Basal Ganglia: Function and Dysfunction

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Guest Editor
Dr. Zhiming Zhang
University of Kentucky College of Medicine, Lexington, Kentucky, USA.

Manuscript Topics
The basal ganglia are a group of subcortical nuclei inside the brain and responsible primarily for motor control, as well as motor learning, executive function and emotions. So, basal ganglia dysfunctions are linked with many brain disorders such as dystonia, Huntington disease, Parkinson’s disease, Multiple system atrophy, Progressive supranuclear palsy and Wilson disease in particular. Although those disorders are well known and studied in community of both basic and clinic neuroscience, few tools or treatments have been available for physicians to manage and treat the complex disorders yet. Probably, the deep brain stimulation (DBS) is only one highly recommended for both hypo- and hyperkinetic movement disorders of basal ganglia region such as Parkinson's disease and dystonia. Therefore, there is an increasing trend to attempt to treat those disorders with interdisciplinary approaches. It has been proved that along with deeper understanding of how the basal ganglia operate, researchers from various fields will provide novel promising avenues for management and treatment for basal ganglia dysfunctions related disorders. Up to date, a great line of scientific evidence supports a range of non-surgical and non-pharmacological interventions for Parkinson’s disease and other movement disorders.

According to available information from PubMed, more than 30,000 peer reviewed articles, based on key words: basal ganglia disorders and basal ganglia disorder treatment, have been published during the past 5-year period. However, there are still lacking pragmatic methods to effectively manage basal ganglia disorders unarguably. In order to promote more novel treatments, the potential topics for this special issue will include but are not limited to: novel non-surgical and/or non-pharmaceutic methods such as acupuncture and natural remedy, complementary physical therapy and occupational therapy, and other creative natural, safe and effective ways to manage those disorders.

Paper submission
All manuscripts will be peer-reviewed before their acceptance for publication.
The deadline for manuscript submission is 31st August 2019.

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T. Virmani, F. J. Urbano, V. Bisagno, E. Garcia-Rill
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