The aim of this work is to investigate the dynamics of a neural network, in which neurons, individually described by the FitzHugh-Nagumo model, are coupled by a generalized diffusive term. The formulation we are going to exploit is based on the general framework of graph theory.With the aim of defining the connection structure among the excitable elements, the discrete Laplacian matrix plays a fundamental role. In fact, it allows us to model the instantaneous propagation of signals between neurons, which need not be physically close to each other.
This approach enables us to address three fundamental issues. Firstly, each neuron is described using the well-known FitzHugh-Nagumo model which might allow to differentiate their individual behaviour. Furthermore, exploiting the Laplacian matrix, a well defined connection structure is formalized. Finally, random networks and an ensemble of excitatory and inhibitory synapses are considered.
Several simulations are performed to graphically present how dynamics within a network evolve. Thanks to an appropriate initial stimulus a wave is created: it propagates in a self-sustained way through the whole set of neurons. A novel graphical representation of the dynamics is shown.
Citation: Anna Cattani. FitzHugh-Nagumo equations with generalized diffusive coupling[J]. Mathematical Biosciences and Engineering, 2014, 11(2): 203-215. doi: 10.3934/mbe.2014.11.203
Related Papers:
[1] |
F. Berezovskaya, Erika Camacho, Stephen Wirkus, Georgy Karev .
"Traveling wave'' solutions of Fitzhugh model with cross-diffusion. Mathematical Biosciences and Engineering, 2008, 5(2): 239-260.
doi: 10.3934/mbe.2008.5.239
|
[2] |
Ryotaro Tsuneki, Shinji Doi, Junko Inoue .
Generation of slow phase-locked oscillation and variability of the interspike intervals in globally coupled neuronal oscillators. Mathematical Biosciences and Engineering, 2014, 11(1): 125-138.
doi: 10.3934/mbe.2014.11.125
|
[3] |
Robert Artebrant, Aslak Tveito, Glenn T. Lines .
A method for analyzing the stability of the resting state for a model of
pacemaker cells surrounded by stable cells. Mathematical Biosciences and Engineering, 2010, 7(3): 505-526.
doi: 10.3934/mbe.2010.7.505
|
[4] |
Bogdan Kazmierczak, Zbigniew Peradzynski .
Calcium waves with mechano-chemical couplings. Mathematical Biosciences and Engineering, 2013, 10(3): 743-759.
doi: 10.3934/mbe.2013.10.743
|
[5] |
Xixia Ma, Rongsong Liu, Liming Cai .
Stability of traveling wave solutions for a nonlocal Lotka-Volterra model. Mathematical Biosciences and Engineering, 2024, 21(1): 444-473.
doi: 10.3934/mbe.2024020
|
[6] |
Alan Dyson .
Traveling wave solutions to a neural field model with oscillatory synaptic coupling types. Mathematical Biosciences and Engineering, 2019, 16(2): 727-758.
doi: 10.3934/mbe.2019035
|
[7] |
Tong Li, Zhi-An Wang .
Traveling wave solutions of a singular Keller-Segel system with logistic source. Mathematical Biosciences and Engineering, 2022, 19(8): 8107-8131.
doi: 10.3934/mbe.2022379
|
[8] |
Tiberiu Harko, Man Kwong Mak .
Travelling wave solutions of the reaction-diffusion mathematical model of glioblastoma growth: An Abel equation based approach. Mathematical Biosciences and Engineering, 2015, 12(1): 41-69.
doi: 10.3934/mbe.2015.12.41
|
[9] |
Christopher E. Elmer .
The stability of stationary fronts for a discrete nerve axon model. Mathematical Biosciences and Engineering, 2007, 4(1): 113-129.
doi: 10.3934/mbe.2007.4.113
|
[10] |
Maryam Basiri, Frithjof Lutscher, Abbas Moameni .
Traveling waves in a free boundary problem for the spread of ecosystem engineers. Mathematical Biosciences and Engineering, 2025, 22(1): 152-184.
doi: 10.3934/mbe.2025008
|
Abstract
The aim of this work is to investigate the dynamics of a neural network, in which neurons, individually described by the FitzHugh-Nagumo model, are coupled by a generalized diffusive term. The formulation we are going to exploit is based on the general framework of graph theory.With the aim of defining the connection structure among the excitable elements, the discrete Laplacian matrix plays a fundamental role. In fact, it allows us to model the instantaneous propagation of signals between neurons, which need not be physically close to each other.
This approach enables us to address three fundamental issues. Firstly, each neuron is described using the well-known FitzHugh-Nagumo model which might allow to differentiate their individual behaviour. Furthermore, exploiting the Laplacian matrix, a well defined connection structure is formalized. Finally, random networks and an ensemble of excitatory and inhibitory synapses are considered.
Several simulations are performed to graphically present how dynamics within a network evolve. Thanks to an appropriate initial stimulus a wave is created: it propagates in a self-sustained way through the whole set of neurons. A novel graphical representation of the dynamics is shown.
References
[1]
|
Linear Algebra Appl., 436 (2012), 99-111.
|
[2]
|
Phys. Rev. E (3), 436 (2012), 99-111.
|
[3]
|
Ph.D thesis, Politecnico di Torino, ongoing.
|
[4]
|
Biophysical Journal, 1 (1961), 445-466.
|
[5]
|
J. Physiol., 117 (1952), 500-544.
|
[6]
|
third edition, Springer-Verlag, New York, 2002.
|
[7]
|
Progress of Theoretical Physics Supplements, 161 (2006), 389-392.
|
[8]
|
Review of Modern Physics, 47 (1975), 487-533.
|