The Effect of Different Forms for the Delay in A Model of the Nephron

  • Received: 01 August 2004 Accepted: 29 June 2018 Published: 01 November 2004
  • MSC : 92C99,37N25,34K60.

  • We investigate how the dynamics of a mathematical model of a nephron depend on the precise form of the delay in the tubuloglomerular feedback loop. Although qualitative behavioral similarities emerge for different orders of delay, we find that significant quantitative differences occur. Without more knowledge of the form of the delay, this places restrictions on how reasonable it is to expect close quantitative agreement between the mathematical model and experimental data.

    Citation: Anne C. Skeldon, Ian Purvey. The Effect of Different Forms for the Delay in A Model of the Nephron[J]. Mathematical Biosciences and Engineering, 2005, 2(1): 97-109. doi: 10.3934/mbe.2005.2.97

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  • We investigate how the dynamics of a mathematical model of a nephron depend on the precise form of the delay in the tubuloglomerular feedback loop. Although qualitative behavioral similarities emerge for different orders of delay, we find that significant quantitative differences occur. Without more knowledge of the form of the delay, this places restrictions on how reasonable it is to expect close quantitative agreement between the mathematical model and experimental data.


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  • © 2005 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
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