The refractive index of human blood measured at the visible spectral region by single-fiber reflectance spectroscopy

Mohamed A. Elblbesy; Mohamed A. Elblbesy

doi:10.3934/biophy.2021004

AIMS Biophysics

2021, Volume 8, Issue 1: 57-65. doi: 10.3934/biophy.2021004

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The refractive index of human blood measured at the visible spectral region by single-fiber reflectance spectroscopy

Mohamed A. Elblbesy ^{1,2
,
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1.
Department of Medical Biophysics, Medical Research Institute, Alexandria University, Alexandria 21561, Egypt
2.
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk 71491, Saudi Arabia

Received: 17 October 2020 Accepted: 14 December 2020 Published: 17 December 2020

The refractive index is an essential biophysical parameter used in many diagnostic and therapeutic biomedical applications. In the present study, the refractive index of control and anemic blood was measured using the total internal reflection fiber optics technique. For control, the refractive index measured by the indicated method was significantly higher than anemic blood over the wavelengths in the visible spectral region used in this study. Strong linear correlations between refractive index and hemoglobin concentration were obtained for control and anemic blood. These findings could enhance the use of the refractive index in many applications of blood analysis and hematology.
- refractive index,
- visible spectra,
- anemia,
- blood
Citation: Mohamed A. Elblbesy. The refractive index of human blood measured at the visible spectral region by single-fiber reflectance spectroscopy[J]. AIMS Biophysics, 2021, 8(1): 57-65. doi: 10.3934/biophy.2021004

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Abstract

The refractive index is an essential biophysical parameter used in many diagnostic and therapeutic biomedical applications. In the present study, the refractive index of control and anemic blood was measured using the total internal reflection fiber optics technique. For control, the refractive index measured by the indicated method was significantly higher than anemic blood over the wavelengths in the visible spectral region used in this study. Strong linear correlations between refractive index and hemoglobin concentration were obtained for control and anemic blood. These findings could enhance the use of the refractive index in many applications of blood analysis and hematology.

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