The increasing lifespan of women and their extended time spent in menopause pose significant challenges for health care systems, primarily due to the impacts of postmenopausal estrogen deficiency and aging on health. Menopause's onset is linked to a heightened prevalence of obesity, metabolic syndrome, cardiovascular disease, and osteoporosis. Diet is particularly relevant during menopause given its impact on quality of life and longevity and its modifiability. Because the Mediterranean diet is currently regarded as one of the healthiest dietary models in the world, the aim of this systematic review was to assess current evidence regarding the effectiveness of studies on the Mediterranean diet as an intervention for menopausal women. A systematic review of intervention-based studies involving the Mediterranean diet among menopausal women was performed in Scopus, PubMed, and Web of Science. The results of seven that met the inclusion criteria suggests that adherence to the Mediterranean diet can have beneficial impacts on menopausal women's health, including reductions in weight, blood pressure, blood ω6: ω3 ratio, triglycerides, total cholesterol, and LDL levels. Those results seem to be relevant for public health interventions aimed at improving menopausal women's quality of life.
Citation: Carla Gonçalves, Helena Moreira, Ricardo Santos. Systematic review of mediterranean diet interventions in menopausal women[J]. AIMS Public Health, 2024, 11(1): 110-129. doi: 10.3934/publichealth.2024005
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The increasing lifespan of women and their extended time spent in menopause pose significant challenges for health care systems, primarily due to the impacts of postmenopausal estrogen deficiency and aging on health. Menopause's onset is linked to a heightened prevalence of obesity, metabolic syndrome, cardiovascular disease, and osteoporosis. Diet is particularly relevant during menopause given its impact on quality of life and longevity and its modifiability. Because the Mediterranean diet is currently regarded as one of the healthiest dietary models in the world, the aim of this systematic review was to assess current evidence regarding the effectiveness of studies on the Mediterranean diet as an intervention for menopausal women. A systematic review of intervention-based studies involving the Mediterranean diet among menopausal women was performed in Scopus, PubMed, and Web of Science. The results of seven that met the inclusion criteria suggests that adherence to the Mediterranean diet can have beneficial impacts on menopausal women's health, including reductions in weight, blood pressure, blood ω6: ω3 ratio, triglycerides, total cholesterol, and LDL levels. Those results seem to be relevant for public health interventions aimed at improving menopausal women's quality of life.
Differential equations with various types of fractional derivatives such as Caputo fractional derivative, Riemann-Liouville fractional derivative, are intensively studied theoretically and applied to varies models in the last decades. For example, they are successfully applied to study various types of neural networks (see, for example, [1,2,3]). Fractional differential equations with delays are rapidly developed. One of the main studied qualitative questions about fractional delay differential equation is the one about stability. In 1961, Dorato [4] introduced a concept of finite time stability (FTS). FTS is different from asymptotic stability. However, it is regarded as one of the core problems in delay systems from practical considerations. Later this type of stability has been applied to different types of differential equations. Recently, it is applied for Caputo delta fractional difference equations [5,6], for Caputo fractional differential equations [7] for -Hilfer fractional differential equation [8].
The investigations of the properties of the solutions of Riemann-Liouville (RL) fractional differential equations with delays are still at his initial stage. The asymptotic stability of the zero solution of the linear homogeneous differential system with Riemann-Liouville fractional derivative is studied in [9]. Li and Wang introduced the concept of a delayed Mittag-Leffler type matrix function, and then they presented the finite-time stability results by virtue of a delayed Mittag-Leffler type matrix in [10,11,12]. In connection with the presence of the bounded delay the initial condition is given on a whole finite interval called initial interval. In the above mentioned papers ([10,11,12]) the authors study the case when the lower limit of the RL fractional derivative coincides with the left side end of the initial interval. It changes the meaning of the initial condition in differential equations. In connection with this in the paper we set up an initial condition satisfying two main properties: first, it is similar to the initial condition in differential equations with ordinary derivatives and, second, the RL fractional condition is defined at the right side end of the initial interval which is connected with the presence of RL fractional derivative.
In this paper we study initial value problems for scalar nonlinear RL fractional differential equations with constant delays. Similarly to the case of ordinary derivative, the differential equation is given to the right of the initial time interval. It requires the lower bound of the RL fractional derivative to coincides with the right side end of the initial time interval. We present an integral representation of of the studied initial value problem. By the help of fractional generalization of Gronwall inequality we study the existence, continuous dependence and finite time stability of the scalar nonlinear RL fractional differential equations.
The main contributions of the current paper include:
(ⅰ) An appropriate initial value problem for nonlinear RL fractional differential equations is set up based on the idea of the initial time interval for delay differential equations with ordinary derivatives.
(ⅱ) A mild solution of the considered initial value problem is defined based on an appropriate integral representation of the solution.
(ⅲ) The existence, continuous dependence and finite time stability of the scalar nonlinear RL fractional differential equations is studied by the help of fractional generalization of Gronwall inequality.
The rest of this paper is organized as follows. In Section 2, some notations and preliminary lemmas are presented. In Section 3, main results are obtained. In Section 3.1. mild solution of the studied initial value problem is defined and some sufficient conditions by Banach contraction principle are obtained. In Section 3.2. continuous dependence on the initial functions is investigated based on the fractional extension of Gronwall inequality. In Section 3.3. some sufficient conditions for finite time stability are given.
Let J=[−τ,T], I=[0,T] where τ>0 is a constant, T<∞. Without loss of generality we can assume there exists a natural number N such that T=(N+1)τ. Let Lloc1(I,R) be the linear space of all locally Lebesgue integrable functions m:I→R, PC(J)=C([−τ,0),R)∪C((0,T],R).
Let x∈PC(J,R). Denote ||x||J=supt∈J|x(t)|.
In this paper we will use the following definitions for fractional derivatives and integrals:
− Riemann - Liouville fractional integral of order q∈(0,1) ([13,14])
0Iqtm(t)=1Γ(q)t∫0m(s)(t−s)1−qds, t∈I, |
where Γ(.) is the Gamma function.
−Riemann - Liouville fractional derivative of order q∈(0,1) ([13,14])
RL0Dqtm(t)=ddt( 0I1−qtm(t))=1Γ(1−q)ddtt∫0(t−s)−qm(s)ds, t∈I. |
We will give fractional integrals and RL fractional derivatives of some elementary functions which will be used later:
Proposition 1. The following equalities are true:
RL0Dqttβ=Γ(1+β)Γ(1+β−q)tβ−q, 0I1−qtβ−1=Γ(β)Γ(1+β−q)tβ−q, |
0I1−qtq−1=Γ(q), RL0Dqttq−1=0. |
The definitions of the initial condition for fractional differential equations with RL-derivatives are based on the following result:
Proposition 2. (Lemma 3.2 [15]). Let q∈(0,1), and m∈Lloc1([0,T],R).
(a) If there exists a.e. a limit limt→0+[tq−1m(t)]=c, then there also exists a limit
0I1−qtm(t)|t=0:=limt→0+ 0I1−qtm(t)=cΓ(q). |
(b) If there exists a.e. a limit 0I1−qtm(t)|t=0=b and if there exists the limit limt→0+[t1−qm(t)] then
limt→0+[t1−qm(t)]=bΓ(q). |
We will use the Mittag - Leffler functions with one and with two parameters, respectively, (see, for example, [14]) given by Ep(z)=∑∞j=0zjΓ(jp+1) and Ep,q(z)=∑∞j=0zjΓ(jp+q).
Proposition 3. [16] (Gronwall fractional inequality) Suppose a(t) is a nonnegative function locally integrable on [0,T) (some T≤∞) and b(t) is a nonnegative, nondecreasing continuous function defined on [0,T), b(t)≤M (constant), and suppose u(t) is nonnegative and locally integrable on [0,T) with
u(t)≤a(t)+b(t)∫t0(t−s)q−1u(s)ds, t∈[0,T). |
Then
u(t)≤a(t)+∫t0(∞∑n=1(b(t)Γ(q))nΓ(nq)(t−s)nq−1a(s))ds, t∈[0,T). |
Recently, in [17] the non-homogeneous scalar linear Riemann-Liouville fractional differential equations with a constant delay :
RL0Dqtx(t)=Ax(t)+Bx(t−τ)+f(t) for t>0. | (2.1) |
with the initial conditions
x(t)=g(t), t∈[−τ,0], | (2.2) |
limt→0+(t1−qx(t))=g(0)Γ(q) | (2.3) |
where f∈C(R+,R), g∈C([−τ,0],R) was studied. It was proved the solution is given by the function
Λq(t)={g(t)t∈(−τ,0]g(0)Eq,q(Atq)tq−1+∫t0(t−s)q−1Eq,q(A(t−s)q)(Bg(s−τ)+f(s))ds t∈(0,τ]g(0)Eq,q(Atq)tq−1+∫t0(t−s)q−1Eq,q(A(t−s)q)f(s)ds +Bn−1∑i=0∫(i+1)τiτ(t−s)q−1Eq,q(A(t−s)q)Λq(s−τ)ds +B∫tnτ(t−s)q−1Eq,q(A(t−s)q)Λq(s−τ)ds for t∈(nτ,(n+1)τ],n=1,2,… | (2.4) |
where Eq,q(z)=∑∞i=0ziΓ(iq+q) and Eq(z)=∑∞i=0ziΓ(iq+1) are Mittag-Leffler functions with two and one parameter, respectively.
Now, we will study the following nonlinear fractional delay differential equations
RL0Dqtx(t)=Ax(t)+Bx(t−τ)+f(t,x(t)) for t∈I. | (2.5) |
with the initial conditions (2.2), (2.3) where A,B∈R are given constants, f:I×R→R.
Remark 1. Note that in the case of the linear equation (2.1) we have formula (2.4) for the explicit solution since in the case of nonlinear equation (2.5) we are not able to obtain an explicit formula, we could provide only an integral presentation of the solution (see Example 1 and Example 2).
Example 1. Consider the special case of (2.1):
RL0D0.5tx(t)=x(t−1)+t for t>0x(t)=t, t∈[−1,0],limt→0+(t0.5x(t))=0. | (2.6) |
Then applying Eq,q(0)=1Γ(q) we obtain the solution of (2.6):
x(t)={t, t∈(−1,0]1√π∫t0(t−s)−0.5(s−1+s)ds=2√t√π(43t−1), t∈(0,1]1√π∫t0(t−s)−0.5sds+1√π∫10(t−s)−0.5(s−1)ds+1√π∫tτ(t−s)−0.5x(s−1)ds =43√πt1.5−43√π(t−1)1.5+43√π√t(t−1.5)+t(t−1)+43π√t 2F1[0.5,1.5,2.5,1t] −1615π√t 2F1[0.5,2.5,3.5,1t], t∈(1,2]. | (2.7) |
In connection with Remark 1 we will define a mild solution:
Definition 1. A function x∈PC(J,R) is called a mild solution of the IVP (2.5), (2.2), (2.3) if it satisfies the following integral equation
x(t)={g(t) for t∈[−τ,0],g(0)Eq,q(Atq)tq−1+B∫t0(t−s)q−1Eq,q(A(t−s)q)g(s−τ)ds +∫t0(t−s)q−1Eq,q(A(t−s)q)f(s,x(s))ds for t∈(0,τ],g(0)Eq,q(Atq)tq−1+∫t0(t−s)q−1Eq,q(A(t−s)q)f(s,x(s))ds +Bn−1∑i=0∫(i+1)τiτ(t−s)q−1Eq,q(A(t−s)q)x(s−τ)ds +B∫tnτ(t−s)q−1Eq,q(A(t−s)q)x(s−τ)ds for t∈(nτ,(n+1)τ],n=1,2,…,N |
Example 2. Consider the partial case of (2.5) (compare with (2.6):
RL0D0.5tx(t)=x(t−1)+sin(x(t)) for t>0x(t)=t, t∈[−1,0],limt→0+(t0.5x(t))=0. | (3.1) |
Now similarly to Example 1 we are not able to obtain the exact solution of (2.6). But using Definition 1 we can consider the mild solution x(t) of the IVP (3.1) satisfying:
x(t)={t, t∈(−1,0]1√π∫t0(t−s)−0.5(s−1)ds+1√π∫t0(t−s)−0.5sin(x(s))ds =2√t√π(23t−1)+1√π∫t0(t−s)−0.5sin(x(s))ds, t∈(0,1]1√π∫t0(t−s)−0.5sin(x(s))ds+1√π∫10(t−s)−0.5(s−1)ds+1√π∫tτ(t−s)−0.5x(s−1)ds =1√π∫t0(t−s)−0.5sin(x(s))ds−43√π(t−1)1.5+43√π√t(t−1.5) +1√π∫tτ(t−s)−0.5x(s−1)ds, t∈(1,2]. | (3.2) |
Examples 1 and 2 show the main difference between the linear RL fractional differential equations and the nonlinear RL fractional differential equations with a linear part.
We will introduce the following conditions:
(A1). The function f∈C([0,T]×R,R) and there exists a function w∈C(I,R+) such that |f(t,x)|≤w(t) for all t∈I,x∈R.
(A2). The function f∈C([0,T]×R,R) and there exists a constant L>0 such that |f(t,x)−f(t,y)|≤L|x−y| for all t∈I,x,y∈R. First, we will consider the case of Lipschitz nonlinear function.
Theorem 1. Let A≠0, the condition (A2) be satisfied and
1. The function g∈C([τ,0],R and |g(0)|<∞.
2. ρ=Lh1+|B|h2|A|<1 where h1=maxt∈[0,T]|Eq(Atq)−1|,
h2=maxn=0,1,2,…,N{maxt∈(nτ,(n+1)τ](|Eq(A(t−nτ)q)−1|+n−1∑j=0|Eq(A(t−jτ)q)−Eq(A(t−(j+1)τ)q)|)}. |
Then the the IVP (2.5), (2.2), (2.3) has a unique mild solution x∈PC(J,R).
P r o o f: Existence. Define the operator Ξ:PC(J,R)→PC(J,R) by the equality
Ξ(x(t))={g(t) t∈[−τ,0]g(0)Eq,q(Atq)tq−1+B∫t0(t−s)q−1Eq,q(A(t−s)q)g(s−τ)ds +∫t0(t−s)q−1Eq,q(A(t−s)q)f(s,x(s))ds for t∈(0,τ],g(0)Eq,q(Atq)tq−1+∫t0(t−s)q−1Eq,q(A(t−s)q)f(s,x(s))ds +Bn−1∑i=0∫(i+1)τiτ(t−s)q−1Eq,q(A(t−s)q)x(s−τ)ds +B∫tnτ(t−s)q−1Eq,q(A(t−s)q)x(s−τ)ds for t∈(nτ,(n+1)τ],n=1,2,…,N |
Let z,y∈PC(J,R). We will prove that
|Ξ(z(t))−Ξ(y(t))|≤(L|Eq(Atq)−1||A|+|B|∑n−1j=0|Eq(A(t−jτ)q)−Eq(A(t−(j+1)τ)q)||A| +|B||Eq(A(t−nτ)q)−1||A|)||z−y||J for t∈(nτ,(n+1)τ], n=0,1,2,…,N | (3.3) |
Let t∈(0,τ]. Then applying Definition 1 and the equality
∫t0(t−s)q−1Eq,q(A(t−s)q)ds=∞∑i=0AiΓ((i+1)q)∫t0(t−s)(i+1)q−1ds=∞∑i=0Ai(1+i)qΓ((i+1)q)t(i+1)q=Eq(Atq)−1A, t∈(0,τ], | (3.4) |
we obtain
|Ξ(z(t))−Ξ(y(t))|≤|∫t0(t−s)q−1Eq,q(A(t−s)q)|f(s,z(s))−f(s,y(s))|ds|≤L|∫t0(t−s)q−1Eq,q(A(t−s)q)|z(s)−y(s)|ds|≤L||z−y||J|∫t0(t−s)q−1Eq,q(A(t−s)q)ds|=L|Eq(Atq)−1||A|||z−y||J | (3.5) |
Let t∈(τ,2τ]. Then according to Definition 1 and the equality
∫tτ(t−s)q−1Eq,q(A(t−s)q)ds=∞∑i=0AiΓ((i+1)q)∫tτ(t−s)(i+1)q−1ds=∞∑i=0Ai(1+i)qΓ((i+1)q)(t−τ)(i+1)q=Eq(A(t−τ)q)−1A, t∈(τ,2τ], | (3.6) |
we have
|Ξ(z(t))−Ξ(y(t))|≤|∫t0(t−s)q−1Eq,q(A(t−s)q)|f(s,z(s))−f(s,t(s))|ds| +|B| |∫τ0(t−s)q−1Eq,q(A(t−s)q)|z(s−τ)−y(s−τ)|ds| +|B| |∫tτ(t−s)q−1Eq,q(A(t−s)q)|z(s−τ)−y(s−τ)|ds|≤(L|Eq(Atq)−1|A+|B| |∫tτ(t−s)q−1Eq,q(A(t−s)q)ds|)||z−y||J≤(L|Eq(Atq)−1||A|+|B||Eq(A(t−τ)q)−1||A|)||z−y||J. | (3.7) |
Let t∈(2τ,3τ]. Then according to Definition 1 and the equalities
∫t2τ(t−s)q−1Eq,q(A(t−s)q)ds=∞∑i=0AiΓ((i+1)q)∫t2τ(t−s)(i+1)q−1ds=∞∑i=0Ai(1+i)qΓ((i+1)q)(t−τ)(i+1)q=Eq(A(t−2τ)q)−1A, t∈(2τ,3τ], | (3.8) |
and
∫2ττ(t−s)q−1Eq,q(A(t−s)q)ds=∞∑i=0AiΓ((i+1)q)∫2ττ(t−s)(i+1)q−1ds=∞∑i=0Ai(1+i)qΓ((i+1)q)(t−τ)(i+1)q−∞∑i=0Ai(1+i)qΓ((i+1)q)(t−2τ)(i+1)q=Eq(A(t−τ)q)−Eq(A(t−2τ)q)A, | (3.9) |
we have
|Ξ(z(t))−Ξ(y(t))|≤|∫t0(t−s)q−1Eq,q(A(t−s)q)|f(s,z(s))−f(s,t(s))|ds| +|B| |∫τ0(t−s)q−1Eq,q(A(t−s)q)|z(s−τ)−y(s−τ)|ds| +|B| |∫2ττ(t−s)q−1Eq,q(A(t−s)q)|z(s−τ)−y(s−τ)|ds| +|B| |∫t2τ(t−s)q−1Eq,q(A(t−s)q)|z(s−τ)−y(s−τ)|ds|≤(L|Eq(Atq)−1||A|+|B| |∫2ττ(t−s)q−1Eq,q(A(t−s)q)ds| +|B| |∫t2τ(t−s)q−1Eq,q(A(t−s)q)ds|)||z−y||J≤(L|Eq(Atq)−1||A|+|B||Eq(A(t−τ)q)−Eq(A(t−2τ)q)||A| +|B||Eq(A(t−2τ)q)−1||A|)||z−y||J. | (3.10) |
Following the induction process and the definition of ρ we obtain that ||Ξ(z(t))−Ξ(y(t))||J≤ρ||z−y||J. Therefore, the operator Ξ:PC(J,R)→PC(J,R) is a contraction.
Uniqueness. Let z(t),y(t) be two mild solutions of the IVP (2.5), (2.2), (2.3). Applying induction process w.r.t. the intervals and from condition 2 we obtain that ||z−y||(kτ,(k+1)τ]<ρ||z−y||(kτ,(k+1)τ] for k=0,1,…,N which proves the uniqueness.
Remark 2. It is obvious that the condition A≠0 in Theorem 1 is not a restriction because the nonzero term Ax could be added to the nonlinear part without losing the Lipschitz property.
Example 3. Consider the IVP (3.1) In this case A=0.1,f(t,x)=sin(x)−0.1x,B=1. Then the condition (A2) is satisfied with L=1.1 but the condition 2 of Theorem 1 is not satisfied.
Now, we change the equation in the IVP (3.1) to RL0D0.5tx(t)=0.1x(t−1)+0.01sin(x(t)). In this case A=0.1,f(t,x)=0.01sin(x)−0.1x,B=0.1, h1=h2=0.43581 and ρ=(0.11+0.1)0.435810.1<1. According to Theorem the IVP (3.1) has unique mild solution which is satisfying the integral presentation given in Definition 1.
In the case of a bounded nonlinear function we have the following result:
Theorem 2. Let the condition (A1) be satisfied and
1. The function g∈C([τ,0],R and |g(0)|<∞.
2. ρ=2||w||Ih1+|B|h2|A|<1 where h1 and h2 are defined in Theorem 1.
Then the the IVP (2.5), (2.2), (2.3) has a unique solution x∈PC(J,R).
The proof of Theorem 2 is similar to the one of Theorem 1 and we omit it.
We will study the continuous dependence of mild solutions of the IVP (2.5), (2.2), (2.3) on the initial functions.
Consider IVP (2.5), (2.2), (2.3) and the RL fractional equation (2.5) with initial conditions
x(t)=p(t), t∈[−τ,0], | (3.11) |
limt→0+(t1−qx(t))=p(0)Γ(q) | (3.12) |
Theorem 3. Let the following conditions be satisfied:
1. The functions g,p∈C([−τ,0],R, |g(0)|<∞, |p(0)|<∞.
2. The function f∈C([0,T]×R,R) and it is Lipschitz with a constant L>0 on [0,T]×R.
Then for any number δ>0 there exist numbers Kk,Ck>0, k=0,1,2,…,N such that the inequality ||g−p||[−τ,0]<δ implies
|x(t)−y(t)|≤δ(Kk(t−kτ)q−1+Ck) for t∈(kτ,(k+1)τ], k=0,1,2,…,N | (3.13) |
where x(t),y(t) are mild solutions of the IVPs (2.5), (2.2), (2.3) and (2.5), (3.11), (3.12) respectively.
P r o o f: We will use the induction w.r.t. the intervals to prove the claim.
Let M=supt∈J|Eq,q(Atq)|.
Let t∈(0,τ]. Then from Definition 1 and Eq. (3.4) we get
|x(t)−y(t)|≤δMtq−1+|B|Mδ∫t0(t−s)q−1ds+LM∫t0(t−s)q−1|x(s)−y(s)|ds≤δMtq−1+δM|B|τqq+LM∫t0(t−s)q−1|x(s)−y(s)|ds≤δMtq−1+δP0+LM∫t0(t−s)q−1|x(s)−y(s)|ds | (3.14) |
where P0=M|B|τqq.
According to Proposition 3, the inequality ∫t0(t−s)nq−1sq−1ds=tnq+q−1Γ(q)Γ(nq)Γ(nq+q) we obtain
|x(t)−y(t)|≤δMtq−1+δP0+δP0∫t0∞∑n=1(MLΓ(q))n(t−s)nq−1Γ(nq)ds+δM∫t0∞∑n=1(MLΓ(q))n(t−s)nq−1Γ(nq)sq−1ds≤δP0∞∑n=0(MLΓ(q))ntnqΓ(nq+1)+δMtq−1Γ(q)∞∑n=0(MLΓ(q))n tnqΓ(nq+q)=δ(K0tq−1+C0), t∈(0,τ] | (3.15) |
where K0=MΓ(q)Eq,q(MLΓ(q)τq), C0=M|B|τqqEq(MLΓ(q)τq).
Let t∈(τ,2τ]. Then applying Definition 1, (3.15), the inequalities ∫τ0(τ−s)q−1sq−1ds=τ2q−1Γ(q)Γ(q)Γ(2q), qΓ2(q)Γ(2q)≤2 we get
|x(t)−y(t)|≤δMtq−1+LM∫t0(t−s)q−1|x(s)−y(s)|ds+|B|δM∫τ0(t−s)q−1ds+|B|M∫tτ(t−s)q−1(δK0(s−τ)q−1+δC0)ds≤δMτq−1+LMδK0(t−τ)2q−1Γ2(q)Γ(2q)+LMδC0(2τ)qq+|B|δMτqq+δ|B|MK0(t−τ)2q−1Γ2(q)Γ(2q)+δ|B|MC0(t−τ)qq+LM∫tτ(t−s)q−1|x(s)−y(s)|ds≤δMτq−1+2δ(L+|B|)MK0(t−τ)q−1(τ)qq+δ|B|MC0τqq+|B|δM(τ)qq+δLMK0τ2q−1Γ(q)Γ(q)Γ(2q)+LM∫tτ(t−s)q−1|x(s)−y(s)|ds≤2δ|B|MK0τqq(t−τ)q−1+δP1+LM∫tτ(t−s)q−1|x(s)−y(s)|ds | (3.16) |
where P1=Mτq−1+|B|MC0τqq+|B|M(τ)qq+LMK0τ2q−1Γ(q)Γ(q)Γ(2q).
According to Proposition 3 we obtain
|x(t)−y(t)|≤2|B|MK0τqq(t−τ)q−1+P1++∫tτ[∞∑n=1(MLΓ(q))n(t−s)nq−1Γ(nq)(2|B|MK0τqq(s−τ)q−1+P1]ds≤2|B|MK0τqq(t−τ)q−1+P1Eq(MLΓ(q)(t−τ)q)+2|B|MK0τqq∞∑n=1(MLΓ(q))n(t−τ)−1+q+nqΓ(q)Γ(nq+q)≤P1Eq(MLΓ(q)(t−τ)q)+2|B|MK0Γ(q)τqq(t−τ)q−1Eq,q(MLΓ(q)(t−τ)q)≤P1Eq(MLΓ(q)τq)+2|B|MK0Γ(q)τqq(t−τ)q−1Eq,q(MLΓ(q)τq)=δ(K1(t−τ)q−1+C1), t∈(τ,2τ] | (3.17) |
where K1=2|B|M2Γ2(q)E2q,q(MLΓ(q)τq)τqq and C1=P1Eq(MLΓ(q)τq).
Let t∈(2τ,3τ]. Then applying Definition 1 and (3.6) we get
|x(t)−y(t)|≤δMtq−1+LMδ∫τ0(t−s)q−1(K0sq−1+C0)ds+LMδ∫2ττ(t−s)q−1(K1(s−τ)q−1+C1)ds+LM∫t2τ(t−s)q−1|x(s)−y(s)|ds+|B|Mδ∫τ0(t−s)q−1ds+|B|Mδ∫2ττ(t−s)q−1(K0(s−τ)q−1+C0)ds+|B|Mδ∫t2τ(t−s)q−1(K1(s−2τ)q−1+C1)ds≤δM(2τ)q−1+δLMK0(3τ)2q−1Beta[1/3,q,q]+δLMC0(3τ)qq−+δLMK1(2τ)2q−1Beta[1/2,q,q]+δLMC1(2q)qq+LM∫t2τ(t−s)q−1|x(s)−y(s)|ds+|B|Mδ(3τ)qq+|B|MδK0(2τ)2q−1Beta[1/2,q,q]+|B|MδC0(2τ)qq+δ|B|MK1τqΓ2(q)Γ(2q)(t−2τ)q−1+δ|B|MC1τqq≤δ|B|MK1τqΓ2(q)Γ(2q)(t−2τ)q−1+δP2+LM∫t2τ(t−s)q−1|x(s)−y(s)|ds |
where Beta[x,q,q] is the incomplete beta function.
According to Proposition 3 we obtain
|x(t)−y(t)|≤δ|B|MK1τqΓ2(q)Γ(2q)(t−2τ)q−1+δP2+δP2∫t2τ[∞∑n=1(MLΓ(q))n(t−s)nq−1Γ(nq)]ds+δ|B|MK1τqΓ2(q)Γ(2q)∫t2τ[∞∑n=1(MLΓ(q))n(t−s)nq−1Γ(nq)(s−2τ)q−1]ds≤δP2∞∑n=0(MLΓ(q))n(t−2τ)nqΓ(nq+1)+δ|B|MK1τqΓ3(q)Γ(2q)(t−2τ)q−1∞∑n=0(MLΓ(q))n(t−2τ)nqΓ(q+nq)=δ|B|MK1τqΓ3(q)Γ(2q)Eq,q(MLΓ(q)(t−2τ)q)(t−2τ)q−1+δP2Eq(MLΓ(q)(t−2τ)q)=K2(t−2τ)q−1+C2, t∈(2τ,3τ], |
where K2=δ|B|MK1τqΓ3(q)Γ(2q)Eq,q(MLΓ(q)(t−2τ)q) and C2=δP2Eq(MLΓ(q)(τ)q).
Continue the induction process we prove the claim.
Corollary 1. Let the conditions of Theorem 3 be satisfied and q>0.5.
Then for any positive numbers δ,ε: ε<τ there exists a number K,C>0 such that the inequality ||g−p||[−τ,0]<δ implies
|x(t)−y(t)|≤δK for t∈(ε,T], | (3.18) |
where x(t),y(t) are mild solutions of the IVPs (2.5), (2.2), (2.3) and (2.5), (3.11), (3.12) respectively.
P r o o f: The proof is similar to the one of Theorem 3 applying the inequality (t−kτ)2q−1q≤τqq for t∈(kτ,(k+1)τ], k=0,1,…,N.
In this section we will define and study the finite time stability of mild solutions of the IVP for Riemann-Liouville (2.5), (2.2), (2.3).
Note that because of the singularity of tq−1 at 0, we could prove the FTS on an interval which does not contain 0.
Theorem 4. Let the function g∈C([τ,0],R, |g(0)|<∞, q>0.5 and the condition (A1) be satisfied.
Then for any real positive numbers δ,ε: ε<τ there exists a number K depending on δ and ε such that the inequality ||g||[−τ,0]<δ implies |x(t)|<K for t∈(ε,T] where x(t) is the mild solution of the IVP (2.5), (2.2), (2.3).
P r o o f: Let ||g||[−τ,0]<δ and M=supt∈J|Eq,q(Atq)|.
Let t∈(0,τ]. Then according to Definition 1 we have
|x(t)|≤δEq,q(Atq)tq−1+|B|δ∫t0(t−s)q−1Eq,q(A(t−s)q)|ds +∫t0(t−s)q−1Eq,q(A(t−s)q)|f(s,x(s))|ds≤δMtq−1+|B|Mδ∫t0(t−s)q−1ds+M||w||I∫t0(t−s)q−1ds≤δMtq−1+M(|B|δ+||w||I)τqq, t∈(0,τ]. | (3.19) |
From (3.19) it follows that
|x(t)|≤δMεq−1+M(|B|δ+||w||I)τqq, t∈(ε,τ]. | (3.20) |
Let t∈(τ,2τ]. Then we have
|x(t)|≤δMτq−1+M∫t0(t−s)q−1|f(s,x(s))|ds +|B|Mδ∫τ0(t−s)q−1ds+|B|M∫tτ(t−s)q−1x(s−τ)ds≤δMτq−1+M((||w||I+|B|δ)(2τ)qq+|B|M(δMτ2q−12q−1+M(||w||I+|B|δ)(τqq)2)=K1. |
Let t∈(2τ,3τ]. Then we have
|x(t)|≤δM(2τ)q−1+M∫t0(t−s)q−1|f(s,x(s))|ds+|B|Mδ∫τ0(t−s)q−1ds+|B|M∫2ττ(τ−s)q−1(δM(s−τ)q−1+M(|B|δ+||w||I)τqq)ds+|B|MK1∫t2τ(t−s)q−1ds≤δM(2τ)q−1+|M(|w||I+|B|δ)(3τ)qq+|B|M(δMτ2q−12q−1+M(|B|δ+||w||I)(τqq))2+K1τq)=K2. |
Let t∈(3τ,4τ]. Then we have
|x(t)|≤δM(3τ)q−1+|M(|w||I+|B|δ)(4τ)qq+|B|M(δMτ2q−12q−1+M(|B|δ+||w||I)(τqq)2)+|B|Mτq(K1+K2)=K3. |
Following the induction process we prove the claim with K=δM(Nτ)q−1+|M(|w||I+|B|δ)(Nτ)qq+|B|M(δMτ2q−12q−1+M(|B|δ+||w||I)(τqq)2)+|B|Mτq∑Ni=1Ki.
In the case the nonlinear Lipschitz functions we obtain the following result:
Theorem 5. Let the function g∈C([τ,0],R, |g(0)|<∞, q>0.5 and the condition (A2) be satisfied.
Then for any real positive numbers δ,ε: ε<τ there exists a number K depending on δ and ε such that the inequality ||g||[−τ,0]<δ implies |x(t)|<K for t∈(ε,T] where x(t) is the mild solution of the IVP (2.5), (2.2), (2.3).
P r o o f: According to Theorem 1 the the IVP (2.5), (2.2), (2.3) has a unique solution x∈PC(J,R). Let ||g||[−τ,0]<δ and M=supt∈J|Eq,q(Atq)|.
Let t∈(ε,τ]. Then according to Definition 1 we have
|x(t)|≤δEq,q(Atq)tq−1+|B|δ∫t0(t−s)q−1Eq,q(A(t−s)q)ds +L∫t0(t−s)q−1Eq,q(A(t−s)q)|x(s)|ds≤δMtq−1+|B|Mδτqq+LM∫t0(t−s)q−1|x(s)|ds. | (3.21) |
From (3.21) and Proposition 3 it follows that
|x(t)|≤δMtq−1+|B|Mδτqq+∫t0(∞∑n=1(LMΓ(q))nΓ(nq)(t−s)nq−1(δMsq−1+|B|Mδτqq))ds≤δMtq−1+|B|Mδτqq+δMtq−1Γ(q)∞∑n=1(LMΓ(q))nΓ(nq+q)tnq+|B|Mδτqq∞∑n=1(LMΓ(q))nΓ(nq+1)(t)nq≤δMtq−1+|B|Mδτqq+δMεq−1Γ(q)∞∑n=1(LMΓ(q))nΓ(nq+q)tnq+|B|Mδτqq∞∑n=1(LMΓ(q))nΓ(nq+1)(t)nq≤δMtq−1Γ(q)Eq,q(LMΓ(q))tq)+|B|MδτqqEq(LMΓ(q))tq). | (3.22) |
Therefore,
x(t)≤δ(Mεq−1Γ(q)+|B|Mτqq)Eq(LMΓ(q))τq)=δK0, t∈(ε,τ]. | (3.23) |
Let t∈(τ,2τ]. Then from (3.23) we have
|x(t)|≤δMtq−1+ML∫t0(t−s)q−1|x(s)|ds +|B|Mδ∫τ0(t−s)q−1ds+|B|M∫tτ(t−s)q−1x(s−τ)ds≤δMtq−1+|B|Mδ(1+K0)τqq+ML∫t0(t−s)q−1|x(s)|ds. |
From (3.24) and Proposition 3 it follows that
|x(t)|≤δMtq−1+|B|Mδ(1+K0)τqq+∫tτ(∞∑n=1(MLΓ(q))nΓ(nq)(t−s)nq−1(δMsq−1+|B|Mδ(1+K0)τqq))ds≤δMtq−1Γ(q)Eq,q(LMΓ(q))tq)+|B|Mδ(1+K0)τqq]Eq(LMΓ(q))tq). | (3.24) |
Therefore,
|x(t)|≤δ(Mεq−1Γ(q)+|B|M(1+K0)τqq)Eq(LMΓ(q))τq)=δK1, t∈(τ,2τ] | (3.25) |
Following the induction process we obtain
|x(t)|≤δ(Mεq−1Γ(q)+|B|M(1+Kk−1)τqq)Eq(LMΓ(q))τq)=δKk, t∈(kτ,(k+1)τ], |
where Kk=(Mεq−1Γ(q)+|B|M(1+Kk−1)τqq)Eq(LMΓ(q))τq), k=1,2,…,N.
Example 4. Consider the IVP (3.1) with RL fractional equation RL0D0.5tx(t)=0.1x(t−1)+0.01sin(x(t)). According to Example 3 it has unique mild solution x(t) which is satisfying the integral presentation given in Definition 1. Also, according to Theorem 5 for δ=1, ε=0.001 the inequality |x(t)|<K holds for t∈[0.001,3] where M=sup[0,3]E0.5,0.5(0.1t0.5)=0.7772, K0=(0.7772∗0.0010.5−1Γ(0.5)+0.1∗0.777210.5)Eq(0.11∗0.7772Γ(0.5))=52.321, K1=62.0518 and K=K2=63.8615.
We study scalar nonlinear RL fractional differential equations with constant delays. An appropriate initial value problem for studd equations is set up based on the idea of the initial time interval for delay differential equations with ordinary derivatives. A mild solution is defined based on an appropriate integral representation of the solution. The existence, continuous dependence and finite time stability of the scalar nonlinear RL fractional differential equations is studied by the help of fractional generalization of Gronwall inequality. The obtained integral representations could be successfully applied to study many qualitative investigation of the properties of the solutions of nonlinear RL fractional differential equations.
Research was partially supported by Fund Scientific Research MU19-FMI-009, Plovdiv University.
All authors declare no conflicts of interest in this paper.
[1] | Cavadas LF, Nunes A, Pinheiro M, et al. (2010) Management of menopause in primary health care. Acta Med Port 23: 227-236. |
[2] |
Ceylan B, Özerdoğan N (2015) Factors affecting age of onset of menopause and determination of quality of life in menopause. Turk J Obstet Gynecol 12: 43-49. https://doi.org/10.4274/tjod.79836 ![]() |
[3] |
Nappi RE, Simoncini T (2021) Menopause transition: A golden age to prevent cardiovascular disease. Lancet Diabetes Endocrinol 9: 135-137. https://doi.org/10.1016/S2213-8587(21)00018-8 ![]() |
[4] |
Silva TR, Oppermann K, Reis FM, et al. (2021) Nutrition in menopausal women: A narrative review. Nutrients 13: 2149. https://doi.org/10.3390/nu13072149 ![]() |
[5] |
Di Daniele N, Noce A, Vidiri MF, et al. (2017) Impact of Mediterranean diet on metabolic syndrome, cancer and longevity. Oncotarget 8: 8947-8979. https://doi.org/10.18632/oncotarget.13553 ![]() |
[6] |
Trichopoulou A, Costacou T, Bamia C, et al. (2003) Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med 348: 2599-2608. https://doi.org/10.1056/NEJMoa025039 ![]() |
[7] |
Pes GM, Dore MP, Tsofliou F, et al. (2022) Diet and longevity in the Blue Zones: A set-and-forget issue?. Maturitas 164: 31-37. https://doi.org/10.1016/j.maturitas.2022.06.004 ![]() |
[8] |
Morris L, Bhatnagar D (2016) The Mediterranean diet. Curr Opin Lipidol 27: 89-91. https://doi.org/10.1097/MOL.0000000000000266 ![]() |
[9] |
Barbosa C, Real H, Pimenta P (2017) Roda da alimentação mediterrânica e pirâmide da dieta mediterrânica: comparação entre os dois guias alimentares. Acta Portuguesa de Nutrição 11: 6-14. https://doi.org/10.21011/apn.2017.1102 ![]() |
[10] |
Castro-Quezada I, Román-Viñas B, Serra-Majem L (2014) The mediterranean diet and nutritional adequacy: A review. Nutrients 6: 231-248. https://doi.org/10.3390/nu6010231 ![]() |
[11] |
Page MJ, Moher D, Bossuyt PM, et al. (2021) PRISMA 2020 explanation and elaboration: Updated guidance and exemplars for reporting systematic reviews. BMJ 372: n160. https://doi.org/10.1136/bmj.n160 ![]() |
[12] |
Higgins JP, Savović J, Page MJ, et al. (2019) Assessing risk of bias in a randomized trial. Cochrane handbook for systematic reviews of interventions . Cureus 205-228. https://doi.org/10.1002/9781119536604.ch8 ![]() |
[13] |
Sterne JA, Hernán MA, Reeves BC, et al. (2016) ROBINS-I: A tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355: i4919. https://doi.org/10.1136/bmj.i4919 ![]() |
[14] |
McGuinness LA, Higgins JPT (2021) Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods 12: 55-61. https://doi.org/10.1002/jrsm.1411 ![]() |
[15] |
Rodriguez AS, Soidan JLG, Santos MDT, et al. (2016) Benefits of an educational intervention on diet and anthropometric profile of women with one cardiovascular risk factor. Medicina Clinica 146: 436-439. https://doi.org/10.1016/j.medcle.2016.06.047 ![]() |
[16] |
Lombardo M, Perrone MA, Guseva E, et al. (2020) Losing weight after menopause with minimal aerobic training and mediterranean diet. Nutrients 12: 1-12. https://doi.org/10.3390/nu12082471 ![]() |
[17] |
Vignini A, Nanetti L, Raffaelli F, et al. (2017) Effect of 1-y oral supplementation with vitaminized olive oil on platelets from healthy postmenopausal women. Nutrition 42: 92-98. https://doi.org/10.1016/j.nut.2017.06.013 ![]() |
[18] | Duś-Zuchowska M, Bajerska J, Krzyzanowska P, et al. (2018) The central European diet as an alternative to the mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome-A randomized nutritional trial. Acta Sci Pol Technol Aliment 17: 399-407. https://doi.org/10.17306/J.AFS.0593 |
[19] |
Muzsik A, Bajerska J, Jeleń HH, et al. (2019) FADS1 and FADS2 polymorphism are associated with changes in fatty acid concentrations after calorie-restricted Central European and Mediterranean diets. Menopause 26: 1415-1424. https://doi.org/10.1097/GME.0000000000001409 ![]() |
[20] |
Bajerska J, Chmurzynska A, Muzsik A, et al. (2018) Weight loss and metabolic health effects from energy-restricted mediterranean and Central-European diets in postmenopausal women: A randomized controlled trial. Sci Rep 8: 11170. https://doi.org/10.1038/s41598-018-29495-3 ![]() |
[21] |
Bihuniak JD, Ramos A, Huedo-Medina T, et al. (2016) Adherence to a mediterranean-style diet and its influence on cardiovascular risk factors in postmenopausal women. J Acad Nutr Diet 116: 1767-1775. https://doi.org/10.1016/j.jand.2016.06.377 ![]() |
[22] |
Martínez-González MA, García-Arellano A, Toledo E, et al. (2012) A 14-item mediterranean diet assessment tool and obesity indexes among high-risk subjects: The PREDIMED trial. PLoS One 7: e43134. https://doi.org/10.1371/journal.pone.0043134 ![]() |
[23] |
Panagiotakos DB, Pitsavos C, Stefanadis C (2006) Dietary patterns: A mediterranean diet score and its relation to clinical and biological markers of cardiovascular disease risk. Nutr Metab Cardiovasc Dis 16: 559-568. https://doi.org/10.1016/j.numecd.2005.08.006 ![]() |
[24] |
Ganguly P, Alam SF (2015) Role of homocysteine in the development of cardiovascular disease. Nutr J 14: 1-10. https://doi.org/10.1186/1475-2891-14-6 ![]() |
[25] |
Olén NB, Lehsten V (2022) High-resolution global population projections dataset developed with CMIP6 RCP and SSP scenarios for year 2010–2100. Data Brief 40: 107804. https://doi.org/10.1016/j.dib.2022.107804 ![]() |
[26] |
Silva TRd, Martins CC, Ferreira LL, et al. (2019) Mediterranean diet is associated with bone mineral density and muscle mass in postmenopausal women. Climacteric 22: 162-168. https://doi.org/10.1080/13697137.2018.1529747 ![]() |
[27] |
Al-Safi ZA, Polotsky AJ (2015) Obesity and menopause. Best Pract Res Clin Obstet Gynaecol 29: 548-553. https://doi.org/10.1016/j.bpobgyn.2014.12.002 ![]() |
[28] |
Greendale GA, Sternfeld B, Huang M, et al. (2019) Changes in body composition and weight during the menopause transition. JCI Insight 4: e124865. https://doi.org/10.1172/jci.insight.124865 ![]() |
[29] | Maltais ML, Desroches J, Dionne IJ (2009) Changes in muscle mass and strength after menopause. J Musculoskelet Neuronal Interact 9: 186-197. |
[30] |
Aloia JF, McGowan DM, Vaswani AN, et al. (1991) Relationship of menopause to skeletal and muscle mass. Am J Clin Nutr 53: 1378-1383. https://doi.org/10.1093/ajcn/53.6.1378 ![]() |
[31] |
Forsmo S, Hvam HM, Rea ML, et al. (2007) Height loss, forearm bone density and bone loss in menopausal women: a 15-year prospective study. The Nord-Trøndelag Health Study, Norway. Osteoporos Int 18: 1261-1269. https://doi.org/10.1007/s00198-007-0369-1 ![]() |
[32] |
Mancini JG, Filion KB, Atallah R, et al. (2016) Systematic review of the Mediterranean diet for long-term weight loss. Am J Med 129: 407-415. https://doi.org/10.1016/j.amjmed.2015.11.028 ![]() |
[33] |
Kim JY (2021) Optimal diet strategies for weight loss and weight loss maintenance. J Obes Metab Syndr 30: 20-31. https://doi.org/10.7570/jomes20065 ![]() |
[34] |
Muscogiuri G, Verde L, Sulu C, et al. (2022) Mediterranean diet and obesity-related disorders: what is the evidence?. Curr Obes Rep 11: 287-304. https://doi.org/10.1007/s13679-022-00481-1 ![]() |
[35] |
Dinu M, Pagliai G, Casini A, et al. (2018) Mediterranean diet and multiple health outcomes: An umbrella review of meta-analyses of observational studies and randomised trials. Eur J Clin Nutr 72: 30-43. https://doi.org/10.1038/ejcn.2017.58 ![]() |
[36] |
Buckinx F, Aubertin-Leheudre M (2022) Sarcopenia in menopausal women: Current perspectives. Int J Womens Health 14: 805-819. https://doi.org/10.2147/IJWH.S340537 ![]() |
[37] |
Finkelstein JS, Brockwell SE, Mehta V, et al. (2008) Bone mineral density changes during the menopause transition in a multiethnic cohort of women. J Clin Endocrinol Metab 93: 861-868. https://doi.org/10.1210/jc.2007-1876 ![]() |
[38] |
Papadopoulou SK, Detopoulou P, Voulgaridou G, et al. (2023) Mediterranean diet and sarcopenia features in apparently healthy adults over 65 years: A systematic review. Nutrients 15: 1104. https://doi.org/10.3390/nu15051104 ![]() |
[39] | Antunes S, Marcelino O, Aguiar T (2003) Fisiopatologia da menopausa. Revista Portuguesa de Medicina Geral e Familiar 19: 353-357. |
[40] |
Taddei S (2009) Blood pressure through aging and menopause. Climacteric 12: 36-40. https://doi.org/10.1080/13697130903004758 ![]() |
[41] |
Widmer RJ, Flammer AJ, Lerman LO, et al. (2015) The Mediterranean diet, its components, and cardiovascular disease. Am J Med 128: 229-238. https://doi.org/10.1016/j.amjmed.2014.10.014 ![]() |
[42] |
Tuttolomondo A, Simonetta I, Daidone M, et al. (2019) Metabolic and vascular effect of the mediterranean diet. Int J Mol Sci 20: 4716. https://doi.org/10.3390/ijms20194716 ![]() |
[43] |
Rizza S, Tesauro M, Cardillo C, et al. (2009) Fish oil supplementation improves endothelial function in normoglycemic offspring of patients with type 2 diabetes. Atherosclerosis 206: 569-574. https://doi.org/10.1016/j.atherosclerosis.2009.03.006 ![]() |
[44] |
Paar M, Pavenstädt H, Kusche-Vihrog K, et al. (2014) Endothelial sodium channels trigger endothelial salt sensitivity with aging. Hypertension 64: 391-396. https://doi.org/10.1161/HYPERTENSIONAHA.114.03348 ![]() |
[45] |
Viroli G, Gonçalves C, Pinho O, et al. (2021) High adherence to Mediterranean diet is not associated with an improved sodium and potassium intake. Nutrients 13: 4151. https://doi.org/10.3390/nu13114151 ![]() |
[46] |
Goncalves C, Abreu S (2020) Sodium and potassium intake and cardiovascular disease in older people: A systematic review. Nutrients 12: 3447. https://doi.org/10.3390/nu12113447 ![]() |
[47] |
Esposito K, Maiorino MI, Bellastella G, et al. (2015) A journey into a Mediterranean diet and type 2 diabetes: A systematic review with meta-analyses. BMJ Open 5: e008222. https://doi.org/10.1136/bmjopen-2015-008222 ![]() |
[48] |
Sofi F, Cesari F, Abbate R, et al. (2008) Adherence to Mediterranean diet and health status: Meta-analysis. BMJ 337: a1344. https://doi.org/10.1136/bmj.a1344 ![]() |
![]() |
![]() |
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