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Qualitative theoretical modeling to study the possibility of detecting multi-virus in blood flow using Nano-quartz crystal microbalance

1 Electrical Engineering Department, College of Engineering, King Khalid University, Asir 61421, Saudi Arabia
2 Department of Mechanical Engineering, College of Engineering, King Khalid University, Asir 61421, Saudi Arabia
3 Department of Computers and Communications, College of Engineering, Delta University for Science and Technology, Egypt
4 Laboratory of Electromechanical Systems (LASEM), National Engineering School of Sfax, University of Sfax, Sfax 43038, Tunisia
5 Electronics and Information Technology Laboratory, University of Sfax, National Engineering School of Sfax, Sfax 43038, Tunisia
6 Research Center for Advanced Materials Science (RCAMS), King Khalid University, Asir 61413, Saudi Arabia.
7 Nabeul’s Foundation Institute for Engineering Studies, University of Carthage, IPEIN, Nabeul 8000, Tunisia

Methods for testing the presence of a virus in the blood are of interest to researchers and doctors because they determine how rapidly a virus is detected. In general, virus detection is a major scientific problem due to the serious effects of viruses on the human body. At present, only one virus can be detected in a single test. This potentially costs the medical establishment more time and money that could be saved if blood testing was more efficient. This study presents a qualitative method to enable doctors and researchers to detect more than one virus simultaneously. This was performed using quartz nanoparticles. Using polymer thin films of polydimethylsiloxane (PDMS), each chip emits a different frequency for each specific type of virus on the chip. The multiplicity of these chips allows for the detection of a number of viruses with the same number of nanoscale chips simultaneously. Blood flow around quartz nanoparticles was modelled. In this model, several conventional Quartz Crystal Microbalance (QCM) with nanostructures (Nano-QCM) particles are inserted into the three main types of blood vessels. The results showed that the best location for the Nano-QCM is the large artery and that it is possible to test for a number of viruses in all types of blood vessels.
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© 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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