
In this section, we will complete the proof of our theorem.
Let p be any prime with p≡1mod4, then we have
K0(p)=1p−1p−1∑n=1G0(n)=p−1p−1=1. | (12) |
K1(p)=1p−1p−1∑n=1G1(n)=1p−1p−1∑n=1(−χ2(n)+1√p⋅(χ4(n)τ2(¯χ4)+¯χ4(n)τ2(χ4)))=0, | (13) |
K2(p)=1p−1p−1∑n=1G2(n)=1p−1p−1∑n=1(−χ2(n)+1√p⋅(χ4(n)τ2(¯χ4)+¯χ4(n)τ2(χ4)))2=2p+1, | (14) |
K3(p)=1p−1p−1∑n=1G3(n)=1p−1p−1∑n=1(−χ2(n)+1√p⋅(χ4(n)τ2(¯χ4)+¯χ4(n)τ2(χ4)))3=−3(4α2−2p). | (15) |
It is clear that from Lemma 4, if k≥4, we have
Kk(p)=1p−1p−1∑n=1Gk(n)=(4p+2)⋅Kk−2(p)−8(2α2−p)⋅Kk−3(p)+(16α4−16pα2+4p−1)⋅Kk−4(p). | (16) |
Now Theorem 1 follows (12)–(16). Obviously, using Theorem 1 to all negative integers, and that lead to Corollary 1.
This completes the proofs of our all results.
Some notes:
Note 1: In our theorem, know n is an integer, and (n,p)=1. According to the properties of quadratic residual, χ2(n)=±1, χ4(n)=±1.
Note 2: In our theorem, we only discussed the case p≡1mod8. If p≡3mod4, then the result is trivial. In fact, in this case, for any integer n with (n,p)=1, we have the identity
G(n)=1+p−1∑a=1(a2+nˉa2p)=1+p−1∑a=1(a4p)⋅(a4+np)=1+p−1∑a=1(ap)⋅(a+np)=1+p−1∑a=1(a2+nap)=1+p−1∑a=1(1+nˉap)=p−1∑a=0(1+nap)=0. |
Thus, for all prime p with p≡3mod4 and k≥1, we have Kk(p)=0.
The main result of this paper is Theorem 1. It gives an interesting computational formula for Kk(p) with p≡1mod4. That is, for any integer k, we have the identity
Kk(p)=(4p+2)⋅Kk−2(p)−8(2α2−p)⋅Kk−3(p)+(16α4−16pα2+4p−1)⋅Kk−4(p). |
Thus, the problems of calculating a linear recurrence formula of one kind special character sums modulo a prime are given.
The authors declare they have not used Artificial Intelligence (AI) tools in the creation of this article.
The authors are grateful to the anonymous referee for very helpful and detailed comments.
This work is supported by the N.S.F. (11971381, 12371007) of China and Shaanxi Fundamental Science Research Project for Mathematics and Physics (22JSY007).
The authors declare no conflicts of interest.
[1] |
K. Ababneh, I. E. Alkhazali, The impact of antibiotic abuse: Health and economic burden, Biomed. J. Sci. Tech. Res., 16 (2019), 11794–11797. https://doi.org/10.26717/BJSTR.2019.16.002802 doi: 10.26717/BJSTR.2019.16.002802
![]() |
[2] |
D. J. Austin, R. M. Anderson, Studies of antibiotic resistance within the patient, hospitals and the community using simple mathematical models, Philos. Trans. R. Soc., B, 354 (1999), 721–738. http://doi.org/10.1098/rstb.1999.0425 doi: 10.1098/rstb.1999.0425
![]() |
[3] |
J. M. A. Blair, M. A. Webber, A. J. Baylay, D. O. Ogbolu, L. J. V. Piddock, Molecular mechanisms of antibiotic resistance, Nat. Rev. Microbiol., 13 (2015), 42–51. https://doi.org/10.1038/nrmicro3380 doi: 10.1038/nrmicro3380
![]() |
[4] |
J. J. Dong, J. D. Russo, K. Sampson, Population dynamics model and analysis for bacteria transformation and conjugation, J. Phys. Commun., 4 (2020), 095021. https://doi.org/10.1088/2399-6528/abb8be doi: 10.1088/2399-6528/abb8be
![]() |
[5] |
T. Stalder, L. M. Rogers, C. Renfrow, H. Yano, Z. Smith, E. M. Top, Emerging patterns of plasmid-host coevolution that stabilize antibiotic resistance, Sci. Rep., 7 (2017), 4853. https://doi.org/10.1038/s41598-017-04662-0 doi: 10.1038/s41598-017-04662-0
![]() |
[6] |
E. Ibargüen-Mondragón, J. P. Romero-Leiton, L. Esteva, M. C. Gómez, S. P. Hidalgo-Bonilla, Stability and periodic solutions for a model of bacterial resistance to antibiotics caused by mutations and plasmids, Appl. Math. Modell., 76 (2019), 238–251. https://doi.org/10.1016/j.apm.2019.06.017 doi: 10.1016/j.apm.2019.06.017
![]() |
[7] |
E. Ibargüen-Mondragón, S. Mosquera, M. Cerón, E. M. Burbano-Rosero, Sandra P. Hidalgo-Bonilla, L. Esteva, et al., Mathematical modeling on bacterial resistance to multiple antibiotics caused by spontaneous mutations, Biosystems, 117 (2014), 60–67. https://doi.org/10.1016/j.biosystems.2014.01.005 doi: 10.1016/j.biosystems.2014.01.005
![]() |
[8] |
B. Daşbaşı, İ. Öztürk, Mathematical modelling of bacterial resistance to multiple antibiotics and immune system response, SpringerPlus, 5 (2016), 1–17. https://doi.org/10.1186/s40064-016-2017-8 doi: 10.1186/s40064-016-2017-8
![]() |
[9] |
X. Hou, B. Liu, L. Wang, Z. Zhao, Complex dynamics in a Filippov pest control model with group defense, Int. J. Biomath., 15 (2022), 2250053. https://doi.org/10.1142/S179352452250053X doi: 10.1142/S179352452250053X
![]() |
[10] |
A. M. Garber, Antibiotic exposure and resistance in mixed bacterial populations, Theor. Popul. Biol., 32 (1987), 326–346. https://doi.org/10.1016/0040-5809(87)90053-0 doi: 10.1016/0040-5809(87)90053-0
![]() |
[11] |
Z. Zhao, F. Tao, Q. Li, Dynamic analysis of conversion from a drug-sensitivity strain to a drug-resistant strain, Int. J. Biomath., 11 (2018), 1850113. https://doi.org/10.1142/S1793524518501139 doi: 10.1142/S1793524518501139
![]() |
[12] |
J. Jia, Y. Zhao, Z. Zhao, B. Liu, X. Song, Y. Hui, Dynamics of a within-host drug resistance model with impulsive state feedback control, Math. Biosci. Eng., 20 (2023), 2219–2231. https://doi.org/10.3934/mbe.2023103 doi: 10.3934/mbe.2023103
![]() |
[13] |
E. Massad, M. N. Burattini, F. A. B. Coutinho, An optimization model for antibiotic use, Appl. Math. Comput., 201 (2008), 161–167. https://doi.org/10.1016/j.amc.2007.12.007 doi: 10.1016/j.amc.2007.12.007
![]() |
[14] |
E. Ibargüen-Mondragón, L. Esteva, M. C. Gómez, An optimal control problem applied to plasmid-mediated antibiotic resistance, J. Appl. Math. Comput., 68 (2022), 1635–1667. https://doi.org/10.1007/s12190-021-01583-0 doi: 10.1007/s12190-021-01583-0
![]() |
[15] | W. Lv, L. Liu, S. J. Zhuang, Dynamics and optimal control in transmission of tungiasis diseases. Int. J. Biomath., 15 (2022), 2150076. https://doi.org/10.1142/S1793524521500765 |
[16] |
J. Xu, S. Yuan, T. Zhang, Optimal harvesting of a fuzzy water hyacinth-fish model with Kuznets curve effect, Int. J. Biomath., 16 (2023), 2250082. https://doi.org/10.1142/S1793524522500826 doi: 10.1142/S1793524522500826
![]() |
[17] |
M. Bodzioch, P. Bajger, U. Foryś, Competition between populations: preventing domination of resistant population using optimal control, Appl. Math. Modell., 114 (2023), 671–693. https://doi.org/10.1016/j.apm.2022.10.016 doi: 10.1016/j.apm.2022.10.016
![]() |
[18] |
G. Rigatos, M. Abbaszadeh, G. Cuccurullo, A nonlinear optimal control method against the spreading of epidemics, Int. J. Biomath., 15 (2022), 2250026. https://doi.org/10.1142/S1793524522500267 doi: 10.1142/S1793524522500267
![]() |
[19] |
Q. Liu, L. Huang, L. Chen, A pest management model with state feedback control, Adv. Differ. Equations, 2016 (2016), 1–11. https://doi.org/10.1186/s13662-016-0985-1 doi: 10.1186/s13662-016-0985-1
![]() |
[20] |
M. Zhang, G. Song, L. Chen, A state feedback impulse model for computer worm control, Nonlinear Dyn., 85 (2016), 1561–1569. https://doi.org/10.1007/s11071-016-2779-0 doi: 10.1007/s11071-016-2779-0
![]() |
[21] |
B. Liu, Y. Tian, B. Kang, Dynamics on a holling II predator-prey model with state-dependent impulsive control, Int. J. Biomath., 5 (2012), 1260006. https://doi.org/10.1142/S1793524512600066 doi: 10.1142/S1793524512600066
![]() |
[22] |
H. Li, Y. Tian, Dynamic behavior analysis of a feedback control predator-prey model with exponential fear effect and Hassell-Varley functional response, J. Franklin Inst., 360 (2023), 3479–3498. https://doi.org/10.1016/j.jfranklin.2022.11.030 doi: 10.1016/j.jfranklin.2022.11.030
![]() |
[23] |
P. Feketa, V. Klinshov, L. Lücken, A survey on the modeling of hybrid behaviors: How to account for impulsive jumps properly, Commun. Nonlinear Sci. Numer. Simul., 103 (2021), 105955. https://doi.org/10.1016/j.cnsns.2021.105955 doi: 10.1016/j.cnsns.2021.105955
![]() |
[24] |
M. Huang, L. Chen, X. Song, Stability of a convex order one periodic solution of unilateral asymptotic type, Nonlinear Dyn., 90 (2017), 83–93. https://doi.org/10.1007/s11071-017-3647-2 doi: 10.1007/s11071-017-3647-2
![]() |
[25] |
L. Chen, X. Liang, Y. Pei, The periodic solutions of the impulsive state feedback dynamical system, Commun. Math. Biol. Neurosci., 2018 (2018), 14–29. https://doi.org/10.28919/cmbn/3754 doi: 10.28919/cmbn/3754
![]() |
[26] |
Y. Tian, Y. Gao, K. Sun, A fishery predator-prey model with anti-predator behavior and complex dynamics induced by weighted fishing strategies, Math. Biosci. Eng., 20 (2023), 1558–1579. https://doi.org/10.3934/mbe.2023071 doi: 10.3934/mbe.2023071
![]() |
[27] |
S. Dashkovskiy, P. Feketa, Input-to-state stability of impulsive systems and their networks, Nonlinear Anal.: Hybrid Syst., 26 (2017), 190–200. https://doi.org/10.1016/j.nahs.2017.06.004 doi: 10.1016/j.nahs.2017.06.004
![]() |
[28] |
J. P. Hespanha, D. Liberzon, A. R. Teel, Lyapunov conditions for input-to-state stability of impulsive systems, Automatica, 44 (2008), 2735–2744. https://doi.org/10.1016/j.automatica.2008.03.021 doi: 10.1016/j.automatica.2008.03.021
![]() |
[29] |
C. Briat, A. Seuret, Robust stability of impulsive systems: A functional-based approach, IFAC Proc. Vol., 45 (2012), 412–417. https://doi.org/10.3182/20120606-3-NL-3011.00064 doi: 10.3182/20120606-3-NL-3011.00064
![]() |
[30] |
Y. Tian, Y. Gao, K. Sun, Qualitative analysis of exponential power rate fishery model and complex dynamics guided by a discontinuous weighted fishing strategy, Commun. Nonlinear Sci. Numer. Simul., 118 (2023), 107011. https://doi.org/10.1016/j.cnsns.2022.107011 doi: 10.1016/j.cnsns.2022.107011
![]() |
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