Export file:

Format

  • RIS(for EndNote,Reference Manager,ProCite)
  • BibTex
  • Text

Content

  • Citation Only
  • Citation and Abstract

Beneficial effects of antioxidative lactic acid bacteria

Department of Probiotics Immunology, Institute for Genetic Medicine, Hokkaido University, N15, W7, Kita-ku, Sapporo, Japan

Topical Section: Lactic Acid Bacteria: Genetics, Metabolism and Applications

Oxidative stress is caused by exposure to reactive oxygen intermediates. The oxidative damage of cell components such as proteins, lipids, and nucleic acids one of the important factors associated with diabetes mellitus, cancers and cardiovascular diseases. This occurs as a result of imbalance between the generations of oxygen derived radicals and the organism’s antioxidant potential. The amount of oxidative damage increases as an organism ages and is postulated to be a major causal factor of senescence. To date, many studies have focused on food sources, nutrients, and components that exert antioxidant activity in worms, flies, mice, and humans. Probiotics, live microorganisms that when administered in adequate amounts provide many beneficial effects on the human health, have been attracting growing interest for their health-promoting effects, and have often been administered in fermented milk products. In particular, lactic acid bacteria (LAB) are known to conferre physiologic benefits. Many studies have indicated the antioxidative activity of LAB. Here we review that the effects of lactic acid bacteria to respond to oxidative stress, is connected to oxidative-stress related disease and aging.
  Figure/Table
  Supplementary
  Article Metrics

References

1. Russell EG, Cotter TG (2015) Chapter Six-New Insight into the Role of Reactive Oxygen Species (ROS) in Cellular Signal-Transduction Processes. Int Rev Cell Mol Biol 319: 221–254.    

2. Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408: 239–247.    

3. Zommara M, Tachibana N, Sakono M, et al. (1996) Whey from cultured skim milk decreases serum cholesterol and increases antioxidant enzymes in liver and red blood cells in rats. Nutr Res 16: 293–302.    

4. Oxman T, Shapira M, Diver A, et al. (2000) A new method of long-term preventive cardioprotection usingLactobacillus. Am J Physiol Heart Circ Physiol 278: H1717–H1724.

5. Terahara M, Kurama S, Takemoto N (2001) Prevention by lactic acid bacteria of the oxidation of human LDL. Biosci Biotechnol Biochem 65: 1864–1868.

6. Kaizu H, Sasaki M, Nakajima H, et al. (1993) Effect of antioxidative lactic acid bacteria on rats fed a diet deficient in vitamin E. J Dairy Sci 76: 2493–2499.    

7. Rijkers GT, Bengmark S, Enck P, et al. (2010) Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research. J Nutr 140: 671s–676s.    

8. Ahotupa M, Saxelin M, Korpela R (1996) Antioxidative properties of Lactobacillus GG. Nutr Today 31: 51S.

9. Sun J, Hu XL, Le GW, et al. (2010) Lactobacilli prevent hydroxy radical production and inhibit Escherichia coli and Enterococcus growth in system mimicking colon fermentation. Lett Appl Microbiol 50: 264–269.    

10. Han W, Mercenier A, Aitbelgnaoui A, et al. (2006) Improvement of an experimental colitis in rats by lactic acid bacteria producing superoxide dismutase. Inflamm Bowel Dis 12: 1044–1052.    

11. LeBlanc JG, Del Carmen S, Miyoshi A, et al. (2011) Use of superoxide dismutase and catalase producing lactic acid bacteria in TNBS induced Crohn’s disease in mice. J Biotechnol 151: 287–293.    

12. Grompone G, Martorell P, Llopis S, et al. (2012) Anti-inflammatory Lactobacillus rhamnosus CNCM I-3690 strain protects against oxidative stress and increases lifespan in Caenorhabditis elegans. PLoS One 7: e52493.    

13. Guo Y, Pan D, Li H, et al. (2013) Antioxidant and immunomodulatory activity of selenium exopolysaccharide produced by Lactococcus lactis subsp. lactis. Food chem 138: 84–89.    

14. Mikelsaar M, Zilmer M (2009) Lactobacillus fermentum ME-3—an antimicrobial and antioxidative probiotic. Microb Ecol Health Dis 21: 1–27.

15. Zhang Y, Du R, Wang L, et al. (2010) The antioxidative effects of probiotic Lactobacillus casei Zhang on the hyperlipidemic rats. Eur Food Res Technol 231: 151–158.    

16. Kanno T, Kuda T, An C, et al. (2012) Radical scavenging capacities of saba-narezushi, Japanese fermented chub mackerel, and its lactic acid bacteria. LWT-Food Sci Technol 47: 25–30.    

17. Amaretti A, Di Nunzio M, Pompei A, et al. (2013) Antioxidant properties of potentially probiotic bacteria: in vitro and in vivo activities. Appl Microbiol Biotechnol 97: 809–817.

18. Park DY, Ahn YT, Park SH, et al. (2013) Supplementation of Lactobacillus curvatus HY7601 and Lactobacillus plantarum KY1032 in diet-induced obese mice is associated with gut microbial changes and reduction in obesity. PLoS One 8: e59470.    

19. Harman D (1955) Aging: a theory based on free radical and radiation chemistry.

20. López-Otín C, Blasco MA, Partridge L, et al. (2013) The hallmarks of aging. Cell 153: 1194–1217.    

21. Metchnikoff E, (1907) The prolongation of life: optimistic studies, London: William Heinemann, 161–183.

22. Yu X, Li S, Yang D, et al. (2016) A novel strain of Lactobacillus mucosae isolated from a Gaotian villager improves in vitro and in vivo antioxidant as well as biological properties in d-galactose-induced aging mice. J Dairy Sci 99: 903–914.    

23. Murphy CT, McCarroll SA, Bargmann CI, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277–283.    

24. Kim DH, Feinbaum R, Alloing G, et al. (2002) A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297: 623–626.    

25. Zugasti O, Ewbank JJ (2009) Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-β signaling pathway in Caenorhabditis elegans epidermis. Nat Immunol 10: 249–256.

26. So S, Tokumaru T, Miyahara K, et al. (2011) Control of lifespan by food bacteria, nutrient limitation and pathogenicity of food in C. elegans. Mech Ageing Dev 132: 210–212.

27. Hsu AL, Murphy CT, Kenyon C (2003) Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300: 1142–1145.    

28. Tullet JM, Hertweck M, An JH, et al. (2008) Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132: 1025–1038.    

29. Park SK, Tedesco PM, Johnson TE (2009) Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1. Aging cell 8: 258–269.    

30. Nakagawa H, Shiozaki T, Kobatake E, et al. (2015) Effects and mechanisms of prolongevity induced by Lactobacillus gasseri SBT2055 in Caenorhabditis elegans. Aging cell.

31. Hoeven R, McCallum KC, Cruz MR, et al. (2011) Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans. PLoS Pathog 7: e1002453.    

32. Inoue H, Hisamoto N, An JH, et al. (2005) The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev 19: 2278–2283.

33. Papp D, Csermely P, Sőti C (2012) A role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegans. PLoS pathog 8: e1002673.    

34. Aw D, Silva AB, Palmer DB (2007) Immunosenescence: emerging challenges for an ageing population. Immunology 120: 435–446.    

35. Ikeda T, Yasui C, Hoshino K, et al. (2007) Influence of lactic acid bacteria on longevity of Caenorhabditis elegans and host defense against salmonella enterica serovar enteritidis. Appl Environ Microbiol 73: 6404–6409.    

36. Lebeer S, Vanderleyden J, De Keersmaecker SC (2010) Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol 8: 171–184.

37. Konstantinov SR, Smidt H, de Vos WM, et al. (2008) S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. Proc Natl Acad Sci USA 105: 19474–19479.    

38. Kim Y, Kim SH (2009) Released exopolysaccharide (r-EPS) produced from probiotic bacteria reduce biofilm formation of enterohemorrhagic Escherichia coli O157: H7. Biochem Biophys Res Commun 379: 324–329.    

39. Kim Y, Oh S, Yun H, et al. (2010) Cell-bound exopolysaccharide from probiotic bacteria induces autophagic cell death of tumour cells. Lett Appl Microbiol 51: 123–130.

40. Kullisaar T, Zilmer M, Mikelsaar M, et al. (2002) Two antioxidative lactobacilli strains as promising probiotics. Int J Food Microbiol 72: 215–224.    

41. Kuda T, Kawahara M, Nemoto M, et al. (2014) In vitro antioxidant and anti-inflammation properties of lactic acid bacteria isolated from fish intestines and fermented fish from the Sanriku Satoumi region in Japan. Food Res Int 64: 248–255.

42. Castex M, Lemaire P, Wabete N, et al. (2010) Effect of probiotic Pediococcus acidilactici on antioxidant defences and oxidative stress of Litopenaeus stylirostris under Vibrio nigripulchritudo challenge. Fish Shellfish Immunol 28: 622–631.    

Copyright Info: © 2017, Tadaaki Miyazaki, et al., licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

Download full text in PDF

Export Citation

Article outline

Show full outline
Copyright © AIMS Press All Rights Reserved