Overview and current status of published research on cancer, sarcopenia and physical activity: A bibliometric analysis

J. A. Parraca; D. Salas-Gómez; R. Dinis; A. Denche-Zamorano; A. Vega-Muñoz; P. Tomas-Carus; J. A. Parraca; D. Salas-Gómez; R. Dinis; A. Denche-Zamorano; A. Vega-Muñoz; P. Tomas-Carus

doi:10.3934/publichealth.2025033

AIMS Public Health

2025, Volume 12, Issue 3: 632-656. doi: 10.3934/publichealth.2025033

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Review

Overview and current status of published research on cancer, sarcopenia and physical activity: A bibliometric analysis

1.
Departamento de Desporto e Saúde, Escola de Saúde e Desenvolvimento Humano, Universidade de Évora, 7004-516 Evora, Portugal
2.
Comprehensive Health Research Centre (CHRC), University of Evora, 7004-516 Evora, Portugal
3.
Medical Oncology, Hospital do Espirito Santo de Evora EPE, Evora, Portugal
4.
Promoting a Healthy Society Research Group (PHeSO), Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain
5.
Centro de Investigación en Educación de Calidad para la Equidad, Universidad Central de Chile, Santiago 8330601, Chile
6.
Facultad de Ciencias Empresariales, Universidad Arturo Prat, Iquique 1110939, Chile

Received: 05 February 2025 Revised: 28 March 2025 Accepted: 24 April 2025 Published: 23 June 2025

Introduction
Cancer is a global health problem; the presence of secondary symptoms such as sarcopenia in cancer patients is relatively common. Physical activity (PA) is notable for its protective role against sarcopenia; however, there is currently no bibliometric analysis of research related to cancer, sarcopenia, and physical activity.
Methods
A search on the Web of Science (WoS) Core Collection database was performed on this topic, and a bibliometric analysis of the identified publications was performed using traditional bibliometric laws.
Results
121 publications were found. Annual publications presented an exponentially growing trend from 2012 to 2023 (R² = 91%). The United States of America was the country with the most documents worldwide. Newton, R. U. and Galvao, D. A. were highlighted as the most prolific and prominent co-authors. The Cancers and Journal of Cachexia, Sarcopenia and Muscle were the journals with the highest number of published documents. 36 papers, having 37 or more citations, were the most cited papers. The author keywords and keywords Plus® identified thematic clusters related to research on this topic, such as cancer, physical activity, aging, muscle, skeletal muscle, osteoporosis, malnutrition, body composition, cachexia, survival, and frailty.
Conclusion
Research on cancer, sarcopenia, and physical activity has followed an exponential growth trend, which reveals growing interest in the topic. Significant authors and collaborative groups in the field were identified, as well as the journals and countries with the highest number of publications and the research trends most followed by researchers.
- physical inactivity,
- review,
- neoplasia,
- physical function,
- loss mass,
- quality of life
Citation: J. A. Parraca, D. Salas-Gómez, R. Dinis, A. Denche-Zamorano, A. Vega-Muñoz, P. Tomas-Carus. Overview and current status of published research on cancer, sarcopenia and physical activity: A bibliometric analysis[J]. AIMS Public Health, 2025, 12(3): 632-656. doi: 10.3934/publichealth.2025033

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Abstract

Introduction

Cancer is a global health problem; the presence of secondary symptoms such as sarcopenia in cancer patients is relatively common. Physical activity (PA) is notable for its protective role against sarcopenia; however, there is currently no bibliometric analysis of research related to cancer, sarcopenia, and physical activity.

Methods

A search on the Web of Science (WoS) Core Collection database was performed on this topic, and a bibliometric analysis of the identified publications was performed using traditional bibliometric laws.

Results

121 publications were found. Annual publications presented an exponentially growing trend from 2012 to 2023 (R² = 91%). The United States of America was the country with the most documents worldwide. Newton, R. U. and Galvao, D. A. were highlighted as the most prolific and prominent co-authors. The Cancers and Journal of Cachexia, Sarcopenia and Muscle were the journals with the highest number of published documents. 36 papers, having 37 or more citations, were the most cited papers. The author keywords and keywords Plus® identified thematic clusters related to research on this topic, such as cancer, physical activity, aging, muscle, skeletal muscle, osteoporosis, malnutrition, body composition, cachexia, survival, and frailty.

Conclusion

Research on cancer, sarcopenia, and physical activity has followed an exponential growth trend, which reveals growing interest in the topic. Significant authors and collaborative groups in the field were identified, as well as the journals and countries with the highest number of publications and the research trends most followed by researchers.

Acknowledgments

The author A.D.-Z. (FPU20/04201) was supported by a grant from the Spanish Ministry of Education, Culture, and Sport. Grants FPU20/04201 funded by MCIN/AEI/10.13039/501100011033 and, as appropriate, by “European Social Found Investing in your future” or by “European Union NextGenerationEU/PRTR”.
This study has been partially supported by national funds through the Foundation for Science and Technology, un-der the project UIDP/04923/2020.

Authors' contributions

Conceptualization, J.A.P. and P.T.-C.; Methodology, A.V.-M., A.D.-Z. and D.S.-G.; Software, D.S.-G. and A.D.-Z.; Formal Analysis, A.D.-Z. and D.S.-G.; Writing – Original Draft Preparation, A.D.-Z. and D.S.-G.; Writing – Review & Editing, A.D.-Z. and D.S.-G.; Visualization, R.D., A.V.-M., J.A.P. and P.T.-C.; Supervision, R.D., A.V.-M., J.A.P. and P.T.-C.; Funding Acquisition, J.A.P. and P.T.-C.

Conflict of interest

The authors declare that they have no conflicts of interest.

References

[1]	Zheng R, Wang S, Zhang S, et al. (2023) Global, regional, and national lifetime probabilities of developing cancer in 2020. Sci Bull (Beijing) 68: 2620-2628. https://doi.org/10.1016/j.scib.2023.09.041
[2]	WHOGlobal cancer burden growing, amidst mounting need for services (2024). [cited 2024 September 19]. Available from: https://www.who.int/news/item/01-02-2024-global-cancer-burden-growing--amidst-mounting-need-for-services
[3]	Mattiuzzi C, Lippi G (2019) Current cancer epidemiology. J Epidemiol Glob Health 9: 217-222. https://doi.org/10.2991/jegh.k.191008.001
[4]	Newsham Izzy, Sendera Marcin, Jammula Sri Ganesh, et al. (2024) Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns. Biol Methods Protoc 9: bpae028. https://doi.org/10.1093/biomethods/bpae028
[5]	Milner DA, Lennerz JK (2024) Technology and future of multi-cancer early detection. Life (Basel) 14: 833. https://doi.org/10.3390/life14070833
[6]	Miller KD, Siegel RL, Lin CC, et al. (2016) Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin 66: 271-289. https://doi.org/10.3322/caac.21349
[7]	Campbell KL, Winters-Stone K, Wiskemann J, et al. (2019) Exercise guidelines for cancer survivors: Consensus statement from international multidisciplinary roundtable. Med Sci Sports Exerc 51: 2375-2390. https://doi.org/10.1249/MSS.0000000000002116
[8]	Nayak MG, George A, Vidyasagar MS, et al. (2017) Quality of life among cancer patients. Indian J Palliat Care 23: 445-450. https://doi.org/10.4103/IJPC.IJPC_82_17
[9]	Gegechkori N, Haines L, Lin JJ (2017) Long term and latent side effects of specific cancer types. Med Clin North Am 101: 1053-1073. https://doi.org/10.1016/j.mcna.2017.06.003
[10]	Stein KD, Syrjala KL, Andrykowski MA (2008) Physical and psychological long-term and late effects of cancer. Cancer 112: 2577-2592. https://doi.org/10.1002/cncr.23448
[11]	Liu T, Song F, Su D, et al. (2023) Bibliometric analysis of research trends in relationship between sarcopenia and surgery. Front Surg 9: 1056732. https://doi.org/10.3389/fsurg.2022.1056732
[12]	Gangadharan A, Choi SE, Hassan A, et al. (2017) Protein calorie malnutrition, nutritional intervention and personalized cancer care. Oncotarget 8: 24009-24030. https://doi.org/10.18632/oncotarget.15103
[13]	Anjanappa M, Corden M, Green A, et al. (2020) Sarcopenia in cancer: Risking more than muscle loss. Tech Innov Patient Support Radiat Oncol 16: 50-57. https://doi.org/10.1016/j.tipsro.2020.10.001
[14]	Miller KD, Nogueira L, Devasia T, et al. (2022) Cancer treatment and survivorship statistics, 2022. CA Cancer J Clin 72: 409-436. https://doi.org/10.3322/caac.21731
[15]	Vance V, Mourtzakis M, McCargar L, et al. (2011) Weight gain in breast cancer survivors: Prevalence, pattern and health consequences. Obes Rev 12: 282-294. https://doi.org/10.1111/j.1467-789X.2010.00805.x
[16]	Gandhi A, Copson E, Eccles D, et al. (2019) Predictors of weight gain in a cohort of premenopausal early breast cancer patients receiving chemotherapy. Breast 45: 1-6. https://doi.org/10.1016/j.breast.2019.02.006
[17]	van den Berg MMGA, Winkels RM, de Kruif JTCM, et al. (2017) Weight change during chemotherapy in breast cancer patients: A meta-analysis. BMC Cancer 17: 259. https://doi.org/10.1186/s12885-017-3242-4
[18]	Cruz-Jentoft AJ, Bahat G, Bauer J, et al. (2019) Sarcopenia: Revised European consensus on definition and diagnosis. Age Ageing 48: 16-31. https://doi.org/10.1093/ageing/afy169
[19]	Bilski J, Pierzchalski P, Szczepanik M, et al. (2022) Multifactorial mechanism of sarcopenia and sarcopenic obesity. Role of physical exercise, microbiota and myokines. Cells 11: 160. https://doi.org/10.3390/cells11010160
[20]	Mir O, Coriat R, Blanchet B, et al. (2012) Sarcopenia predicts early dose-limiting toxicities and pharmacokinetics of sorafenib in patients with hepatocellular carcinoma. PloS One 7: e37563. https://doi.org/10.1371/journal.pone.0037563
[21]	Roberto M, Barchiesi G, Resuli B, et al. (2024) Sarcopenia in breast cancer patients: A systematic review and meta-analysis. Cancers 16: 596. https://doi.org/10.3390/cancers16030596
[22]	Zhang XM, Dou QL, Zeng Y, et al. (2020) Sarcopenia as a predictor of mortality in women with breast cancer: A meta-analysis and systematic review. BMC Cancer 20: 172. https://doi.org/10.1186/s12885-020-6645-6
[23]	Collins J, Noble S, Chester J, et al. (2014) The assessment and impact of sarcopenia in lung cancer: A systematic literature review. BMJ Open 4: e003697. https://doi.org/10.1136/bmjopen-2013-003697
[24]	Lin TY, Chen YF, Wu WT, et al. (2022) Impact of sarcopenia on the prognosis and treatment of lung cancer: An umbrella review. Discov Oncol 13: 115. https://doi.org/10.1007/s12672-022-00576-0
[25]	Luo L, Shen X, Fang S, et al. (2023) Sarcopenia as a risk factor of progression-free survival in patients with metastases: A systematic review and meta-analysis. BMC Cancer 23: 127. https://doi.org/10.1186/s12885-023-10582-2
[26]	Introducción.In directrices de la OMS sobre actividad física y comportamientos sedentarios. World Health Organization (2021) . [cited 2024 September 19]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK581968/
[27]	Islami F, Goding Sauer A, Miller KD, et al. (2018) Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA Cancer J Clin 68: 31-54. https://doi.org/10.3322/caac.21440
[28]	Marino P, Mininni M, Deiana G, et al. (2024) Healthy lifestyle and cancer risk: Modifiable risk factors to prevent cancer. Nutrients 16: 800. https://doi.org/10.3390/nu16060800
[29]	El Assar M, Álvarez-Bustos A, Sosa P, et al. (2022) Effect of physical activity/Exercise on oxidative stress and inflammation in muscle and vascular aging. Int J Mol Sci 23: 8713. https://doi.org/10.3390/ijms23158713
[30]	Schmitz KH, Courneya KS, Matthews C, et al. (2010) American college of sports medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc 42: 1409-1426. https://doi.org/10.1249/MSS.0b013e3181e0c112
[31]	Mohammed Marwa, Li Jianan (2023) Knowledge mapping and visualization of current sarcopenia and cancer research: A bibliometric analysis. CoLab . [cited 2024 September 19]. Available from: https://colab.ws/articles/10.1186%2Fs43088-023-00386-5
[32]	Fu Y, Mao Y, Jiang S, et al. (2023) A bibliometric analysis of systematic reviews and meta-analyses in ophthalmology. Front Med (Lausanne) 10: 1135592. https://doi.org/10.3389/fmed.2023.1135592
[33]	Clarivate (n.d.). Clarivate web of science. [cited 2024 September 16]. Available from: https://access.clarivate.com/login?app=wos&alternative=true&shibShireURL=https:%2F%2Fwww.webofknowledge.com%2F%3Fauth%3DShibboleth&shibReturnURL=https:%2F%2Fwww.webofknowledge.com%2F&roaming=true
[34]	Dobrov GM, Randolph RH, Rauch WD (1979) New options for team research via international computer networks. Scientometrics 1: 387-404. https://doi.org/10.1007/BF02016658
[35]	Price DDS (1976) A general theory of bibliometric and other cumulative advantage processes. J Am Soc Inf Sci 27: 292-306. https://doi.org/10.1002/asi.4630270505
[36]	Laccourreye O, Maisonneuve H (2019) French scientific medical journals confronted by developments in medical writing and the transformation of the medical press. Eur Ann Otorhinolaryngol Head Neck Dis 136: 475-480. https://doi.org/10.1016/j.anorl.2019.09.002
[37]	Contreras-Barraza N, Madrid-Casaca H, Salazar-Sepúlveda G, et al. (2021) Bibliometric analysis of studies on coffee/Caffeine and sport. Nutrients 13: 9. https://doi.org/10.3390/nu13093234
[38]	Crespo N, Simoes N (2019) Publication performance through the lens of the h-index: How can we solve the problem of the ties?. Soc Sci Quart 100: 2495-2506. https://doi.org/10.1111/ssqu.12696
[39]	Hirsch JE (2005) An index to quantify an individual's scientific research output. Proc Natl Acad Sci U S A 102: 16569-16572. https://doi.org/10.1073/pnas.0507655102
[40]	Bulick S (1978) Book use as a Bradford-Zipf phenomenon. Coll Res Libr 39: 3. https://doi.org/10.5860/crl_39_03_215
[41]	Morse PM, Leimkuhler FF (1979) Exact solution for the bradford distribution and its use in modeling informational data. Oper Res 27: 187-198.
[42]	Muñoz-Urtubia N, Vega-Muñoz A, Estrada-Muñoz C, et al. (2024) Wearable biosensors for human health: A bibliometric analysis from 2007 to 2022. Digit Health 10: 20552076241256876. https://doi.org/10.1177/20552076241256876
[43]	Lotka AJ (1926) The frequency distribution of scientific productivity. J Washington Acad Sci 16: 317-323.
[44]	Koo M (2017) A bibliometric analysis of two decades of aromatherapy research. BMC Res Notes 10: 46. https://doi.org/10.1186/s13104-016-2371-1
[45]	Kushairi N, Ahmi A (2021) Flipped classroom in the second decade of the Millenia: A Bibliometrics analysis with Lotka's law. Educ Inf Technol (Dordr) 26: 4401-4431. https://doi.org/10.1007/s10639-021-10457-8
[46]	Denche-Zamorano A, Rodriguez-Redondo Y, Barrios-Fernandez S, et al. (2023) Rehabilitation is the main topic in virtual and augmented reality and physical activity research: A bibliometric analysis. Sensors 23: 6. https://doi.org/10.3390/s23062987
[47]	Pereira-Payo D, Denche-Zamorano Á, Mendoza-Muñoz M, et al. (2024) Trends in multicomponent training research in the aged population: A bibliometric analysis. Healthcare 12: 15. https://doi.org/10.3390/healthcare12151493
[48]	Sainaghi R, Phillips P, Baggio R, et al. (2018) Cross-citation and authorship analysis of hotel performance studies. Int J Hosp Manag 73: 75-84. https://doi.org/10.1016/j.ijhm.2018.02.004
[49]	Amado-Fuentes M, Denche-Zamorano A, Barrios-Fernandez S, et al. (2024) Bibliometric analysis on equine-assisted interventions. Animals 14: 12. https://doi.org/10.3390/ani14121776
[50]	van Eck NJ, Waltman L (2010) Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics 84: 523-538. https://doi.org/10.1007/s11192-009-0146-3
[51]	Zipf GK (1932) Selected studies of the principle of relative frequency in language. Cambridge: Harvard University Press. [cited 2024 September 25]. Available from: https://www.mpi.nl/publications/item2407800/selected-studies-principle-relative-frequency-language.
[52]	Valderrama-Zurián JC, García-Zorita C, Marugán-Lázaro S, et al. (2021) Comparison of MeSH terms and KeyWords Plus terms for more accurate classification in medical research fields. A case study in cannabis research. Inform Process Manag 58: 102658. https://doi.org/10.1016/j.ipm.2021.102658
[53]	Booth FW, Roberts CK, Laye MJ (2012) Lack of exercise is a major cause of chronic diseases. Compr Physiol 2: 1143-1211. https://doi.org/10.1002/cphy.c110025
[54]	Coile RC (1977) Lotka's frequency distribution of scientific productivity. J Am Soc Inf Sci 28: 366-370. https://doi.org/10.1002/asi.4630280610
[55]	Vittori A, Cascella M, Leonardi M, et al. (2022) VOSviewer-Based Bibliometric Network Analysis for Evaluating Research on Juvenile Primary Fibromyalgia Syndrome (JPFS). Children (Basel) 9: 637. https://doi.org/10.3390/children9050637
[56]	Vega-Muñoz A, Salazar-Sepúlveda G, Contreras-Barraza N, et al. (2022) Scientific mapping of coastal governance: Global benchmarks and trends. J Mar Sci Eng 10: 751. https://doi.org/10.3390/jmse10060751
[57]	Curl WW (2000) Aging and exercise: Are they compatible in women?. Clin Orthop Relat Res 372: 151-158. https://doi.org/10.1097/00003086-200003000-00017
[58]	Hansen RD, Raja C, Allen BJ (2000) Total body protein in chronic diseases and in aging. Ann N Y Acad Sci 904: 345-352. https://doi.org/10.1111/j.1749-6632.2000.tb06480.x
[59]	Demark-Wahnefried W, Peterson BL, Winer EP, et al. (2001) Changes in weight, body composition, and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol 19: 2381-2389. https://doi.org/10.1200/JCO.2001.19.9.2381
[60]	Fresno-Alba S, Denche-Zamorano Á, Pastor-Cisneros R, et al. (2023) Breast cancer and physical activity: A bibliometric analysis. Front Oncol 12: 1051482. https://doi.org/10.3389/fonc.2022.1051482
[61]	Dunne RF, Williams GR, et al. (2019) Cachexia and sarcopenia in older adults with cancer: A comprehensive review. Cancers 11: 1861. https://doi.org/10.3390/cancers11121861
[62]	Cao A, Ferrucci LM, Caan BJ, et al. (2022) Effect of exercise on sarcopenia among cancer survivors: A systematic review. Cancers (Basel) 14: 786. https://doi.org/10.3390/cancers14030786
[63]	Adams SC, Segal RJ, McKenzie DC, et al. (2016) Impact of resistance and aerobic exercise on sarcopenia and dynapenia in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial. Breast Cancer Res Tr 158: 497-507. https://doi.org/10.1007/s10549-016-3900-2
[64]	Yamamoto K, Nagatsuma Y, Fukuda Y, et al. (2017) Effectiveness of a preoperative exercise and nutritional support program for elderly sarcopenic patients with gastric cancer. Gastric Cancer 20: 913-918. https://doi.org/10.1007/s10120-016-0683-4
[65]	Dawson JK, Dorff TB, Todd Schroeder E, et al. (2018) Impact of resistance training on body composition and metabolic syndrome variables during androgen deprivation therapy for prostate cancer: A pilot randomized controlled trial. BMC Cancer 18: 368. https://doi.org/10.1186/s12885-018-4306-9
[66]	Dieli-Conwright CM, Courneya KS, Demark-Wahnefried W, et al. (2018) Effects of aerobic and resistance exercise on metabolic syndrome, sarcopenic obesity, and circulating biomarkers in overweight or obese survivors of breast cancer: A randomized controlled trial. J Clin Oncol 36: 875-883. https://doi.org/10.1200/JCO.2017.75.7526
[67]	Koya S, Kawaguchi T, Hashida R, et al. (2019) Effects of in-hospital exercise on sarcopenia in hepatoma patients who underwent transcatheter arterial chemoembolization. J Gastroenterol Hepatol 34: 580-588. https://doi.org/10.1111/jgh.14538
[68]	Moug SJ, Barry SJE, Maguire S, et al. (2020) Does prehabilitation modify muscle mass in patients with rectal cancer undergoing neoadjuvant therapy? A subanalysis from the REx randomised controlled trial. Tech Coloproctol 24: 959-964. https://doi.org/10.1007/s10151-020-02262-1
[69]	Delrieu L, Martin A, Touillaud M, et al. (2021) Sarcopenia and serum biomarkers of oxidative stress after a 6-month physical activity intervention in women with metastatic breast cancer: Results from the ABLE feasibility trial. Breast Cancer Res Treat 188: 601-613. https://doi.org/10.1007/s10549-021-06238-z
[70]	Bauer J, Morley JE, Schols AMWJ, et al. (2019) Sarcopenia: A time for action. An SCWD position paper. J Cachexia Sarcopenia Muscle 10: 956-961. https://doi.org/10.1002/jcsm.12483
[71]	Correa-de-Araujo R, Addison O, Miljkovic I, et al. (2020) Myosteatosis in the context of skeletal muscle function deficit: An interdisciplinary workshop at the national institute on aging. Front Physiol 11: 963. https://doi.org/10.3389/fphys.2020.00963
[72]	Romanello V, Sandri M (2015) Mitochondrial quality control and muscle mass maintenance. Front Physiol 6: 422. https://doi.org/10.3389/fphys.2015.00422
[73]	Trovato E, Di Felice V, Barone R (2019) Extracellular vesicles: Delivery vehicles of myokines. Front Physiol 10: 522. https://doi.org/10.3389/fphys.2019.00522
[74]	Zinna EM, Yarasheski KE (2003) Exercise treatment to counteract protein wasting of chronic diseases. Curr Opin Clin Nutr Metab Care 6: 87-93. https://doi.org/10.1097/00075197-200301000-00013
[75]	Di Girolamo FG, Situlin R, Mazzucco S, et al. (2014) Omega-3 fatty acids and protein metabolism: Enhancement of anabolic interventions for sarcopenia. Curr Opin Clin Nutr Metab Care 17: 145-150. https://doi.org/10.1097/MCO.0000000000000032
[76]	Marzetti Emanuele, Calvani Riccardo, Tosato Matteo, et al. (2017) Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging-Clin Exp Res 29: 35-42. https://doi.org/10.1007/s40520-016-0705-4
[77]	Galvão DA, Spry NA, Taaffe DR, et al. (2008) Changes in muscle, fat and bone mass after 36 weeks of maximal androgen blockade for prostate cancer. BJU Int 102: 44-47. https://doi.org/10.1111/j.1464-410X.2008.07539.x
[78]	Newton RU, Galvão DA (2008) Exercise in prevention and management of cancer. Curr Treat Options Oncol 9: 135-146. https://doi.org/10.1007/s11864-008-0065-1
[79]	Williams GR, Dunne RF, Giri S, et al. (2021) Sarcopenia in the older adult with cancer. J Clin Oncol 39: 2068-2078. https://doi.org/10.1200/JCO.21.00102
[80]	Valentino NP, Gomes TLN, Barreto CS, et al. (2021) Low phase angle is associated with the risk for sarcopenia in unselected patients with cancer: Effects of hydration. Nutrition 84: 111122. https://doi.org/10.1016/j.nut.2020.111122
[81]	Melzer K, Kayser B, Pichard C (2004) Physical activity: The health benefits outweigh the risks. Curr Opin Clin Nutr Metab Care 7: 641-647. https://doi.org/10.1097/00075197-200411000-00009
[82]	Wu J, Chi H, Kok S, et al. (2024) Multimodal prerehabilitation for elderly patients with sarcopenia in colorectal surgery. Ann Coloproctol 40: 3-12. https://doi.org/10.3393/ac.2022.01207.0172

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