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On the way to allergy prevention—future perspective or illusory aim?

1 Chair and Institute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München - German Research Center for Environmental Health, Augsburg, Germany
2 CK-CARE, Christine Kühne - Center for Allergy Research and Education, Davos, Switzerland

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1. Bieber T, Akdis C, Lauener R, et al. (2016) Global allergy forum and 3rd davos declaration 2015: atopic dermatitis/eczema: challenges and opportunities toward precision medicine. Allergy 71: 588–592.    

2. Ring J (2012) Davos declaration: allergy as a global problem. Allergy 67: 141–143.    

3. Schaub B, Lauener R, Von ME (2006) The many faces of the hygiene hypothesis. J Allergy Clin Immun 117: 969–977.    

4. Roduit C, Wohlgensinger J, Frei R, et al. (2011) Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis. J Allergy Clin Immun 127: 179–185.    

5. Gilles S, Mariani V, Bryce M, et al. (2009) Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immune systems towards a T(H)2-dominated response. Allergy Asthma Cl Im 5: 3–8.    

6. Wimmer M, Alessandrini F, Gilles S, et al. (2015) Pollen-derived adenosine is a necessary cofactor for ragweed allergy. Allergy 70: 944–954.    

7. Traidl-Hoffmann C, Jakob T, Behrendt H (2009) Determinants of allergenicity. J Allergy Clin Immun 123: 558–566.    

8. Gilles S, Fekete A, Zhang X, et al. (2011) Pollen metabolome analysis reveals adenosine as a major regulator of dendritic cell-primed T(H) cell responses. J Allergy Clin Immun 127: 1–9.    

9. Papadopoulos NG, Agache I, Bavbek S, et al. (2012) Research needs in allergy: an EAACI position paper, in collaboration with EFA. Clin Transl Allergy 2: 21–45.    

10. Cecchi L, D'Amato G, Ayres JG, et al. (2010) Projections of the effects of climate change on allergic asthma: the contribution of aerobiology. Allergy 65: 1073–1081.

11. Damialis A, Kaimakamis E, Konoglou M, et al. (2017) Estimating the abundance of airborne pollen and fungal spores at variable elevations using an aircraft: how high can they fly? Sci Rep 7: 44535–44545.    

12. Buters JT, Kasche A, Weichenmeier I, et al. (2008) Year-to-year variation in release of Bet v 1 allergen from birch pollen: evidence for geographical differences between West and South Germany. Int Arch Allergy Imm 145: 122–130.

13. Jochner S, Markevych I, Beck I, et al. (2015) The effects of short-and long-term air pollutants on plant phenology and leaf characteristics. Environ Pollut 206: 382–389.    

14. Beck I, Jochner S, Gilles S, et al. (2013) High environmental ozone levels lead to enhanced allergenicity of birch pollen. Plos One 8: e80147–e80153.    

15. Obersteiner A, Gilles S, Frank U, et al. (2016) Pollen-associated microbiome correlates with pollution parameters and the allergenicity of pollen. Plos One 11: e0149545–e0149560.    

16. von Mutius E (2016) The microbial environment and its influence on asthma prevention in early life. J Allergy Clin Immun 137: 680–689.    

17. Xing H, Goedert JJ, Pu A, et al. (2016) Allergy associations with the adult fecal microbiota: analysis of the American gut project. Ebiomedicine 3: 172–179.    

18. Kong HH, Andersson B, Clavel T, et al. (2017) Performing skin microbiome research: a method to the madness. J Invest Dermatol 137: 561–568.    

19. Kong HH, Segre JA (2017) The molecular revolution in cutaneous biology: investigating the skin microbiome. J Invest Dermatol 137: e119–e122.    

20. Eyerich K, Pennino D, Scarponi C, et al. (2009) IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immun 123: 59–66.    

21. Lehtimäki J, Karkman A, Laatikainen T, et al. (2017) Patterns in the skin microbiota differ in children and teenagers between rural and urban environments. Sci Rep 7: 45651–45661.    

22. Peters EM (2016) Stressed skin?-a molecular psychosomatic update on stress-causes and effects in dermatologic diseases. J Dtsch Dermatol Ges 14: 233–252.

23. Peters EMJ, Michenko A, Kupfer J, et al. (2014) Mental stress in atopic dermatitis-neuronal plasticity and the cholinergic system are affected in atopic dermatitis and in response to acute experimental mental stress in a randomized controlled pilot study. Plos One 9: 1–17.

24. Ring J, Akdis C, Lauener R, et al. (2014) Global allergy forum and second davos declaration 2013 allergy: barriers to cure-challenges and actions to be taken. Allergy 69: 978–982.    

Copyright Info: © 2017, Claudia Traidl-Hoffmann, licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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