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Mathematical Biosciences and Engineering

2007, Volume 4, Issue 4: 609-615. doi: 10.3934/mbe.2007.4.609
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Improved integrate-and-fire model for RSA

  • 1.
    Istituto di Biofisica, CNR, Via G. Moruzzi 1, 56124 - Pisa
  • 2.
    Istituto di Fisiologia Clinica, CNR, Via G. Moruzzi 1, 56124 - Pisa
  • Received: 01 November 2006 Accepted: 29 June 2018 Published: 01 August 2007

  • MSC : Primary: 92B05, 60G55; Secondary: 92C30.

  • A simple operational model of heart rate variability is described, accounting in particular for the respiratory sinus arrhythmia, and is fitted to some interbeat interval sequences recorded from normal subjects at rest. The model performance is evaluated using a test based on the nonlinear prediction approach. Moreover, a short comparative account of two similar models described in the literature is given.

    Citation: Michele Barbi, Angelo Di Garbo, Rita Balocchi. Improved integrate-and-fire model for RSA[J]. Mathematical Biosciences and Engineering, 2007, 4(4): 609-615. doi: 10.3934/mbe.2007.4.609

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  • A simple operational model of heart rate variability is described, accounting in particular for the respiratory sinus arrhythmia, and is fitted to some interbeat interval sequences recorded from normal subjects at rest. The model performance is evaluated using a test based on the nonlinear prediction approach. Moreover, a short comparative account of two similar models described in the literature is given.


  • This article has been cited by:

    1. Alona Ben-Tal, Sophie S. Shamailov, Julian F.R. Paton, Central regulation of heart rate and the appearance of respiratory sinus arrhythmia: New insights from mathematical modeling, 2014, 255, 00255564, 71, 10.1016/j.mbs.2014.06.015
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  • © 2007 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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