The role of excitatory interneurons (EINs) in the cortical has received increasing attention in the discussion of absence seizures. Numerous physiological experiments have confirmed the correlation between EIN and absence seizures. However, the dynamic mechanisms underlying this relationship are not well understood, and there are some challenges in selecting appropriate stimulation strategies for pyramidal clusters. In this study, we incorporated EIN into the previous Taylor model and developed an improved thalamocortical coupled model consisting of ten neuronal populations. Initially, we investigated the excitatory induction effect of EIN to pyramidal clusters and the external input of EIN. Then, four different targeted treatment approaches (deep brain stimulation (DBS), current balanced biphasic pulse (CBBP), 1:0 coordinated resetting stimulation (1:0 CRS), and 3:2 CRS) were applied to the pyramidal clusters. Moreover, we established two quantitative indices to evaluate the stimulation effects. The results showed that modifying the external input of EIN and the coupling strength projected onto the pyramidal clusters can effectively transition the system from an absence seizure state to other normal states. Additionally, inputs from the left compartment were found to reduce the generation of abnormal discharge regions in the right compartment. Furthermore, considering the treatment effects and current consumption, the 3:2 CRS stimulation strategy appeared to be the most suitable treatment approach for the pyramidal clusters. This work introduces a novel coupled model containing EIN, which contributes new theoretical foundations and insights for the future treatment of absence seizures.
Citation: Quanjun Wu, Zhu Zhang, Ranran Li, Yufan Liu, Yuan Chai. Regulatory role of excitatory interneurons by combining electrical stimulation for absence seizures in the coupled thalamocortical model[J]. Electronic Research Archive, 2024, 32(3): 1533-1550. doi: 10.3934/era.2024070
[1] | Mônica H. M. Nascimento, Milena T. Pelegrino, Joana C. Pieretti, Amedea B. Seabra . How can nitric oxide help osteogenesis?. AIMS Molecular Science, 2020, 7(1): 29-48. doi: 10.3934/molsci.2020003 |
[2] | Jehad Shaikhali, Gunnar Wingsle . Redox-regulated transcription in plants: Emerging concepts. AIMS Molecular Science, 2017, 4(3): 301-338. doi: 10.3934/molsci.2017.3.301 |
[3] | M.Bansbach Heather, H.Guilford William . Actin nitrosylation and its effect on myosin driven motility. AIMS Molecular Science, 2016, 3(3): 426-438. doi: 10.3934/molsci.2016.3.426 |
[4] | Carlos Gutierrez-Merino, Dorinda Marques-da-Silva, Sofia Fortalezas, Alejandro K. Samhan-Arias . The critical role of lipid rafts nanodomains in the cross-talk between calcium and reactive oxygen and nitrogen species in cerebellar granule neurons apoptosis by extracellular potassium deprivation. AIMS Molecular Science, 2016, 3(1): 12-29. doi: 10.3934/molsci.2016.1.12 |
[5] | Michael W Patt, Lisa Conte, Mary Blaha, Balbina J Plotkin . Steroid hormones as interkingdom signaling molecules: Innate immune function and microbial colonization modulation. AIMS Molecular Science, 2018, 5(1): 117-130. doi: 10.3934/molsci.2018.1.117 |
[6] | Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, Adel S. Al-Zubairi, Ahmad Syahida, Lee KaHeng, Putri Narrima, Rozana Othman, Hassan Ahmad Alfaifi, Amal Hamdan Alzahrani . Anti-inflammatory and antioxidant properties of bark and fruit extracts of Faidherbia albida (Delile) A. Chev: A perspective from bio-prospecting assays to scientometric approach. AIMS Molecular Science, 2024, 11(3): 262-276. doi: 10.3934/molsci.2024016 |
[7] | Zhaoping Qin, Patrick Robichaud, Taihao Quan . Oxidative stress and CCN1 protein in human skin connective tissue aging. AIMS Molecular Science, 2016, 3(2): 269-279. doi: 10.3934/molsci.2016.2.269 |
[8] | Sayeeda Ahsanuddin, Minh Lam, Elma D. Baron . Skin aging and oxidative stress. AIMS Molecular Science, 2016, 3(2): 187-195. doi: 10.3934/molsci.2016.2.187 |
[9] | Akshaj Pole, Manjari Dimri, Goberdhan P. Dimri . Oxidative stress, cellular senescence and ageing. AIMS Molecular Science, 2016, 3(3): 300-324. doi: 10.3934/molsci.2016.3.300 |
[10] | Giulia Ambrosi, Pamela Milani . Endoplasmic reticulum, oxidative stress and their complex crosstalk in neurodegeneration: proteostasis, signaling pathways and molecular chaperones. AIMS Molecular Science, 2017, 4(4): 424-444. doi: 10.3934/molsci.2017.4.424 |
The role of excitatory interneurons (EINs) in the cortical has received increasing attention in the discussion of absence seizures. Numerous physiological experiments have confirmed the correlation between EIN and absence seizures. However, the dynamic mechanisms underlying this relationship are not well understood, and there are some challenges in selecting appropriate stimulation strategies for pyramidal clusters. In this study, we incorporated EIN into the previous Taylor model and developed an improved thalamocortical coupled model consisting of ten neuronal populations. Initially, we investigated the excitatory induction effect of EIN to pyramidal clusters and the external input of EIN. Then, four different targeted treatment approaches (deep brain stimulation (DBS), current balanced biphasic pulse (CBBP), 1:0 coordinated resetting stimulation (1:0 CRS), and 3:2 CRS) were applied to the pyramidal clusters. Moreover, we established two quantitative indices to evaluate the stimulation effects. The results showed that modifying the external input of EIN and the coupling strength projected onto the pyramidal clusters can effectively transition the system from an absence seizure state to other normal states. Additionally, inputs from the left compartment were found to reduce the generation of abnormal discharge regions in the right compartment. Furthermore, considering the treatment effects and current consumption, the 3:2 CRS stimulation strategy appeared to be the most suitable treatment approach for the pyramidal clusters. This work introduces a novel coupled model containing EIN, which contributes new theoretical foundations and insights for the future treatment of absence seizures.
Consider the following Euler-Poisson system for the bipolar hydrodynamical model of semi-conductor devices:
{n1t+j1x=0,j1t+(j21n1+p(n1))x=n1E−j1,n2t+j2x=0,j2t+(j22n2+q(n2))x=−n2E−j2,Ex=n1−n2−D(x), | (1) |
in the region Ω=(0,1)×R+. In this paper, n1(x,t), n2(x,t), j1(x,t), j2(x,t) and E(x,t) represent the electron density, the hole density, the electron current density, the hole current density and the electric field, respectively. In this note, we assume that the p and q satisfy the γ-law:p(n1)=n21 and q(n2)=n22 (γ=2), which denote the pressures of the electrons and the holes. The function D(x), called the doping profile, stands for the density of impurities in semiconductor devices.
For system (1), the initial conditions are
ni(x,0)=ni0(x)≥0,ji(x,0)=ji0(x),i=1,2, | (2) |
and the boundary conditions at x=0 and x=1 are
ji(0,t)=ji(1,t)=0,i=1,2,E(0,t)=0. | (3) |
So, we can get the compatibility condition
ji0(0)=ji0(1)=0,i=1,2. | (4) |
Moreover, in this paper, we assume the doping profile D(x) satisfies
D(x)∈C[0,1] and D∗=supxD(x)≥infxD(x)=D∗. | (5) |
Now, the definition of entropy solution to problem (1)−(4) is given. We consider the locally bounded measurable functions n1(x,t), j1(x,t), n2(x,t), j2(x,t), E(x,t), where E(x,t) is continuous in x, a.e. in t.
Definition 1.1. The vector function (n1,n2,j1,j2,E) is a weak solution of problem (1)−(4), if it satisfies the equation (1) in the distributional sense, verifies the restriction (2) and (3). Furthermore, a weak solution of system (1)−(4) is called an entropy solution if it satisfies the entropy inequality
ηet+qex+j21n1+j22n2−j1E+j2E≤0, | (6) |
in the sense of distribution. And the (ηe,qe) are mechanical entropy-entropy flux pair which satisfy
{ηe(n1,n2,j1,j2)=j212n1+n21+j222n2+n22,qe(n1,n2,j1,j2)=j312n21+2n1j1+j322n22+2n2j2. | (7) |
For bipolar hydrodynamic model, the studies on the existence of solutions and the large time behavior as well as relaxation-time limit have been extensively carried out, for example, see [1][2][3][4][5][6] etc. Now, we make it into a semilinear ODE about the potential and the pressures with the exponent γ=2. We can get the existence, uniqueness and some bounded estimates of the steady solution. Then, using a technical energy method and a entropy dissipation estimate, we present a framework for the large time behavior of bounded weak entropy solutions with vacuum. It is shown that the weak solutions converge to the stationary solutions in L2 norm with exponential decay rate.
The organization of this paper is as follows. In Section 2, the existence, uniqueness and some bounded estimates of stationary solutions are given. we present a framework for the large time behavior of bounded weak entropy solutions with vacuum in Section 3.
In this part, we will prove the existence and uniqueness of steady solution to problem (1)−(4). Moreover, we can obtain some important estimates on the steady solution (N1,N2,E).
The steady equation of (1)−(4) is as following
{J1=J2=0,2N1N1x=N1E,2N2N2x=−N2E,Ex=N1−N2−D(x), | (8) |
and the boundary condition
E(0)=0. | (9) |
We only concern the classical solutions in the region where the density
infxN1>0 and infxN2>0. | (10) |
hold.
Now, we introduce a new variation Φ(x), and make Φ′(x): = E(x). To eliminate the additive constants, we set ∫10Φ(x)dx=0. Then (2.1) turns into
{2N1x=Φx,2N2x=−Φx,Φxx=N1−N2−D(x). | (11) |
Obviously, (11)1 and (11)2 indicate
{N1(x)=12Φ(x)+C1,N2(x)=−12Φ(x)+C2,Φxx(x)=12Φ(x)+C1+12Φ(x)−C2−D(x). | (12) |
where C1 and C2 are two unknown positive constants. To calculate these two constants, we suppose*
*Using the conservation of the total charge: integrating (1)1 and (1)3 from 0 to 1
(∫10nidx)t=−∫10jixdx=0, for i=1,2, |
we see this assumption is right.
∫10(ni(x,0)−Ni(x))dx=0 for i=1,2, | (13) |
then
ˉn1:=∫10n1(x,0)dx=∫10N1(x)dx=∫10(Φ(x)2+C1)dx=C1,ˉn2:=∫10n2(x,0)dx=∫10N2(x)dx=∫10(−Φ(x)2+C2)dx=C2. | (14) |
Substituting (14) into (12)3, we have
Φxx=Φ(x)+ˉn1−ˉn2−D(x). | (15) |
Clearly, we can prove the existence and uniqueness of solutions to (15) with the Neumann boundary condition
Φx(0)=Φx(1)=0. | (16) |
Integrate(15) from x=0 to x=1, we get
ˉn1−ˉn2=∫10D(x)dx. | (17) |
Suppose Φ(x) attains its maximum in x0∈[0,1], then we get Φxx(x0)≤0† and
† If x0∈(0,1), then Φx(x0)=0, Φxx(x0)≤0 clearly. If x0=0 or x0=1, the Taylor expansion
Φ(x)=Φ(x0)+Φ′(x0)(x−x0)+Φ″(x0)2(x−x0)2+o(x−x0)2, |
the boundary condition (16) indicates Φ″(x0)≤0.
Φ(x0)+ˉn1−ˉn2−D(x0)≤0. |
So we get
Φ(x0)≤D∗+ˉn2−ˉn1. | (18) |
Similarly, if Φ attains its minimum in x1∈[0,1], we obtain
Φ(x1)≥D∗+ˉn2−ˉn1. | (19) |
Moreover, from (12),(14),(15),(18), and (19), we have
D∗+ˉn2+ˉn12≤N1(x)≤D∗+ˉn2+ˉn12,−D∗+ˉn2+ˉn12≤N2(x)≤−D∗+ˉn2+ˉn12, | (20) |
D∗≤(N1−N2)(x)≤D∗ for any x∈[0,1]. | (21) |
Above that, the theorem of existence and uniqueness of steady equation is given.
Theorem 2.1. Assume that (5) holds, then problem (8), (9) has an unique solution (N1,N2,E), such that for any x∈[0,1]
n∗≤N1(x)≤n∗, n∗≤N2(x)≤n∗, | (22) |
and
D∗≤(N1−N2)(x)≤D∗, | (23) |
satisfy, where
n∗:=max{D∗+ˉn2+ˉn12,−D∗+ˉn2+ˉn12},n∗:=min{D∗+ˉn2+ˉn12,−D∗+ˉn2+ˉn12}, | (24) |
ˉn1, ˉn2 are defined in (14).
Now, our aim is to prove the weak-entropy solution of (1)−(4) convergences to corresponding stationary solution in L2 norm with exponential decay rate. For this purpose, we introduce the relative entropy-entropy flux pair:
η∗(x,t)=2∑i=1(j2i2ni+n2i−N2i−2Ni(ni−Ni))(x,t)=(ηe−2∑i=1Qi)(x,t)≥0, | (25) |
q∗(x,t)=2∑i=1(j3i2n2i+2niji−2Niji)(x,t)=(qe−2∑i=1Pi)(x,t), | (26) |
where
Qi=N2i+2Ni(ni−Ni),Pi=2Niji, |
ηe and qe are the entropy-entropy flux pair defined in (1.7).
The following theorem is our main result in section 3.
Theorem 3.1(Large time behavior) Suppose (n1,n2,j1,j2,E)(x,t) be any weak entropy solution of problem (1.1)−(1.4) satisfying
2(2D∗−ˉn1−ˉn2)<(n1−n2)(x,t)<2(2D∗+ˉn1+ˉn2), | (27) |
for a.e. x∈[0,1] and t>0. (N1,N2,E)(x) is its stationary solution obtained in Theorem 2.1. If
∫10η∗(x,0)dx<∞, ∫10(ni(s,0)−Ni(s))ds=0, | (28) |
then for any t>0, we have
∫10[j21+j22+(E−E)2+(n1−N1)2+(n2−N2)2](x,t)dx≤C0e−˜C0t∫10η∗(x,0)dx. | (29) |
holds for some positive constant C0 and ˜C0 .
Proof. We set
yi(x,t)=−∫x0(ni(s,t)−Ni(s))ds, i=1,2, x∈[0,1], t>0. | (30) |
Clearly, yi(i=1,2) is absolutely continuous in x for a.e. t>0. And
yix=−(ni−Ni),yit=ji,y2−y1=E−E,yi(0,t)=yi(1,t)=0, | (31) |
following (1.1), (2.1), and (2.1). From (1.1)2 and (2.1)2, we get y1 satisfies the equation
y1tt+(y21tn1)x−y1xx+y1t=n1E−N1E. | (32) |
Multiplying y1 with (32) and integrating over (0,1)‡, we have
‡For weak solutions, (1) satisfies in the sense of distribution. We choose test function φn(x,t)∈C∞0((0,1)×[0,T)) and let φn(x,t)→yi(x,t) as n→+∞ for i=1,2.
ddt∫10(y1y1t+12y21) dx−∫10(y21tn1)y1x dx−∫10(n21−N21)y1xdx−∫10y21t dx=∫10(N1(y2−y1)y1+Ex2y21)dx. | (33) |
In above calculation, we have used the integration by part. Similarly, from (1.1)4 and (2.1)3, we get
ddt∫10(y2y2t+12y22) dx−∫10(y22tn2)y2x dx−∫10(n22−N22)y2x dx−∫10y22t dx=−∫10(N2(y2−y1)y2+Ex2y22) dx. | (34) |
Add (33) and (34), we have
ddt∫10(y1y1t+12y21+y2y2t+12y22) dx−∫10(n21−N21)y1xdx−∫10(n22−N22)y2x dx=∫10((y21tn1)y1x +(y22tn2)y2x) dx+∫10(y21t+y22t) dx+∫10(N1(y2−y1)y1+Ex2y21−N2(y2−y1)y2−Ex2y22) dx. | (35) |
Since
∫10(N1(y2−y1)y1+Ex2y21−N2(y2−y1)y2−Ex2y22) dx=∫10n1−N1−n2+N2−D(x)2y21dx+∫10n2−N2−n1+N1+D(x)2y22dx−∫10N1+N22(y1−y2)2dx, | (36) |
then, from (31)1 and (36) we get
ddt∫10(y1y1t+12y21+y2y2t+12y22) dx+∫10(N1+n1)y21x+∫10(N2+n2)y22xdx+∫10N1+N22(y1−y2)2dx=∫10((y21tn1)y1x+(y22tn2)y2x) dx+∫10(y21t+y22t) dx+∫10(n1−N1−n2+N2−D(x)2y21+n2−N2−n1+N1+D(x)2y22)dx. | (37) |
Moreover, since
|yi(x)|=|∫x0yis(s)ds|≤x12(∫x0y2isds)12≤x12(∫10y2isds)12,x∈[0,1], | (38) |
we can obtain
‖yi‖2L2=∫10|yi|2dx≤12‖yix‖2L2, | (39) |
verifies for i=1,2. If the weak solutions n1(x,t) and n2(x,t) satisfy (27) then
infx{N1+n1}>supx{n1−N1−n2+N2−D(x)4}, | (40) |
and
infx{N2+n2}>supx{n2−N2−n1+N1+D(x)4}, | (41) |
hold, where we have used the assumption (5) and the estimate (23).
Following (39), (40) and (41), we have
∫10n1−N1−n2+N2−D(x)2y21dx<∫10(N1+n1)y21xdx, | (42) |
and
∫10n2−N2−n1+N1+D(x)2y22dx<∫10(N2+n2)y22xdx. | (43) |
Thus (36), (42), and (43) indicate there is a positive constant β>0, such that
ddt∫10(y1y1t+12y21+y2y2t+12y22) dx+β∫10(y21x+y22x)dx+∫10N1+N22(y1−y2)2dx≤∫10((y21tn1)y1x+(y22tn2)y2x) dx+∫10(y21t+y22t) dx=∫10(N1y21tn1+N2y22tn2) dx. | (44) |
In view of the entropy inequality (6), and the definition of η∗ and q∗ in (25) and (26), the following inequality holds in the sense of distribution.
ηet+qex+j21n1+j22n2−j1E+j2E=η∗t+2∑i=1Qit+q∗x+2∑i=1Pix+j21n1+j22n2−j1E+j2E=η∗t+q∗x+j21n1+j22n2−j1E+j2E+j1E−j2E≤0. | (45) |
Since
−j1E+j2E+j1E−j2E=(E−E)(j2−j1)=(y2−y1)(y2t−y1t), | (46) |
then (44) turns into
η∗t+q∗x+y21tn1+y22tn2+(y2−y1)(y2t−y1t)≤0. | (47) |
We use the theory of divergence-measure fields, then
ddt∫10(η∗+12(y2−y1)2)dx+∫10(y21tn1+y22tn2) dx ≤0, | (48) |
where we use the fact
∫10q∗x dx =0. | (49) |
Let λ>2+2n∗>0. Then, we multiply (48) by λ and add the result to (44) to get
ddt∫10(λη∗+λ2(y2−y1)2+y1y1t+12y21+y2y2t+12y22)dx+β∫10(y21x+y22x)dx+∫10N1+N22(y1−y2)2dx+∫10((λ−N1)y21tn1+(λ−N2)y22tn2)dx≤0. | (50) |
Using the estimate (22) in Theorem 2.1. and the Poincˊare inequality (39), we have
ddt∫10(λη∗+λ2(y2−y1)2+y1y1t+12y21+y2y2t+12y22)dx+β2∫10(y21x+y22x)dx+β2∫10(y21+y22)dx+n∗∫10(y1−y2)2dx+∫10(y21tn1+y22tn2)dx≤0. | (51) |
Now, we consider η∗ in (25). Clearly
n2i−N2i−2Ni(ni−Ni), | (52) |
is the quadratic remainder of the Taylor expansion of the function n2i around Ni>n∗>0 for i=1,2. And then, there exist two positive constants C1 and C2 such that
C1y2ix≤n2i−N2i−2Ni(ni−Ni)≤C2y2ix. | (53) |
Making C3=min{C1,12} and C4=max{C2,12}, then we get
C3(y21tn1+y22tn2+y21x+y22x)≤η∗≤C4(y21tn1+y22tn2+y21x+y22x). | (54) |
Let
F(x,t)=λη∗+λ2(y2−y1)2+y1y1t+12y21+y2y2t+12y22, |
then there exist positive constants C5, C6, and C7, depending on λ,n∗,β, such that
∫10F(x,t)dx=∫10[λη∗+λ2(y2−y1)2+y1y1t+12y21+y2y2t+12y22]dx≤C5∫10[(y21tn1+y22tn2)+n∗(y2−y1)2+β2(y21x+y22x) +β2(y21+y22)]dx≤C6∫10η∗dx, | (55) |
and
0<C7∫10[(y21tn1+y22tn2)+n∗(y2−y1)2+β2(y21x+y22x) +β2(y21+y22)]dx≤∫10[λη∗+λ2(y2−y1)2+y1y1t+12y21+y2y2t+12y22]dx=∫10F(x,t)dx. | (56) |
Then
ddt∫10F(x,t) dx+1C5∫10F(x,t)dx≤0, | (57) |
and
∫10[(y21tn1+y22tn2)+n∗(y2−y1)2+β2(y21x+y22x) +β2(y21+y22)]dx≤1C7∫10F(x,t)dx≤1C7e−tC5∫10F(x,0)dx≤C8e−tC5∫10η∗(x,0)dx. | (58) |
are given, following the Growall inequality and the estimates (55) and (56). Up to now, we finish the proof of Theorem 3.1.
In the process of the selected topic and write a paper, I get the guidance from my tutor: Huimin Yu. In the teaching process, my tutor helps me develop thinking carefully. The spirit of meticulous and the rigorous attitude of my tutor gives me a lot of help. Gratitude to my tutor is unable to express in words. And this paper supported in part by Shandong Provincial Natural Science Foundation (Grant No. ZR2015AM001).
The author declare no conflicts of interest in this paper.
[1] |
Y. Yu, F. Han, Q. Wang, A hippocampal-entorhinal cortex neuronal network for dynamical mechanisms of epileptic seizure, IEEE Trans. Neural Syst. Rehabil. Eng., 31 (2023), 1986–1996. https://doi.org/10.1109/TNSRE.2023.3265581 doi: 10.1109/TNSRE.2023.3265581
![]() |
[2] |
E. Akyuz, A. K. Polat, E. Eroglu, I. Kullu, E. Angelopoulou, Y. N. Paudel, Revisiting the role of neurotransmitters in epilepsy: An updated review, Life Sci., 265 (2021), 118826. https://doi.org/10.1016/j.seizure.2013.01.008 doi: 10.1016/j.seizure.2013.01.008
![]() |
[3] | R. D. Thijs, R. Surges, T. J. O'Brien, J. W. Sander, Epilepsy in adults, Lancet, 393 (2019), 689–701. https://doi.org/10.1016/S0140-6736(18)32596-0 |
[4] |
S. Gregorčič, J. Hrovat, N. Bizjak, P. Z. Rener, T. Hostnik, B. Stres, et al., Difficult to treat absence seizures in children: A single-center retrospective study, Front. Neurol., 13 (2022), 958369. https://doi.org/10.3389/fneur.2022.958369 doi: 10.3389/fneur.2022.958369
![]() |
[5] |
Z. W. Wong, T. Engel, More than a drug target: Purinergic signalling as a source for diagnostic tools in epilepsy, Neuropharmacology, 222 (2023), 109303. https://doi.org/10.1016/j.neuropharm.2022.109303 doi: 10.1016/j.neuropharm.2022.109303
![]() |
[6] |
R. S. Fisher, C. Acevedo, A. Arzimanoglou, A. Bogacz, J. H. Cross, C. E. Elger, et al., ILAE official report: a practical clinical definition of epilepsy, Epilepsia, 55 (2014), 475–482. https://doi.org/10.1111/epi.12550 doi: 10.1111/epi.12550
![]() |
[7] |
J. Xue, P. Gong, H. Yang, X. Liu, Y. Jiang, Y. Zhang, et al., Genetic (idiopathic) epilepsy with photosensitive seizures includes features of both focal and generalized seizures, Sci. Rep., 8 (2018), 6254. https://doi.org/10.1038/s41598-018-24644-0 doi: 10.1038/s41598-018-24644-0
![]() |
[8] |
Z. Liu, F. Han, Q. Wang, A review of computational models for gamma oscillation dynamics: from spiking neurons to neural masses, Nonlinear Dyn., 108 (2022), 1849–1866. https://doi.org/10.1007/s11071-022-07298-6 doi: 10.1007/s11071-022-07298-6
![]() |
[9] |
D. Pinault, T. J. O'brien, Cellular and network mechanisms of genetically-determined absence seizures, Thalamus Relat. Syst., 3 (2005), 181–203. https://doi.org/10.1017/S1472928807000209 doi: 10.1017/S1472928807000209
![]() |
[10] |
S. Bhattacharya, M. B. L. Cauchois, P. A. Iglesias, Z. S. Chen, The impact of a closed-loop thalamocortical model on the spatiotemporal dynamics of cortical and thalamic traveling waves, Sci. Rep., 11 (2021), 14359. https://doi.org/10.1038/s41598-021-93618-6 doi: 10.1038/s41598-021-93618-6
![]() |
[11] |
P. N. Taylor, Y. Wang, M. Goodfellow, J. Dauwels, F. Moeller, U. Stephani, et al., A computational study of stimulus driven epileptic seizure abatement, PLoS One, 9 (2014), 1–26. https://doi.org/10.1371/journal.pone.0114316 doi: 10.1371/journal.pone.0114316
![]() |
[12] |
S. I. Amari, Characteristics of randomly connected threshold-element networks and network systems, Proc. IEEE, 59 (1971), 35–47. https://doi.org/10.1109/PROC.1971.8087 doi: 10.1109/PROC.1971.8087
![]() |
[13] |
H. R. Wilson, J. D. Cowan, Excitatory and inhibitory interactions in localized populations of model neurons, Biophys. J., 12 (1972), 1–24. https://doi.org/10.1016/S0006-3495(72)86068-5 doi: 10.1016/S0006-3495(72)86068-5
![]() |
[14] |
M. Goodfellow, K. Schindler, G. Baier, Intermittent spike-wave dynamics in a heterogeneous, spatially extended neural mass model, NeuroImage, 55 (2011), 920–932. https://dx.doi.org/10.1016/j.neuroimage.2010.12.074 doi: 10.1016/j.neuroimage.2010.12.074
![]() |
[15] |
P. N. Taylor, J. Thomas, N. Sinha, J. Dauwels, M. Kaiser, T. Thesen, et al., Optimal control based seizure abatement using patient derived connectivity, Front. Neurosci., 9 (2015), 202. https://doi.org/10.3389/fnins.2015.00202 doi: 10.3389/fnins.2015.00202
![]() |
[16] |
S. Liu, Q. Wang, Transition dynamics of generalized multiple epileptic seizures associated with thalamic reticular nucleus excitability: A computational study, Commun. Nonlinear Sci. Numer. Simul., 52 (2017), 203–213. https://doi.org/10.1016/j.cnsns.2017.04.035 doi: 10.1016/j.cnsns.2017.04.035
![]() |
[17] |
Y. Cao, X. He, Y. Hao, Q. Wang, Transition dynamics of epileptic seizures in the coupled thalamocortical network model, Int. J. Bifurcation Chaos, 28 (2018), 1850104. https://doi.org/10.1142/S0218127418501043 doi: 10.1142/S0218127418501043
![]() |
[18] |
L. Yan, H. Zhang, Z. Sun, Z. Shen, Control analysis of electrical stimulation for epilepsy waveforms in a thalamocortical network, J. Theor. Biol., 504 (2020), 110391. https://doi.org/10.1016/j.jtbi.2020.110391 doi: 10.1016/j.jtbi.2020.110391
![]() |
[19] |
Z. Wang, L. Duan, The combined effects of the thalamic feed-forward inhibition and feed-back inhibition in controlling absence seizures, Nonlinear Dyn., 108 (2022), 191–205. https://doi.org/10.1007/s11071-021-07178-5 doi: 10.1007/s11071-021-07178-5
![]() |
[20] |
A. Somarowthu, K. M. Goff, E. M. Goldberg, Two-photon calcium imaging of seizures in awake, head-fixed mice, Cell Calcium, 96 (2021), 102380. https://doi.org/10.1016/j.ceca.2021.102380 doi: 10.1016/j.ceca.2021.102380
![]() |
[21] |
M. Steriade, Interneuronal epileptic discharges related to spike-and-wave cortical seizures in behaving monkeys, Electroencephalogr. Clin. Neurophysiol., 37 (1974), 247–263. https://doi.org/10.1016/0013-4694(74)90028-5 doi: 10.1016/0013-4694(74)90028-5
![]() |
[22] |
S. Tabatabaee, F. Bahrami, M. Janahmadi, The critical modulatory role of spiny stellate cells in seizure onset based on dynamic analysis of a neural mass model, Front. Neurosci., 15 (2021), 743720. https://doi.org/10.3389/fnins.2021.743720 doi: 10.3389/fnins.2021.743720
![]() |
[23] | L. Yan, H. Zhang, Z. Sun, Z. Cao, Z. Shen, Y. Zhao, Mechanism analysis for excitatory interneurons dominating poly-spike wave and optimization of electrical stimulation, Chaos Interdiscip. J. Nonlinear Sci., 32 (2022). https://doi.org/10.1063/5.0076439 |
[24] |
L. Yan, H. Zhang, Z. Sun, S. Liu, Y. Liu, P. Xiao, Optimization of stimulation waveforms for regulating spike-wave discharges in a thalamocortical model, Chaos, Solitons Fractals, 158 (2022), 112025. https://doi.org/10.1016/j.chaos.2022.112025 doi: 10.1016/j.chaos.2022.112025
![]() |
[25] |
Y. Yu, X. Wang, Q. Wang, Q. Y. Wang, A review of computational modeling and deep brain stimulation: applications to Parkinson's disease, Appl. Math. Mech., 41 (2020), 1747–1768. https://doi.org/10.1007/s10483-020-2689-9 doi: 10.1007/s10483-020-2689-9
![]() |
[26] |
O. V. Popovych, P. A. Tass, Multisite delayed feedback for electrical brain stimulation, Front. Physiol., 9 (2018), 46. https://doi.org/10.3389/fphys.2018.00046 doi: 10.3389/fphys.2018.00046
![]() |
[27] |
Z. Wang, Q. Wang, Stimulation strategies for absence seizures: targeted therapy of the focus in coupled thalamocortical model, Nonlinear Dyn., 96 (2019), 1649–1633. https://doi.org/10.1007/s11071-019-04876-z doi: 10.1007/s11071-019-04876-z
![]() |
[28] |
Y. Yu, Y. Fan, F. Han, G. Luan, Q. Wang, Transcranial direct current stimulation inhibits epileptic activity propagation in a large-scale brain network model, Sci. China Technol. Sci., 66 (2023), 3628–3638. https://doi.org/10.1007/s11431-022-2341-x doi: 10.1007/s11431-022-2341-x
![]() |
[29] |
S. Hou, D. Fan, Q. Wang, Regulating absence seizures by tri-phase delay stimulation applied to globus pallidus internal, Appl. Math. Mech., 43 (2022), 1399–1414. https://doi.org/10.1007/s10483-022-2896-7 doi: 10.1007/s10483-022-2896-7
![]() |
[30] |
P. A. Tass, L. Qin, C. Hauptmann, S. Dovero, E. Bezard, T. Boraud, et al., Coordinated reset has sustained aftereffects in Parkinsonian monkeys, Ann. Neurol., 72 (2012), 816–820. https://doi.org/10.1002/ana.23663 doi: 10.1002/ana.23663
![]() |
[31] |
D. Fan, Q. Wang, Closed-loop control of absence seizures inspired by feedback modulation of basal ganglia to the corticothalamic circuit, IEEE Trans. Neural Syst. Rehabil. Eng., 28 (2020), 581–590. https://doi.org/10.1109/TNSRE.2020.2969426 doi: 10.1109/TNSRE.2020.2969426
![]() |
[32] |
N. Sinha, J. Dauwels, M. Kaiser, S. Cash, W. M. Brandon, Y. Wang, et al., Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling, Brain, 140 (2017), 319–332. https://doi.org/10.1093/brain/aww299 doi: 10.1093/brain/aww299
![]() |
[33] |
D. Fan, Q. Wang, J. Su, H. Xi, Stimulus-induced transitions between spike-wave discharges and spindles with the modulation of thalamic reticular nucleus, J. Comput. Neurosci., 43 (2017), 203–225. https://doi.org/10.1007/s10827-017-0658-4 doi: 10.1007/s10827-017-0658-4
![]() |
[34] |
L. Yin, F. Han, Y. Yu, Q. Wang, A computational network dynamical modeling for abnormal oscillation and deep brain stimulation control of obsessive–compulsive disorder, Cognit. Neurodyn., 17 (2023), 1167–1184. https://doi.org/10.1007/s11571-022-09858-3 doi: 10.1007/s11571-022-09858-3
![]() |
[35] |
X. Wang, Y. Yu, F. H, Q. Wang, Beta-band bursting activity in computational model of heterogeneous external globus pallidus circuits, Commun. Nonlinear Sci. Numer. Simul., 110 (2022), 106388. https://doi.org/10.1016/j.cnsns.2022.106388 { doi: 10.1016/j.cnsns.2022.106388
![]() |
[36] |
Y. Yu, Y. Fan, S. Hou, Q. Wang, Optogenetic stimulation of primary motor cortex regulates beta oscillations in the basal ganglia: A Computational study, Commun. Nonlinear Sci. Numer. Simul., 117 (2023), 106918. https://doi.org/10.1016/j.cnsns.2022.106918 doi: 10.1016/j.cnsns.2022.106918
![]() |
[37] |
K. B. Baker, E. B. Plow, S. Nagel, A. B. Rosenfeldt, R. Gopalakrishnan, C. Clark, et al., Cerebellar deep brain stimulation for chronic post-stroke motor rehabilitation: a phase I trial, Nat. Med., 29 (2023), 2366–2374. https://doi.org/10.1038/s41591-023-02507-0 doi: 10.1038/s41591-023-02507-0
![]() |
[38] |
T. Loddenkemper, A. Pan, S. Neme, K. B. Baker, A. R. Rezai, D. S. Dinner, et al., Deep brain stimulation in epilepsy, J. Clin. Neurophysiol., 18 (2001), 514–532. https://doi.org/10.1097/00004691-200111000-00002 doi: 10.1097/00004691-200111000-00002
![]() |
[39] |
D. Fan, Z. Wang, Q. Wang, Optimal control of directional deep brain stimulation in the parkinsonian neuronal network, Commun. Nonlinear Sci. Numer. Simul., 36 (2016), 219–237. https://doi.org/10.1016/j.cnsns.2015.12.005 doi: 10.1016/j.cnsns.2015.12.005
![]() |
[40] |
J. J. Lippman-Bell, C. Zhou, H. Sun, J. S. Feske, F. E. Jensen, Early-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity, Mol. Cell. Neurosci., 76 (2016), 11–20. https://doi.org/10.1016/j.mcn.2016.08.002 doi: 10.1016/j.mcn.2016.08.002
![]() |
[41] |
C. H. Tran, M. Vaiana, J. Nakuci, A. Somarowthu, K. M. Goff, N. Goldstein, et al., Interneuron desynchronization precedes seizures in a mouse model of Dravet syndrome, J. Neurosci., 40 (2020), 2764–2755. https://doi.org/10.1523/JNEUROSCI.2370-19.2020 doi: 10.1523/JNEUROSCI.2370-19.2020
![]() |
[42] |
A. Satlin, L. Kramer, A. Laurenza, Development of perampanel in epilepsy, Acta Neurol. Scand., 127 (2013), 3–8. https://doi.org/10.1111/ane.12098 doi: 10.1111/ane.12098
![]() |
[43] |
M. V. Sysoeva, A. Lüttjohann, G. V. Luijtelaar, I. V. Sysoev, Dynamics of directional coupling underlying spike-wave discharges, Neuroscience, 314 (2016), 75–89. https://doi.org/10.1016/j.neuroscience.2015.11.044 doi: 10.1016/j.neuroscience.2015.11.044
![]() |
[44] |
Y. Yu, F. Han, Q. Wang, Q. Y. Wang, Model-based optogenetic stimulation to regulate beta oscillations in Parkinsonian neural networks, Cognit. Neurodyn., 16 (2022), 667–681. https://doi.org/10.1007/s11571-021-09729-3 doi: 10.1007/s11571-021-09729-3
![]() |
[45] |
M. Lv, J. Ma, Multiple modes of electrical activities in a new neuron model under electromagnetic radiation, Neurocomputing, 205 (2016), 375–381. https://doi.org/10.1016/j.neucom.2016.05.004 doi: 10.1016/j.neucom.2016.05.004
![]() |
1. | Savita Duhan, 2021, 9780128193822, 195, 10.1016/B978-0-12-819382-2.00011-9 | |
2. | Gonzalo R. Tortella, Olga Rubilar, María Cristina Diez, Jorge Padrão, Andrea Zille, Joana C. Pieretti, Amedea B. Seabra, Advanced Material Against Human (Including Covid‐19) and Plant Viruses: Nanoparticles As a Feasible Strategy, 2021, 5, 2056-6646, 2000049, 10.1002/gch2.202000049 | |
3. | Y. Q. An, L. Sun, X. J. Wang, R. Sun, Z. Y. Cheng, Z. K. Zhu, G. G. Yan, Y. X. Li, J. G. Bai, Vanillic Acid Mitigates Dehydration Stress Responses in Blueberry Plants, 2019, 66, 1021-4437, 806, 10.1134/S1021443719050029 | |
4. | Nkulu Kabange Rolly, Sang-Uk Lee, Qari Muhammad Imran, Adil Hussain, Bong-Gyu Mun, Kyung-Min Kim, Byung-Wook Yun, Nitrosative stress-mediated inhibition of OsDHODH1 gene expression suggests roots growth reduction in rice (Oryza sativa L.), 2019, 9, 2190-572X, 10.1007/s13205-019-1800-y | |
5. | Patrícia Juliana Lopes-Oliveira, Diego Genuário Gomes, Milena Trevisan Pelegrino, Edmilson Bianchini, José Antonio Pimenta, Renata Stolf-Moreira, Amedea Barozzi Seabra, Halley Caixeta Oliveira, Effects of nitric oxide-releasing nanoparticles on neotropical tree seedlings submitted to acclimation under full sun in the nursery, 2019, 9, 2045-2322, 10.1038/s41598-019-54030-3 | |
6. | Natalia Napieraj, Małgorzata Reda, Małgorzata Janicka, The role of NO in plant response to salt stress: interactions with polyamines, 2020, 47, 1445-4408, 865, 10.1071/FP19047 | |
7. | Fareen Sami, Husna Siddiqui, Shamsul Hayat, Nitric Oxide-Mediated Enhancement in Photosynthetic Efficiency, Ion Uptake and Carbohydrate Metabolism that Boosts Overall Photosynthetic Machinery in Mustard Plants, 2020, 0721-7595, 10.1007/s00344-020-10166-5 | |
8. | Milena T Pelegrino, Joana C Pieretti, Camila Neves Lange, Marcio Yukihiro Kohatsu, Bruna Moreira Freire, Bruno Lemos Batista, Paola Fincheira, Gonzalo R Tortella, Olga Rubilar, Amedea B Seabra, Foliar spray application of CuO nanoparticles ( NPs ) and S ‐nitrosoglutathione enhances productivity, physiological and biochemical parameters of lettuce plants , 2021, 0268-2575, 10.1002/jctb.6677 | |
9. | M. Pontin, G. Murcia, R. Bottini, A. Fontana, L. Bolcato, P. Piccoli, Nitric oxide and abscisic acid regulate osmoprotective and antioxidative mechanisms related to water stress tolerance of grapevines, 2021, 1322-7130, 10.1111/ajgw.12485 | |
10. | Neidiquele M. Silveira, Rafael V. Ribeiro, Paula J. C. Prataviera, Maria D. Pissolato, Joana C. Pieretti, Amedea B. Seabra, Eduardo C. Machado, Germination and initial growth of common bean plants under water deficit as affected by seed treatment with S-nitrosoglutathione and calcium chloride, 2020, 32, 2197-0025, 49, 10.1007/s40626-020-00166-x | |
11. | Rizwana Begum Syed Nabi, Rupesh Tayade, Adil Hussain, Krishnanand P. Kulkarni, Qari Muhammad Imran, Bong-Gyu Mun, Byung-Wook Yun, Nitric oxide regulates plant responses to drought, salinity, and heavy metal stress, 2019, 161, 00988472, 120, 10.1016/j.envexpbot.2019.02.003 | |
12. | Milena Trevisan Pelegrino, Marcio Yukihiro Kohatsu, Amedea Barozzi Seabra, Lucilena Rebelo Monteiro, Diego Genuário Gomes, Halley Caixeta Oliveira, Wallace Rosado Rolim, Tatiane Araújo de Jesus, Bruno Lemos Batista, Camila Neves Lange, Effects of copper oxide nanoparticles on growth of lettuce (Lactuca sativa L.) seedlings and possible implications of nitric oxide in their antioxidative defense, 2020, 192, 0167-6369, 10.1007/s10661-020-8188-3 | |
13. | Anderson E. S. Pereira, Bruno T. Sousa, María J. Iglesias, Vera A. Alvarez, Claudia A. Casalongué, Halley C. Oliveira, Leonardo F. Fraceto, 2019, Chapter 4, 978-3-030-19415-4, 45, 10.1007/978-3-030-19416-1_4 | |
14. | Yu. V. Karpets, Yu. E. Kolupaev, Functional interaction of nitric oxide with reactive oxygen species and calcium ions at development of plants adaptive responses, 2017, 2017, 19924917, 6, 10.35550/vbio2017.02.006 | |
15. | Angeles Aroca, Cecilia Gotor, Luis C. Romero, Hydrogen Sulfide Signaling in Plants: Emerging Roles of Protein Persulfidation, 2018, 9, 1664-462X, 10.3389/fpls.2018.01369 | |
16. | Angeles Aroca, Cecilia Gotor, Diane C. Bassham, Luis C. Romero, Hydrogen Sulfide: From a Toxic Molecule to a Key Molecule of Cell Life, 2020, 9, 2076-3921, 621, 10.3390/antiox9070621 | |
17. | Alina Wiszniewska, Priming Strategies for Benefiting Plant Performance under Toxic Trace Metal Exposure, 2021, 10, 2223-7747, 623, 10.3390/plants10040623 | |
18. | Vinod Goyal, Dharmendra Jhanghel, Shweta Mehrotra, Emerging warriors against salinity in plants: Nitric oxide and hydrogen sulphide, 2021, 171, 0031-9317, 896, 10.1111/ppl.13380 | |
19. | Sagar Bag, Anupam Mondal, Avishek Banik, 2022, 9781119800156, 95, 10.1002/9781119800156.ch6 | |
20. | A. Tyagi, S. Sharma, S. Ali, K. Gaikwad, M. H. Siddiqui, Crosstalk between H 2 S and NO: an emerging signalling pathway during waterlogging stress in legume crops , 2022, 24, 1435-8603, 576, 10.1111/plb.13319 | |
21. | Marcio Yukihiro Kohatsu, Camila Neves Lange, Milena Trevisan Pelegrino, Joana Claudio Pieretti, Gonzalo Tortella, Olga Rubilar, Bruno Lemos Batista, Amedea Barozzi Seabra, Tatiane Araujo de Jesus, Foliar spraying of biogenic CuO nanoparticles protects the defence system and photosynthetic pigments of lettuce (Lactuca sativa), 2021, 324, 09596526, 129264, 10.1016/j.jclepro.2021.129264 | |
22. | Young Hee Lee, Yun Jeong Kim, Hyong Woo Choi, Yun-Hee Kim, Jeum Kyu Hong, Sodium nitroprusside pretreatment alters responses of Chinese cabbage seedlings to subsequent challenging stresses, 2022, 17, 1742-9145, 206, 10.1080/17429145.2021.2024286 | |
23. | Mobina Ulfat, Habib‐ur‐Rehman Athar, Zafar Ullah Zafar, Muhammad Ashraf, 2022, 9781119800156, 59, 10.1002/9781119800156.ch4 | |
24. | Beáta Piršelová, Ľudmila Galuščáková, Libuša Lengyelová, Veronika Kubová, Vilma Jandová, Jitka Hegrová, Assessment of the Hormetic Effect of Arsenic on Growth and Physiology of Two Cultivars of Maize (Zea mays L.), 2022, 11, 2223-7747, 3433, 10.3390/plants11243433 | |
25. | Nazir Ahmed, Mingyuan Zhu, Qiuxia Li, Xilei Wang, Jiachi Wan, Yushi Zhang, Glycine Betaine-Mediated Root Priming Improves Water Stress Tolerance in Wheat (Triticum aestivum L.), 2021, 11, 2077-0472, 1127, 10.3390/agriculture11111127 | |
26. | Amedea Barozzi Seabra, Milena Trevisan Pelegrino, Patrícia Juliana Lopes-Oliveira, Diego Genuário Gomes, Halley Caixeta Oliveira, 2022, 9780128187975, 3, 10.1016/B978-0-12-818797-5.00012-1 | |
27. | I. Zhigacheva, N. Krikunova, I. Generozova, P. Butsanets, S. Vasilyeva, M. Rasulov, ETRANITROSYL IRON COMPLEX WITH THIOSULFATE LIGANDS PREVENTS MITOCHONDRIAL DYSFUNCTION UNDER STRESS, 2022, 7, 2499-9962, 17, 10.29039/rusjbpc.2022.0477 | |
28. | Aehsan Ul Haq, Mohammad Lateef Lone, Sumira Farooq, Shazia Parveen, Foziya Altaf, Inayatullah Tahir, Daniel Ingo Hefft, Ajaz Ahmad, Parvaiz Ahmad, Suleyman Allakhverdiev, Nitric oxide effectively orchestrates postharvest flower senescence: a case study of, 2021, 50, 1445-4408, 97, 10.1071/FP21241 | |
29. | Huan Yang, Haiying Yu, Yao Wu, Huagang Huang, Xizhou Zhang, Daihua Ye, Yongdong Wang, Zicheng Zheng, Tingxuan Li, Nitric oxide amplifies cadmium binding in root cell wall of a high cadmium-accumulating rice (Oryza sativa L.) line by promoting hemicellulose synthesis and pectin demethylesterification, 2022, 234, 01476513, 113404, 10.1016/j.ecoenv.2022.113404 | |
30. | Milana Trifunović-Momčilov, Nikola Stamenković, Marija Đurić, Snežana Milošević, Marija Marković, Zlatko Giba, Angelina Subotić, Role of Sodium Nitroprusside on Potential Mitigation of Salt Stress in Centaury (Centaurium erythraea Rafn) Shoots Grown In Vitro, 2023, 13, 2075-1729, 154, 10.3390/life13010154 | |
31. | Iraj Azizi, Behrooz Esmaielpour, Hamideh Fatemi, Exogenous nitric oxide on morphological, biochemical and antioxidant enzyme activity on savory (Satureja Hortensis L.) plants under cadmium stress, 2021, 20, 1658077X, 417, 10.1016/j.jssas.2021.05.003 | |
32. | Amedea B. Seabra, Neidiquele M. Silveira, Rafael V. Ribeiro, Joana C. Pieretti, Juan B. Barroso, Francisco J. Corpas, José M. Palma, John T. Hancock, Marek Petřivalský, Kapuganti J. Gupta, David Wendehenne, Gary J. Loake, Jorg Durner, Christian Lindermayr, Árpád Molnár, Zsuzsanna Kolbert, Halley C. Oliveira, Nitric oxide‐releasing nanomaterials: from basic research to potential biotechnological applications in agriculture, 2022, 234, 0028-646X, 1119, 10.1111/nph.18073 | |
33. | Abolghassem Emamverdian, Yulong Ding, James Barker, Guohua Liu, Yang Li, Farzad Mokhberdoran, Sodium Nitroprusside Improves Bamboo Resistance under Mn and Cr Toxicity with Stimulation of Antioxidants Activity, Relative Water Content, and Metal Translocation and Accumulation, 2023, 24, 1422-0067, 1942, 10.3390/ijms24031942 | |
34. | Amedea B. Seabra, Gonzalo R. Tortella, 2023, 9780323988001, 167, 10.1016/B978-0-323-98800-1.00005-8 | |
35. | Simerpreet Kaur Sehgal, Amandeep Kaur, 2023, 9780323912099, 261, 10.1016/B978-0-323-91209-9.00001-4 | |
36. | Jaspreet Kour, Kanika Khanna, Arun Dev Singh, Shalini Dhiman, Kamini Devi, Neerja Sharma, Isha Madaan, Nitika Kapoor, Geetika Sirhindi, Renu Bhardwaj, 2023, 9780323912099, 91, 10.1016/B978-0-323-91209-9.00011-7 | |
37. | Zhi jian Chen, Jing Huang, Su Li, Ji Feng Shao, Ren Fang Shen, Xiao Fang Zhu, Salylic acid minimize cadmium accumulation in rice through regulating the fixation capacity of the cell wall to cadmium, 2023, 336, 01689452, 111839, 10.1016/j.plantsci.2023.111839 | |
38. | Arun Dev Singh, Kanika Khanna, Jaspreet Kour, Shalini Dhiman, Mohd. Ibrahim, Neerja Sharma, Indu Sharma, Priyanka Sharma, Bilal Ahmad Mir, Renu Bhardwaj, 2023, Chapter 3, 978-3-031-43028-2, 45, 10.1007/978-3-031-43029-9_3 | |
39. | Kuntal Bera, Kakan Ball, Puspendu Dutta, Sanjoy Sadhukhan, 2023, Chapter 7, 978-3-031-43028-2, 147, 10.1007/978-3-031-43029-9_7 | |
40. | Hebat-Allah Ali Hussein, Response Mechanisms of Tolerant and Sensitive Faba Bean (Vicia faba) Cultivars to Nitric Oxide, 2023, 0718-9508, 10.1007/s42729-023-01580-1 | |
41. | Rui Guo, ChangZhao Chen, MengXing He, ZhiWen Li, Yang Lv, XinYu Tao, Qiang Zhang, Kinetin-mediated reduction of cadmium accumulation in rice (Oryza sativa L.) via modulation of cell wall binding capacity in a NO-dependent manner, 2024, 218, 00988472, 105627, 10.1016/j.envexpbot.2023.105627 | |
42. | Gaurav Sharma, Nandni Sharma, Puja Ohri, Harmonizing hydrogen sulfide and nitric oxide: A duo defending plants against salinity stress, 2024, 10898603, 10.1016/j.niox.2024.01.002 | |
43. | Nidhi Kandhol, Vijay Pratap Singh, Sangeeta Pandey, Shivesh Sharma, Lijuan Zhao, Francisco J. Corpas, Zhong-Hua Chen, Jason C. White, Durgesh Kumar Tripathi, Nanoscale materials and NO-ROS homeostasis in plants: trilateral dynamics, 2024, 13601385, 10.1016/j.tplants.2024.06.009 | |
44. | Gonzalo Tortella Fuentes, Paola Fincheira, Olga Rubilar, Sebastian Leiva, Ivette Fernandez, Mauricio Schoebitz, Milena T. Pelegrino, André Paganotti, Roberta Albino dos Reis, Amedea B. Seabra, Nanoparticle-Based Nitric Oxide Donors: Exploring Their Antimicrobial and Anti-Biofilm Capabilities, 2024, 13, 2079-6382, 1047, 10.3390/antibiotics13111047 | |
45. | Diego G. Gomes, Bruno T. Sousa, Joana C. Pieretti, Roney H. Pereira, Wagner R. de Souza, Halley C. Oliveira, Amedea B Seabra, Nanoencapsulated nitric oxide donor triggers a dose-dependent effect on the responses of maize seedlings to high light stress, 2024, 2667064X, 100711, 10.1016/j.stress.2024.100711 | |
46. | Zhenning Teng, Qin Zheng, Yaqiong Peng, Yi Li, Shuan Meng, Bohan Liu, Yan Peng, Meijuan Duan, Dingyang Yuan, Jianhua Zhang, Nenghui Ye, Nitrate reductase–dependent nitric oxide production mediates nitrate-conferred salt tolerance in rice seedlings, 2025, 197, 0032-0889, 10.1093/plphys/kiaf080 | |
47. | Renan S. Nunes, Kelli C. Freitas Mariano, Joana C. Pieretti, Roberta A. dos Reis, Amedea B. Seabra, Innovative nitric oxide-releasing nanomaterials: current progress, trends, challenges, and perspectives in cardiovascular therapies, 2025, 10898603, 10.1016/j.niox.2025.03.004 |