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Incommensurate fractional epidemic dynamics with compartment-specific memory, treatment response, and physics-informed forecasting

  • Published: 27 July 2026
  • MSC : 92D30, 34A08, 34D20, 65L05

  • This paper develops an incommensurate fractional-order susceptible-exposed-symptomatic infectious-asymptomatic infectious-treated-recovered (SEIATR) model with compartment-specific Caputo memory. We establish local well-posedness, positivity, boundedness, biological feasibility, disease-free and endemic equilibria, and the basic reproduction number. Local stability is analyzed through the rational-order incommensurate Matignon criterion. A componentwise multi-order L1 scheme is then used for simulation, refinement, and sensitivity analysis. Finally, a physics-informed neural network is employed as a synthetic benchmark for hidden-state reconstruction, parameter and order identification, residual checking, and short-horizon forecasting. The results show that compartment-specific memory mainly affects peak timing, persistence, and treatment load, whereas epidemiological rates govern amplification and threshold behavior.

    Citation: Zied Elleuch, Younes Brahim Oumedjber, Omar Kahouli, Adel Ouannas, Sulaiman Almohaimeed, Lilia El Amraoui, Mohamed Ayari. Incommensurate fractional epidemic dynamics with compartment-specific memory, treatment response, and physics-informed forecasting[J]. AIMS Mathematics, 2026, 11(7): 22316-22353. doi: 10.3934/math.2026903

    Related Papers:

  • This paper develops an incommensurate fractional-order susceptible-exposed-symptomatic infectious-asymptomatic infectious-treated-recovered (SEIATR) model with compartment-specific Caputo memory. We establish local well-posedness, positivity, boundedness, biological feasibility, disease-free and endemic equilibria, and the basic reproduction number. Local stability is analyzed through the rational-order incommensurate Matignon criterion. A componentwise multi-order L1 scheme is then used for simulation, refinement, and sensitivity analysis. Finally, a physics-informed neural network is employed as a synthetic benchmark for hidden-state reconstruction, parameter and order identification, residual checking, and short-horizon forecasting. The results show that compartment-specific memory mainly affects peak timing, persistence, and treatment load, whereas epidemiological rates govern amplification and threshold behavior.



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