Export file:

Format

  • RIS(for EndNote,Reference Manager,ProCite)
  • BibTex
  • Text

Content

  • Citation Only
  • Citation and Abstract

Effects of facet joint degeneration on stress alterations in cervical spine C5–C6: A finite element analysis

1 Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 201203, China
2 Institute of Traumatology, Shanghai Academy of TCM, Shanghai 201203, China
3 Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY, USA.
4 Yangzhi Rehabilitation Hospital, Sunshine Rehabilitation Centre, Tongji University School of Medicine, Shanghai 201619, China

Special Issues: Microsurgical and Minimal Invasive Technologies for Musculoskeletal Tissue Repair

It has been demonstrated that articular facet degeneration can cause local strain alterations and induce neck pain. This study aims to quantify the biomechanical effects of normal and degenerated C5–C6 articular facets, and evaluate the correlation of mechanical strain between healthy and degenerated spine. A 3-dimensional finite element (FE) model of the C5–C6 cervical spine was developed [Model 0 (M0)]. The asymmetric models of C5–C6 bilateral articular facet joint were established separately to mimic articular facet joint degeneration. The capsule ligament stiffness of C5–C6 unilateral facet joint was altered with minimum and maximum threshold to simulate capsule ligaments’ lesion and calcification [Model 1 (M1) and Model 2 (M2), respectively]. Besides, the cervical C5–C6 unilateral articular facet joint direction was changed by 5° and 10° forward to imitate the moderate joint hyperplasia and severe osteophyte (Model 3 and Model 4 respectively). M1 increased the rotation range of ipsilateral side (left), while M2 reduced, and both had limited effect on the contralateral side (right). The angle increased in Model 3 (M3) (61°) and Model 4 (M4) (55°) comparing to M0 during the axial rotation, and the angle of M4 was larger. M3 and M4 increased the nucleus pulposus pressure with and without controlled angular displacement during axial rotation. The pressure of nucleus pulpous increased during M1 rotating to the abnormal side but decreased when rotating to the other side, but the results of M2 were opposite. The capsule ligament stiffness made an impact on segmental mobility and vertebral spatial position, and the sagittal angle of articular facet joint exerted an influence on disc pressure distribution.
  Figure/Table
  Supplementary
  Article Metrics

Keywords spine stress and strain; spine degeneration; articular facet joint; finite element analysis; osteoporosis; regeneration; mechanical stress alteration

Citation: Huihao Wang, Kuan Wang, Zhen Deng, Xiaofei Li, Yi-Xian Qin, Hongsheng Zhan, Wenxin Niu. Effects of facet joint degeneration on stress alterations in cervical spine C5–C6: A finite element analysis. Mathematical Biosciences and Engineering, 2019, 16(6): 7447-7457. doi: 10.3934/mbe.2019373

References

  • 1. N. Bogduk, The anatomy and pathophysiology of neck pain, Phys. Med. Rehabil. Clin. N. Am., 22 (2011), 367–382. 2. N. Yoganandan, S. Kumaresan and F. A. Pintar, Biomechanics of the cervical spine Part 2. Cervical spine soft tissue responses and biomechanical modeling, Clin. Biomech. (Bristol, Avon), 16 (2001), 1–27.
  • 3. M. Richter, H. J. Wilke, P. Kluger, et al., Load-displacement properties of the normal and injured lower cervical spine in vitro, Eur. Spine J., 9 (2000), 104–108.
  • 4. R. A. Hartman, R. E. Tisherman, C. Wang, et al., Mechanical role of the posterior column components in the cervical spine, Eur. Spine J., 25 (2016), 2129–2138.
  • 5. N. Yoganandan, S. Kumaresan and F. A. Pintar, Geometric and mechanical properties of human cervical spine ligaments. J. Biomech. Eng., 122 (2000), 623–629.
  • 6. S. F. Mattucci, J. A. Moulton, N. Chandrashekar, et al., Strain rate dependent properties of younger human cervical spine ligaments, J. Mech. Behav. Biomed. Mater., 10 (2012), 216–226.
  • 7. D. Steilen, R. Hauser, B. Woldin, et al., Chronic neck pain: Making the connection between capsular ligament laxity and cervical instability, Open Orthop. J., 8 (2014), 326–345.
  • 8. T. Iida, K. Abumi, Y. Kotani, et al., Effects of aging and spinal degeneration on mechanical properties of lumbar supraspinous and interspinous ligaments, Spine J., 2 (2002), 95–100.
  • 9. K. P. Quinn, K. E. Lee, C. C. Ahaghotu, et al., Structural changes in the cervical facet capsular ligament: Potential contributions to pain following subfailure loading, Stapp Car Crash J., 51 (2007), 169–187.
  • 10. G. P. Pal, R. V. Routal and S. K. Saggu, The orientation of the articular facets of the zygapophyseal joints at the cervical and upper thoracic region, J. Anat., 198 (2001), 431–441.
  • 11. X. Rong, Z. Liu, B. Wang, et al., Relationship between facet tropism and facet joint degeneration in the sub-axial cervical spine, BMC Musculoskelet. Disord., 18 (2017), 86.
  • 12. H. Zeng, D. Zou and J. Wu, Helical CT three-dimensional reconstruction for inferior cervical zygapophyseal joint and its clinic meaning, Chi. J. Spine Spinal Cord, 1 (2012), 59–64.
  • 13. R. C. Decker, Surgical treatment and outcomes of cervical radiculopathy, Phys. Med. Rehabil. Clin. N. Am., 22 (2011) 179–191.
  • 14. Z. Cai, Z. Li, J. Dong, et al., A study on protective performance of bullet-proof helmet under impact loading, J. Vibroeng, 18 (2016), 2495–2507.
  • 15. T. Xie, J. Qian, Y. Lu, et al., Biomechanical comparison of laminectomy, hemilaminectomy and a new minimally invasive approach in the surgical treatment of multilevel cervical intradural tumour: a finite element analysis, Eur. Spine J., 22 (2013), 2719–2730.
  • 16. B. D. Stemper, N. Yoganandan and F. A. Pintar, Effects of abnormal posture on capsular ligament elongations in a computational model subjected to whiplash loading, J. Biomech., 38 (2005), 1313–1323.
  • 17. J. D. Hoppenfeld, Cervical facet arthropathy and occipital neuralgia: headache culprits, Curr. Pain Headache Rep., 14 (2010), 418–423.
  • 18. K. Wang, H. Wang, Z. Deng, et al., Cervical traction therapy with and without neck support: A finite element analysis, Musculoskelet. Sci. Pract., 28 (2017), 1–9.
  • 19. Z. B. Friedenberg and W. T. Miller, Degenerative disc disease of the cervical spine, J. Bone Joint Surg. Am., 45 (1963), 1171–1178.
  • 20. Z. Wang, H. Zhao, J. M. Liu, et al., Resection or degeneration of uncovertebral joints altered the segmental kinematics and load-sharing pattern of subaxial cervical spine: a biomechanical investigation using a C2–T1 finite element model, J. Biomech., 49 (2016), 2854–2862.
  • 21. N. Kallemeyn, A. Gandhi, S. Kode, et al., Validation of a C2–C7 cervical spine finite element model using specimen-specific flexibility data, Med. Eng. Phys., 32 (2010), 482–489.
  • 22. M. B. Panzer and D. S. Cronin, C4–C5 segment finite element model development, validation, and load-sharing investigation, J. Biomech., 42 (2009), 480–490.
  • 23. S. F. Mattucci and D. S. Cronin, A method to characterize average cervical spine ligament response based on raw data sets for implementation into injury biomechanics models, J. Mech. Behav. Biomed. Mater., 41 (2015), 251–260.
  • 24. S. H. Lee, Y. J. Im, K. T. Kim, et al., Comparison of cervical spine biomechanics after fixed-and mobile-core artificial disc replacement: a finite element analysis, Spine (Phila Pa 1976), 36 (2011), 700–708.
  • 25. Y. Wu, J. Wu, J. Guan, et al., Study of double-level degeneration of lower lumbar spines by finite element model, World Neurosurg., 86 (2015), 294–299.
  • 26. Z. Mo, Y. Zhao, C. Du, et al., Does location of rotation center in artificial disc affect cervical biomechanics?, Spine (Phila Pa 1976), 40 (2015), 469–475.
  • 27. K. Wang, Z. Deng, H. Wang, et al., Influence of variations in stiffness of cervical ligaments on C5–C6 segment, J. Mech. Behav. Biomed. Mater., 72 (2017), 129–137.
  • 28. S. A. O'Leary, J. M. Link, E. O. Klineberg, et al., Characterization of facet joint cartilage properties in the human and interspecies comparisons. Acta. Biomater., 54 (2017), 367–376.
  • 29. J. Dvorak, J. A. Antinnes, M. Panjabi, et al., Age and gender related normal motion of the cervical spine, Spine (Phila Pa 1976), 17 (1992), 393–398.
  • 30. F. Heuer, H. Schmidt, Z. Klezl, et al., Stepwise reduction of functional spinal structures increase range of motion and change lordosis angle, J. Biomech., 40 (2007), 271–280.
  • 31. K. P. Quinn, K. E. Lee, C. C. Ahaghotu, et al., Structural changes in the cervical facet capsular ligament: Potential contributions to pain following subfailure loading, Stapp Car Crash J., 51 (2007), 169–187.
  • 32. P. D. Leahy and C. M. Puttlitz, The effects of ligamentous injury in the human lower cervical spine, J. Biomech., 45 (2012), 2668–2672.
  • 33. Y. Kotani, P. S. McNulty, K. Abumi, et al., The role of anteromedial foraminotomy and the uncovertebral joints in the stability of the cervical spine, a biomechanical study, Spine (Phila Pa 1976), 23 (1998), 1559–1565.
  • 34. Z. Cai, Z. Li, L. Wang, et al., A three-dimensional finite element modelling of human chest injury following front or side impact loading, J. Vibroeng., 18 (2016), 539–550.

 

Reader Comments

your name: *   your email: *  

© 2019 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

Download full text in PDF

Export Citation

Copyright © AIMS Press All Rights Reserved