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AIMS Neuroscience

2023, Volume 10, Issue 4: 354-375. doi: 10.3934/Neuroscience.2023027
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Research article

Multiple sclerosis and mental health related quality of life: The role of defense mechanisms, defense styles and family environment

  • 1.
    3rd Department of Psychiatry, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
  • 2.
    2nd Department of Neurology, MS Center, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece
  • Received: 09 August 2023 Revised: 13 November 2023 Accepted: 21 November 2023 Published: 27 November 2023

  • Background

    Multiple sclerosis is a demyelinating chronic neurologic disease that can lead to disability and thus to deterioration of quality of life. Psychological parameters such as ego defense mechanisms, defense styles and family environment are important factors in the adaptation process, and as such they can play important roles in QoL. This study aims to assess the psychological factors as well as the clinical and demographic characteristics related to mental health quality of life (MHQoL).

     Methods

    This was an observational, cross-sectional study conducted in a sample of 90 people with MS in the years 2018–2020. All participants completed the following questionnaires: MSQoL-54, DSQ-88, LSI, FES-R, SOC, BDI-II, STAI. Disability was assessed using EDSS.

     Results

    In multiple linear regression, significant roles were played by depression (R2: 41.1%, p: 0.001) and, to a lesser extent, the event of a relapse (R2: 3.5%, p: 0.005), expressiveness (R2: 3.6%, p < 0.05) and image distortion style (R2: 4.5%, p: 0.032). After performing a hierarchical-stepwise analysis (excluding depression), the important factors were maladaptive defense style (R2: 23.7%, p: 0.002), the event of relapse (R2: 8.1%, p < 0.001), expressiveness (R2: 5.5%, p: 0.004) and self-sacrificing defense style (R2: 2.4%, p: 0.071).

     Conclusion

    Psychological factors play important roles in MHQoL of people with multiple sclerosis. Thus, neurologists should integrate in their practice an assessment by mental health specialists. Moreover, targeted psychotherapeutic interventions could be planned i to improve QoL.

    Citation: Anthi Amaslidou, Ioanna Ierodiakonou-Benou, Christos Bakirtzis, Ioannis Nikolaidis, Theano Tatsi, Nikolaos Grigoriadis, Ioannis Nimatoudis. Multiple sclerosis and mental health related quality of life: The role of defense mechanisms, defense styles and family environment[J]. AIMS Neuroscience, 2023, 10(4): 354-375. doi: 10.3934/Neuroscience.2023027

    Related Papers:

  • Background

    Multiple sclerosis is a demyelinating chronic neurologic disease that can lead to disability and thus to deterioration of quality of life. Psychological parameters such as ego defense mechanisms, defense styles and family environment are important factors in the adaptation process, and as such they can play important roles in QoL. This study aims to assess the psychological factors as well as the clinical and demographic characteristics related to mental health quality of life (MHQoL).

     Methods

    This was an observational, cross-sectional study conducted in a sample of 90 people with MS in the years 2018–2020. All participants completed the following questionnaires: MSQoL-54, DSQ-88, LSI, FES-R, SOC, BDI-II, STAI. Disability was assessed using EDSS.

     Results

    In multiple linear regression, significant roles were played by depression (R2: 41.1%, p: 0.001) and, to a lesser extent, the event of a relapse (R2: 3.5%, p: 0.005), expressiveness (R2: 3.6%, p < 0.05) and image distortion style (R2: 4.5%, p: 0.032). After performing a hierarchical-stepwise analysis (excluding depression), the important factors were maladaptive defense style (R2: 23.7%, p: 0.002), the event of relapse (R2: 8.1%, p < 0.001), expressiveness (R2: 5.5%, p: 0.004) and self-sacrificing defense style (R2: 2.4%, p: 0.071).

     Conclusion

    Psychological factors play important roles in MHQoL of people with multiple sclerosis. Thus, neurologists should integrate in their practice an assessment by mental health specialists. Moreover, targeted psychotherapeutic interventions could be planned i to improve QoL.

    Abbreviations

    MS

    multiple sclerosis

         QoL

    quality of life

         PwMS

    people with MS

         MHQoL

    mental health related quality of life

         PHQoL

    physical health related quality of life.
    加载中


    Conflict of interests


    All authors declare no conflicts of interest in this paper.

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