Implied Maximum Dose Analysis of Standard Values of 25 Pesticides Based on Major Human Exposure Pathways

Zijian Li; Aaron A. Jennings

doi:10.3934/publichealth.2017.4.383

AIMS Public Health , 2017, 4(4): 383-398. doi: 10.3934/publichealth.2017.4.383. Research article

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Implied Maximum Dose Analysis of Standard Values of 25 Pesticides Based on Major Human Exposure Pathways

Zijian Li, Aaron A. Jennings

1 Department of Civil Engineering, Case Western Reserve University, Cleveland, OH 44106, USA
2 Present Address: Parsons Corporation, Chicago, IL 60606, USA

Received: , Accepted: , Published:

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Worldwide jurisdictions are making efforts to regulate pesticide standard values in residential soil, drinking water, air, and agricultural commodity to lower the risk of pesticide impacts on human health. Because human may exposure to pesticides from many ways, such as ingestion, inhalation, and dermal contact, it is important to examine pesticide standards by considering all major exposure pathways. Analysis of implied maximum dose limits for commonly historical and current used pesticides was adopted in this study to examine whether worldwide pesticide standard values are enough to prevent human health impact or not. Studies show that only U.S. has regulated pesticides standard in the air. Only 4% of the total number of implied maximum dose limits is based on three major exposures. For Chlorpyrifos, at least 77.5% of the total implied maximum dose limits are above the acceptable daily intake. It also shows that most jurisdictions haven’t provided pesticide standards in all major exposures yet, and some of the standards are not good enough to protect human health.

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Keywords: pesticide standard; implied maximum dose limits; human health risk; acceptable daily intake; human exposure

Citation: Zijian Li, Aaron A. Jennings. Implied Maximum Dose Analysis of Standard Values of 25 Pesticides Based on Major Human Exposure Pathways. AIMS Public Health , 2017, 4(4): 383-398. doi: 10.3934/publichealth.2017.4.383

References:

1. European Commission. Plants – Pesticide. 2016. Available from: http://ec.europa.eu/food/plant/pesticides/index_en.htm (Accessed on 07.30.2016).
2. U.S. Environmental Protection Agency. U.S. EPA about pesticide. 2014. Available from: http://www.epa.gov/pesticides/about/index.htm (accessed on 03.17.15).
3. University of Minnesota. Pesticides in the Environment-Pesticide Transport and Fate. 2003. Available from: http://enhs.umn.edu/current/5103/pesticide/fate.html (accessed on 01.13.16).
4. Farmworker J (2008) Reproductive Health Effects of Pesticide Exposure. Available from: https://www.farmworkerjustice.org/sites/default/files/documents/Reproductibe%20Health%20Effects%20of%20Pesticide%20Exposure%20-%20Paper.pdf (accessed on 03.25.15).
5. Alewu B, Nosiri C (2011) Pesticides and human health. In: Stoytcheva M, editor. , editor. Pesticides in the Modern World – Effects of Pesticides Exposure. InTech. 231-250. Available from: http://www.intechopen.com/books/pesticides-in-the-modern-world-effects-of-pesticides-exposure/pesticide-and-human-health.
6. Proctor DM, Shay EC, Scott PK (1997) Health-based soil action levels for trivalent and hexavalent chromium: a comparison with state and federal standards. J Soil Contam 6: 595-648.
7. Davis A, Sherwin D, Ditmars R, et al. (2001) An analysis of soil arsenic records of decision. Environ Sci Technol 35: 2401-2406.
8. Jennings A, Li Z (2014) Scope of the worldwide effort to regulate pesticide contamination in surface soils. J Environ Manag 146: 420-443.
9. Li Z, Jennings A (2017) Ranking system for national regulatory jurisdictions based on pesticide standard values in major exposures. AIMS Environ Sci 4: 540-561.
10. Jennings A, Li Z (2017) Worldwide regulatory guidance values applied to direct contact surface soil pesticide contamination: Part II-Noncarcinogenic pesticides. Air Soil Water Res 10: 1-14.
11. Jennings A, Li Z (2017) Worldwide regulatory guidance values applied to direct contact surface soil pesticide contamination: Part I-Carcinogenic pesticides. Air Soil Water Res 10: 1-12.
12. Joon CC, Han RL, Alan DZ, et al. (2016) Fluoride: A naturally-occurring health hazard in drinking-water resources of Northern Thailand. Sci Total Environ 545-546: 266-279.
13. Rachel Baum, Urooj Amjad, Jeanne Luh, et al. (2015) An examination of the potential added value of water safety plans to the United States national drinking water legislation. Int J Hyg Environ Health 218: 677-685.
14. Stockholm Convention. The 12 initial POPs under the Stockholm Convention. 2008. Available from: http://chm.pops.int/TheConvention/ThePOPs/The12InitialPOPs/tabid/296/Default.aspx (accessed on 7/30/2016).
15. Jennings A, Li Z (2015) Residential surface soil guidance applied worldwide to the pesticides added to the Stockholm Convention in 2009 and 2011. J Environ Manage 160: 226-240.
16. Jennings A, Li Z (2015) Residential surface soil guidance values applied worldwide to the original 2001 Stockholm Convention POP pesticides. J Environ Manage 160: 16-29.
17. Li Z, Jennings A (2017) Worldwide Regulations of Standard Values of Pesticides for Human Health Risk Control: A Review. Int J Environ Res Public Health 14: 826.
18. Agency for Toxic Substances and Disease Registry. Public Health Assessment Guidance Manual, 2005. Available from: http://www.atsdr.cdc.gov/hac/PHAManual/appg.html (accessed on 07.08.15).
19. U.S. Environmental Protection Agency. Regional Screening Levels (RSLs) – Generic Tables, May 2016. Available from: https://www.epa.gov/risk/regional-screening-levels-rsls-generic-tables-may-2016 (accessed on 7/30/2016).
20. Li Z (2016) Analysis of worldwide pesticide regulatory models and standards for controlling human health risk. Case Western Reserve University. Available from: https://etd.ohiolink.edu/.
21. World Health Organization (2003) 2,4-D in Drinking-water, background document for development of WHO Guidelines for Drinking-water Quality. Available from: http://www.who.int/water_sanitation_health/dwq/chemicals/24D.pdf (accessed on 07.30.16).
22. Federal Institute for Risk Assessment (2012) Reconsideration of the human toxicological reference values (ARfD, ADI) for Chlorpyrifos. Available from: http://www.bfr.bund.de/cm/349/reconsideration-of-the-human-toxicological-reference-values-arfd-adi-for-chlorpyrifos.pdf (accessed on 07.30.16).
23. Government of Canada (2009) Guidelines for Canadian Drinking Water Quality: Guideline Technical Document – Diazinon. Available from: http://healthycanadians.gc.ca/publications/healthy-living-vie-saine/water-diazinon-eau/index-eng.php (accessed on 07.30.16).

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Copyright Info: 2017, Zijian Li, et al., licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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