Integrative Cardiology—State of the art of Mind Body Therapies for the treatment of Cardiovascular Disease and risk factors

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Guest Editor
Carlo Dal Lin
Dept. of Cardiologic, Thoracic and Vascular Sciences, Padua University School of Medicine, Italy

Manuscript Topics
Psychological stress determines the hypothalamic-pituitary-adrenocortical and sympatho-adrenomedullary axes activation and nowadays represents a pivotal cardiovascular risk factor. Epidemiological data show that acute or chronic stress impair coronary microcirculation feeding atherosclerosis and leading to myocardial ischemia and coronary heart disease (CHD). Loneliness, social isolation and work-related stress increase the risk of a first CHD event. Moreover, emotional stress can trigger arrhythmias and sudden death among individuals with advanced atherosclerosis. A stress-specific coronary syndrome, known as transient left ventricular apical ballooning cardiomyopathy or stress (Takotsubo) cardiomyopathy, also exists. Among patients with CHD, long-term stress can increase the risk of recurrent CHD events and mortality. Understanding of stress as a risk factor and the use of stress management in the clinical settings have been relatively limited, although the importance of stress management is highlighted by the American Heart Association and in European guidelines for cardiovascular disease prevention. In this special issue we aim to describe the state of the art in the field of mind-body therapies that could effectively be integrated in the current clinical practice for treatment of cardiovascular disorders and risk factors. We are looking for practical and non-dispersive papers focusing both on therapies and their physiologic background.

• Brain-heart cross-talk: how brain and heart dialogue?
• How stress affects the heart? Th role of hormones, cytokines, neurotransmitters
• Psychologic traits and personalities and heart vulnerability
• Mental stress induced myocardial ischemia
• Mental stress leads to cellular oxidative stress and to the misfolding of proteins
• Epigenetics and heart disease. Stress can be transmitted transgenerationally through epigenetic signatures

Therapy (mechanisms and effects on cardiovascular disease or its risk factors)
• Psychotherapy
• Meditation
• Biofeedback
• Music
• Massage and manipulation (Shitasu, Ayurveda, Tuina, Ostheopathy)
• Breathing
• Yoga

Paper submission
All manuscripts will be peer-reviewed before their acceptance for publication.
The deadline for manuscript submission is 30th August 2017.

Instruction for Authors
Please submit your manuscript to online submission system

Bernardo Lopez Abel, María I Martínez-Soto, Maria Luz Couce
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