Mathematical Biosciences and Engineering, 2007, 4(4): 609-615. doi: 10.3934/mbe.2007.4.609.

Primary: 92B05, 60G55; Secondary: 92C30.

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Improved integrate-and-fire model for RSA

1. Istituto di Biofisica, CNR, Via G. Moruzzi 1, 56124 - Pisa
2. Istituto di Fisiologia Clinica, CNR, Via G. Moruzzi 1, 56124 - Pisa


A simple operational model of heart rate variability is described, accounting in particular for the respiratory sinus arrhythmia, and is fitted to some interbeat interval sequences recorded from normal subjects at rest. The model performance is evaluated using a test based on the nonlinear prediction approach. Moreover, a short comparative account of two similar models described in the literature is given.
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Keywords heartbeat; tachogram; respiratory sinus arrhythmia.; stochastic operational model

Citation: Michele Barbi, Angelo Di Garbo, Rita Balocchi. Improved integrate-and-fire model for RSA. Mathematical Biosciences and Engineering, 2007, 4(4): 609-615. doi: 10.3934/mbe.2007.4.609


This article has been cited by

  • 1. Alona Ben-Tal, Sophie S. Shamailov, Julian F.R. Paton, Central regulation of heart rate and the appearance of respiratory sinus arrhythmia: New insights from mathematical modeling, Mathematical Biosciences, 2014, 255, 71, 10.1016/j.mbs.2014.06.015

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