Research article

Comparison of physical fitness in youth with post-COVID-19: A study of individuals with and without symptoms

  • Published: 22 October 2025
  • This study aims to examine differences in physical fitness among young adults in three distinct groups: individuals with long COVID, those who had recovered from COVID-19 without lingering symptoms, and healthy individuals with no history of infection. A total of 105 participants were equally divided into the three groups (n = 35 each). Evaluations included handgrip strength for upper body strength, handheld dynamometry for quadricep strength, and a six-minute walk test (6MWT) to assess the cardiorespiratory performance. Participants with long COVID demonstrated significantly lower handgrip strengths compared to the control group. Additionally, both post-COVID groups showed reduced 6MWT distances and elevated post-exercise physiological responses, including heart rate, systolic blood pressure, perceived exertion, and leg fatigue, regardless of symptom persistence. These findings indicate that individuals recovering from COVID-19, especially those with persistent symptoms, exhibit measurable declines in muscular and cardiorespiratory fitness, along with heightened physiological stress during physical activity.

    Citation: Patchareeya Amput, Sirima Wongphon. Comparison of physical fitness in youth with post-COVID-19: A study of individuals with and without symptoms[J]. AIMS Public Health, 2025, 12(4): 1026-1034. doi: 10.3934/publichealth.2025051

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  • This study aims to examine differences in physical fitness among young adults in three distinct groups: individuals with long COVID, those who had recovered from COVID-19 without lingering symptoms, and healthy individuals with no history of infection. A total of 105 participants were equally divided into the three groups (n = 35 each). Evaluations included handgrip strength for upper body strength, handheld dynamometry for quadricep strength, and a six-minute walk test (6MWT) to assess the cardiorespiratory performance. Participants with long COVID demonstrated significantly lower handgrip strengths compared to the control group. Additionally, both post-COVID groups showed reduced 6MWT distances and elevated post-exercise physiological responses, including heart rate, systolic blood pressure, perceived exertion, and leg fatigue, regardless of symptom persistence. These findings indicate that individuals recovering from COVID-19, especially those with persistent symptoms, exhibit measurable declines in muscular and cardiorespiratory fitness, along with heightened physiological stress during physical activity.



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    Acknowledgments



    We would like to thank all the volunteers who participated in this study. This research was supported by University of Phayao and Thailand Science Research and Innovation Fund (Fundamental Fund 2026, Grant No. 2264).

    Authors' contributions



    Conception and design: P Amput; Administrative support: P Amput; Provision of study materials or patients: P Amput, S Wongphon; Collection and assembly of data: P Amput, S Wongphon; Data analysis and interpretation: P Amput; Manuscript writing: All authors; Final approval of manuscript: All authors.

    Conflict of interest



    The authors declare no conflict of interest.

    [1] Soriano JB, Murthy S, Marshall JC, et al. (2022) A clinical case definition of post-COVID-19 condition by a Delphi consensus. Lancet Infect Dis 22: e102-e107. https://doi.org/10.1016/s1473-3099(21)00703-9
    [2] Nasserie T, Hittle M, Goodman SN (2021) Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review. JAMA Netw Open 4: e2111417. https://doi.org/10.1001/jamanetworkopen.2021.11417
    [3] Havervall S, Rosell A, Phillipson M, et al. (2021) Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers. JAMA 325: 2015-2016. https://doi.org/10.1001/jama.2021.5612
    [4] Halpin SJ, McIvor C, Whyatt G, et al. (2021) Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol 93: 1013-1022. https://doi.org/10.1002/jmv.26368
    [5] Aparisi Á, Ladrón R, Ybarra-Falcón C, et al. (2022) Exercise Intolerance in Post-Acute Sequelae of COVID-19 and the Value of Cardiopulmonary Exercise Testing- a Mini-Review. Front Med (Lausanne) 9: 924819. https://doi.org/10.3389/fmed.2022.924819
    [6] Lam GY, Befus AD, Damant RW, et al. (2021) Exertional intolerance and dyspnea with preserved lung function: an emerging long COVID phenotype?. Respir Res 22: 222. https://doi.org/10.1186/s12931-021-01814-9
    [7] Mustonen T, Kanerva M, Luukkonen R, et al. (2024) Cardiopulmonary exercise testing in long covid shows the presence of dysautonomia or chronotropic incompetence independent of subjective exercise intolerance and fatigue. BMC Cardiovasc Disord 24: 413. https://doi.org/10.1186/s12872-024-04081-w
    [8] Fernández-Lázaro D, Santamaría G, Sánchez-Serrano N, et al. (2022) Efficacy of Therapeutic Exercise in Reversing Decreased Strength, Impaired Respiratory Function, Decreased Physical Fitness, and Decreased Quality of Life Caused by the Post-COVID-19 Syndrome. Viruses 14: 2797. https://doi.org/10.3390/v14122797
    [9] Fernández-Lázaro D, Santamaría G, Sánchez-Serrano N, et al. (2021) Long COVID a New Derivative in the Chaos of SARS-CoV-2 Infection: The Emergent Pandemic?. J Clin Med 10: 5799. https://doi.org/10.3390/jcm10245799
    [10] Amput P, Tapanya W, Sangkarit N, et al. (2023) Balance Ability and Quality of Life in Older Adult with Recovery from Mild COVID-19. Ann Geriatr Med Res 27: 235-240. https://doi.org/10.4235/agmr.23.0084
    [11] Amput P, Wongphon S (2024) Follow-Up of Cardiopulmonary Responses Using Submaximal Exercise Test in Older Adults with Post-COVID-19. Ann Geriatr Med Res 28: 476-483. https://doi.org/10.4235/agmr.24.0093
    [12] Amput P, Wongphon S (2024) The Assessment of Muscle Strength and Cardiorespiratory Parameters Using Simple Tests in Older Adults With Recovery From Mild COVID-19. Ann Rehabil Med 48: 389-95. https://doi.org/10.5535/arm.240033
    [13] Jamieson A, Al Saikhan L, Alghamdi L, et al. (2024) Mechanisms underlying exercise intolerance in long COVID: An accumulation of multisystem dysfunction. Physiol Rep 12: e15940. https://doi.org/10.14814/phy2.15940
    [14] Salmam I, Perreault K, Best KL, et al. (2025) Physical impairments in individuals with Long COVID. Front Sports Act Living 7: 1511942. https://doi.org/10.3389/fspor.2025.1511942
    [15] Horn K, Johnson H, Williams E, et al. (2024) Validity and reliability of the takei hand dynamometer. Int J Exerc Sci: Conf Proc 16: 130.
    [16] Savas S, Kilavuz A, Kayhan Koçak F, et al. (2023) Comparison of Grip Strength Measurements by Widely Used Three Dy-namometers in Outpatients Aged 60 Years and Over. J Clin Med 12: 4260. https://doi.org/10.3390/jcm12134260
    [17] Mentiplay BF, Perraton LG, Bower KJ, et al. (2015) Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study. PLoS One 10: e0140822. https://doi.org/10.1371/journal.pone.0140822
    [18] Brown LE, Weir JP (2001) ASEP procedures recommendation I: accurate assessment of muscular strength and power. J Exerc Physiol Online 4: 1-21.
    [19] ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories.ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med (2002) 166: 111-117. https://doi.org/10.1164/ajrccm.166.1.at1102
    [20] Disser NP, De Micheli AJ, Schonk MM, et al. (2020) Musculoskeletal Consequences of COVID-19. J Bone Joint Surg Am 102: 1197-1204. https://doi.org/10.2106/jbjs.20.00847
    [21] Montes-Ibarra M, Oliveira CLP, Orsso CE, et al. (2022) The Impact of Long COVID-19 on Muscle Health. Clin Geriatr Med 38: 545-557. https://doi.org/10.1016/j.cger.2022.03.004
    [22] Belli S, Balbi B, Prince I, et al. (2020) Low physical functioning and impaired performance of activities of daily life in COVID-19 patients who survived hospitalisation. Eur Respir J 56: 2002096. https://doi.org/10.1183/13993003.02096-2020
    [23] Zampogna E, Paneroni M, Belli S, et al. (2021) Pulmonary Rehabilitation in Patients Recovering from COVID-19. Respiration 100: 416-422. https://doi.org/10.1159/000514387
    [24] Del Valle DM, Kim-Schulze S, Huang HH, et al. (2020) An inflammatory cytokine signa-ture predicts COVID-19 severity and survival. Nat Med 26: 1636-1643. https://doi.org/10.1038/s41591-020-1051-9
    [25] Molnar T, Lehoczki A, Fekete M, et al. (2024) Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches. Geroscience 46: 5267-5286. https://doi.org/10.1007/s11357-024-01165-5
    [26] Shang C, Liu Z, Zhu Y, et al. (2021) SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment. Front Microbiol 12: 780768. https://doi.org/10.3389/fmicb.2021.780768
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