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Integrative medicinal approaches towards Alzheimer's disease model animals–A new hope

  • Received: 30 January 2024 Revised: 29 April 2024 Accepted: 13 May 2024 Published: 05 June 2024
  • Alzheimer's disease (AD), a neurodegenerative disease (ND), has been plaguing healthcare and health policy agencies due to its ever-soaring impact globally. It is timely to develop appropriate measures to combat global AD burden. Due to structural and functional similarity, rodent models offer the best alternative to study AD pathogenesis and therapeutics. In this special issue, the present article reviews the state-of-the-art findings on AD model animals from the alternative and integrative medicinal point of view. Our integrative therapeutic agents include fungi (Ganoderma lucidum), turmeric (Curcuma longa), Indian black berry (black plum, jamun) (Syzygium cumini), and madecassoside (derived from Centella asiatica). Their bio-components, especially flavonoids, polyphenols, and tri-terpenoids, resist oxidative stress, amyloid beta fibrillation, and pro-inflammatory cytokine levels; improve anti-oxidative prowess; and improve learning-related memory and anxiety-like behavior in AD model animals. Most of the findings described here are outcomes of our own studies. However, our claims have been substantiated with evidence from some other studies in the relevant field. As a whole, integrative medicinal approaches towards AD pathogenesis using these natural products seem promising in AD protection.

    Citation: Shahdat Hossain, Mohammad Azizur Rahman, Shoriful Islam Joy, Anuradha Baraik, Shadman Nazib. Integrative medicinal approaches towards Alzheimer's disease model animals–A new hope[J]. AIMS Molecular Science, 2024, 11(3): 221-230. doi: 10.3934/molsci.2024013

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  • Alzheimer's disease (AD), a neurodegenerative disease (ND), has been plaguing healthcare and health policy agencies due to its ever-soaring impact globally. It is timely to develop appropriate measures to combat global AD burden. Due to structural and functional similarity, rodent models offer the best alternative to study AD pathogenesis and therapeutics. In this special issue, the present article reviews the state-of-the-art findings on AD model animals from the alternative and integrative medicinal point of view. Our integrative therapeutic agents include fungi (Ganoderma lucidum), turmeric (Curcuma longa), Indian black berry (black plum, jamun) (Syzygium cumini), and madecassoside (derived from Centella asiatica). Their bio-components, especially flavonoids, polyphenols, and tri-terpenoids, resist oxidative stress, amyloid beta fibrillation, and pro-inflammatory cytokine levels; improve anti-oxidative prowess; and improve learning-related memory and anxiety-like behavior in AD model animals. Most of the findings described here are outcomes of our own studies. However, our claims have been substantiated with evidence from some other studies in the relevant field. As a whole, integrative medicinal approaches towards AD pathogenesis using these natural products seem promising in AD protection.



    Dubrovin [1] invented the notion of Frobenius manifolds in order to give geometrical expressions associated with WDVV equations. In 1999, Hertling and Manin [2] introduced the concept of F-manifolds as a relaxation of the conditions of Frobenius manifolds. Inspired by the investigation of describing F-manifolds algebraically, Dotsenko [3] defined F-manifold algebras in 2019 to relate operad F-manifold algebras to operad pre-Lie algebras. By definition, an F-manifold algebra is a triple (F,,[,]) satisfying the following Hertling–Manin relation:

    Hx1x2(x3,x4)=x1Hx2(x3,x4)+x2Hx1(x3,x4),   x1,x2,x3,x4F,

    where (F,) is a commutative associative algebra, (F,[,]) is a Lie algebra, and Hx1(x2,x3)=[x1,x2x3][x1,x2]x3x2[x1,x3].

    A vector space F admitting a linear map is called a pre-Lie algebra if the following holds:

    (x1x2)x3x1(x2x3)=(x2x1)x3x2(x1x3),   x1,x2,x3F.

    In recent years, pre-Lie algebras have attracted a great deal of attention in many areas of mathematics and physics (see [4,5,6,7] and so on).

    Liu et al. [8] introduced the concept of pre-F-manifold algebras. Note that these algebras allow us to construct F-manifold algebras. They also studied representations of F-manifold algebras and constructed many other examples of these algebras. The definition of super F-manifold algebras and related categories was stated by Cruz Morales et al. [9]. Chen et al. [10] discussed the classification of three-dimensional F-manifold algebras over the complex field C, which was based on the results of the classifications of low-dimensional commutative associative algebras and low-dimensional Lie algebras. Recently, the concept of Hom-F-manifold algebras and their properties have been given by Ben Hassine et al. [11].

    In this paper, we provide the concepts of an F-manifold color algebra and a pre-F-manifold color algebra, respectively. We extend some properties of F-manifold algebras that were obtained in [8] to the color case. In Section 2, we summarize some concepts of Lie color algebras, pre-Lie color algebras, and representations of χ-commutative associative algebras and Lie color algebras, respectively. In Section 3, we provide the concept of an F-manifold color algebra and then study its representation. The concept of a coherence F-manifold color algebra is also introduced, and it follows that an F-manifold color algebra admitting a non-degenerate symmetric bilinear form is a coherence F-manifold color algebra. The concept of pre-F-manifold color algebras is defined in Section 4, and using these algebras, one can construct F-manifold color algebras.

    Throughout this paper, we assume that k is a field with char k=0 and all vector spaces are finite dimensional over k.

    A preprint of this paper was posted on arXiv [12].

    The concept of a Lie color algebra was introduced in [13] and systematically studied in [14]. Since then, Lie color algebras have been studied from different aspects: Lie color ideals [15], generalized derivations [16], representations [17,18], T-extensions of Lie color algebras [19,20] and hom-Lie color algebras [21], cohomology groups [22] and the color left-symmetric structures on Lie color algebras [23]. In this section, we collect some basic definitions that will be needed in the remainder of the paper. In the following, we assume that G is an abelian group and denote k{0} by k.

    Definition 2.1. A skew-symmetric bicharacter is a map χ:G×Gk satisfying

    (i) χ(g1,g2)=χ(g2,g1)1,

    (ii) χ(g1,g2)χ(g1,g3)=χ(g1,g2+g3),

    (iii) χ(g1,g3)χ(g2,g3)=χ(g1+g2,g3),

    for all g1,g2,g3G.

    By the definition, it is obvious that for anyaG, we have χ(a,0)=χ(0,a)=1 and χ(a,a)=±1.

    Definition 2.2. A pre-Lie color algebra is the G-graded vector space

    F=gGFg

    with a bilinear multiplication operation satisfying

    1) Fg1Fg2Fg1+g2,

    2) (x1x2)x3x1(x2x3)=χ(g1,g2)((x2x1)x3x2(x1x3)),

    for all x1Fg1,x2Fg2,x3Fg3, and g1,g2,g3G.

    Definition 2.3. A Lie color algebra is the G-graded vector space

    F=gGFg

    with a bilinear multiplication [,] satisfying

    (i) [Fg1,Fg2]Fg1+g2,

    (ii) [x1,x2]=χ(g1,g2)[x2,x1],

    (iii) χ(g3,g1)[x1,[x2,x3]]+χ(g1,g2)[x2,[x3,x1]]+χ(g2,g3)[x3,[x1,x2]]=0,

    for all x1Fg1,x2Fg2,x3Fg3, and g1,g2,g3G.

    Remark Given a pre-Lie algebra (F,), if we define the bracket [x1,x2]=x1x2x2x1, then (F,[,]) becomes a Lie algebra. Similarly, one has a pre-Lie color algebra's version, that is to say, a pre-Lie color algebra (A,,χ) with the bracket [x1,x2]=x1x2χ(x1,x2)x2x1 becomes a Lie color algebra.

    Let the vector space F be G-graded. An element xF is called homogeneous with degree gG if xFg. In the rest of this paper, for any x1Fg1,x2Fg2,x3Fg3, we will write χ(x1,x2) instead of χ(g1,g2), χ(x1+x2,x3) instead of χ(g1+g2,g3), and so on. Furthermore, when we write the skew-symmetric bicharacter χ(x1,x2), it is always assumed that the elements x1 and x2 are both homogeneous.

    For a χ-commutative associative algebra (F,,χ), we mean that (F,) is a G-graded associative algebra with the following χ-commutativity:

    x1x2=χ(x1,x2)x2x1

    for all x1Fg1 and x2Fg2.

    Now, we assume that the vector space V is G-graded. A representation (V,μ) of the algebra (F,,χ) is a linear map μ:FEndk(V)G:=gGEndk(V)g satisfying

    μ(x2)vVg1+g2,    μ(x2x3)=μ(x2)μ(x3)

    for all vVg1,x2Fg2,x3Fg3, where Endk(V)g:={fEndk(V)|f(Vh)Vh+g}. Given a Lie color algebra (F,[,],χ), its representation (V,ρ) is a linear map ρ:FEndk(V)G satisfying

    ρ(x2)vVg1+g2,    ρ([x2,x3])=ρ(x2)ρ(x3)χ(x2,x3)ρ(x3)ρ(x2)

    for all vVg1,x2Fg2,x3Fg3.

    The dual space V=gGVg is also G-graded, where

    Vg1={ξV|ξ(x)=0,g2g1,xVg2,g2G}.

    Define a linear map μ:FEndk(V)G satisfying

    μ(x1)ξVg1+g3,    μ(x1)ξ,v=χ(x1,ξ)ξ,μ(x1)v

    for all x1Fg1,vVg2,ξVg3.

    It is easy to see that

    1) If (V,μ) is one representation of the algebra (F,,χ), then (V,μ) is also its representation;

    2) If (V,μ) is one representation of the algebra (F,[,],χ), then (V,μ) is also its representation.

    The concept of F-manifold color algebras is presented, and some results in [8] to the color case are established.

    Definition 3.1. Let (F,[,],χ) be a Lie color algebra and (F,,χ) be a χ-commutative associative algebra. A quadruple (F,,[,],χ) is called an F-manifold color algebra if the following holds for any homogeneous element x1,x2,x3,x4F,

    Hx1x2(x3,x4)=x1Hx2(x3,x4)+χ(x1,x2)x2Hx1(x3,x4), (3.1)

    where Hx1(x2,x3) is the color Leibnizator given by

    Hx1(x2,x3)=[x1,x2x3][x1,x2]x3χ(x1,x2)x2[x1,x3]. (3.2)

    Remark It is noticed that if we set G={0} and χ(0,0)=1, then (F,,[,],χ) is exactly an F-manifold algebra.

    Definition 3.2. Let (F,,[,],χ) be an F-manifold color algebra, (V,μ) be a representation of the algebra (F,,χ), and (V,ρ) be a representation of the algebra (F,[,],χ). A representation of (F,,[,],χ) is a triple (V,ρ,μ) if the following holds for any homogeneous element x1,x2,x3F,

    M1(x1x2,x3)=μ(x1)M1(x2,x3)+χ(x1,x2)μ(x2)M1(x1,x3),μ(Hx1(x2,x3))=χ(x1,x2+x3)M2(x2,x3)μ(x1)μ(x1)M2(x2,x3),

    where the linear maps M1 and M2 from FF to Endk(V)G are given by

    M1(x1,x2)=ρ(x1)μ(x2)χ(x1,x2)μ(x2)ρ(x1)μ([x1,x2]), (3.3)
    M2(x1,x2)=μ(x1)ρ(x2)+χ(x1,x2)μ(x2)ρ(x1)ρ(x1x2). (3.4)

    Example 3.1. Let (F,,[,],χ) be an F-manifold color algebra. We have that (F,ad,L) is a representation of (F,,[,],χ), where ad:FEndk(F)G is given by

    adx1x2=[x1,x2]

    and the left multiplication operator L:FEndk(F)G is given by

    Lx1x2=x1x2

    for any homogeneous element x1,x2F.

    Proof. Note that (F,L) is a representation of the algebra (F,,χ) and (F,ad) is a representation of the algebra (F,[,],χ).

    Now, for any homogeneous element x1,x2,x3,x4F, we obtain

    M1(x1,x2)x3=(adx1Lx2χ(x1,x2)Lx2adx1L[x1,x2])x3=[x1,x2x3]χ(x1,x2)x2[x1,x3][x1,x2]x3=Hx1(x2,x3).

    Thus

    Hx1x2(x3,x4)=x1Hx2(x3,x4)+χ(x1,x2)x2Hx1(x3,x4)

    implies the equation

    M1(x1x2,x3)x4=Lx1M1(x2,x3)x4+χ(x1,x2)Lx2M1(x1,x3)x4.

    On the other hand, we obtain

    M2(x2,x3)x4=(Lx2adx3+χ(x2,x3)Lx3adx2adx2x3)x4=x2[x3,x4]+χ(x2,x3)x3[x2,x4][x2x3,x4]=χ(x3,x4)x2[x4,x3]χ(x2,x4)χ(x3,x4)[x4,x2]x3+χ(x2+x3,x4)[x4,x2x3]=χ(x2+x3,x4)([x4,x2x3][x4,x2]x3χ(x4,x2)x2[x4,x3])=χ(x2+x3,x4)Hx4(x2,x3).

    Thus

    χ(x1,x2+x3)M2(x2,x3)Lx1x4Lx1M2(x2,x3)x4=χ(x1,x2+x3)M2(x2,x3)(x1x4)xM2(x2,x3)x4=χ(x1,x2+x3)χ(x2+x3,x1+x4)Hx1x4(x2,x3)χ(x2+x3,x4)x1Hx4(x2,x3)=χ(x2+x3,x4){Hx1x4(x2,x3)xHx4(x2,x3)}=χ(x2+x3,x4)χ(x1,x4)x4Hx1(x2,x3)=χ(x1+x2+x3,x4)x4Hx1(x2,x3)=Hx1(x2,x3)x4.

    Hence, the proof is completed.

    Let (V,ρ,μ) be a representation of the F-manifold color algebra (F,,[,],χ). Note that FV is a G-graded vector space. In the following, if we write x+vFV as a homogeneous element for xF,vV, it means that x and v are of the same degree as x+v. Now assume that x1+v1 and x2+v2 are both homogeneous elements in FV. Define

    [x1+v1,x2+v2]ρ=[x1,x2]+ρ(x1)v2χ(x1,x2)ρ(x2)v1.

    Then we obtain that (FV,[,]ρ,χ) is a Lie color algebra. Moreover, define

    (x1+v1)μ(x2+v2)=x1x2+μ(x1)v2+χ(x1,x2)μ(x2)v1.

    It is easy to see that (FV,μ,χ) is a χ-commutative associative algebra. In fact, we have

    Proposition 3.2. With the above notations, (FV,μ,[,]ρ,χ) is an F-manifold color algebra.

    Proof. It is sufficient to check that the relation in Definition 3.1 holds.

    For any homogeneous element x1+v1,x2+v2,x3+v3FV, we have

    Hx1+v1(x2+v2,x3+v3)=[x1+v1,(x2+v2)μ(x3+v3)]ρ[x1+v1,x2+v2]ρμ(x3+v3)χ(x1,x2)(x2+v2)μ[x1+v1,x3+v3]ρ=[x1,x2x3]+ρ(x1){μ(x2)v3+χ(x2,x3)μ(x3)v2}χ(x1,x2+x3)ρ(x2x3)v1III.

    where

    I={[x1,x2]+ρ(x1)v3χ(x1,x2)ρ(x2)v1}μ(x3+v3)=[x1,x2]x3+μ([x1,x2])v3+χ(x1+x2,x3)μ(x3){ρ(x1)v2χ(x1,x2)ρ(x2)v1},

    and

    II=χ(x1,x2)(x2+v2)μ{[x1,x3]+ρ(x1)v3χ(x1,x3)ρ(x3)v1}=χ(x1,x2){x2[x1,x3]+μ(x2)(ρ(x1)v3χ(x1,x3)ρ(x3)v1)+χ(x2,x1+x3)μ([x1,x3])v2}.

    Thus

    Hx1+v1(x2+v2,x3+v3)=Hx1(x2,x3)+{ρ(x1)μ(x2)μ([x1,x2])χ(x1,x2)μ(x2)ρ(x1)}v3+{χ(x2,x3)ρ(x1)μ(x3)χ(x1+x2,x3)μ(x3)ρ(x1)χ(x1,x2)χ(x2,x1+x3)μ([x1,x3])}v2+{χ(x1,x2+x3)ρ(x2x3)+χ(x1+x2,x3)χ(x1,x2)μ(x3)ρ(x2)+χ(x1,x2)χ(x1,x3)μ(x2)ρ(x3)}v1=Hx1(x2,x3)+M1(x1,x2)v3+χ(x2,x3)M1(x1,x3)v2+χ(x1,x2+x3)M2(x2,x3)v1.

    Hence, for any homogeneous element x4+v4FV, we have

    H(x1+v1)μ(x2+v2)(x3+v3,x4+v4)=Hx1x2+μ(x1)v2+χ(x1,x2)μ(x2)v1(x3+v3,x4+v4)=Hx1x2(x3,x4)+M1(x1x2,x3)v4+χ(x3,x4)M1(x1x2,x4)v3+χ(x1+x2,x3+x4)M2(x3,x4)(μ(x1)v2+χ(x1,x2)μ(x2)v1).

    On the other hand

    (x1+v1)μHx2+v2(x3+v3,x4+v4)=(x1+v1)μ{Hx2(x3,x4)+M1(x2,x3)v4+χ(x3,x4)M1(x2,x4)v3+χ(x2,x3+x4)M2(x3,x4)v2}=x1Hx2(x3,x4)+μ(x1){M1(x2,x3)v4+χ(x3,x4)M1(x2,x4)v3+χ(x2,x3+x4)M2(x3,x4)v2}+χ(x1,x2+x3+x4)μ(Hx2(x3,x4))v1,

    and

    χ(x1,x2)(x2+v2)μHx1+v1(x3+v3,x4+v4)=χ(x1,x2){x2Hx1(x3,x4)+μ(x2){M1(x1,x3)v4+χ(x3,x4)M1(x1,x4)v3+χ(x1,x3+x4)M2(x3,x4)v1}+χ(x2,x1+x3+x4)μ(Hx1(x3,x4))v2}.

    Thus

    (x1+v1)μHx2+v2(x3+v3,x4+v4)+χ(x1,x2)(x2+v2)μHx1+v1(x3+v3,x4+v4)=x1Hx2(x3,x4)+χ(x1,x2)x2Hx1(x3,x4)+{μ(x1)M1(x2,x3)+χ(x1,x2)μ(x2)(M1(x1,x3))}v4+{χ(x3,x4)μ(x1)M1(x2,x4)+χ(x1,x2)χ(x3,x4)μ(x2)M1(x1,x4)}v3+{χ(x2,x3+x4)μ(x1)M2(x3,x4)+χ(x1,x2)χ(x2,x1+x3+x4)μ(Hx1(x3,x4))}v2+χ(x1,x2+x3+x4){μ(x2)M2(x3,x4)+μ(Hx2(x3,x4))}v1=H(x1+v1)μ(x2+v2)(x3+v3,x4+v4),

    which satisfies the relation in Definition 3.1. Hence, the conclusion follows immediately.

    It is noticed that, given a representation (V,ρ,μ) of an F-manifold algebra, Liu, Sheng, and Bai [8] asserted that (V,ρ,μ) may not be its representation. Now, assume that (F,,[,],χ) is an F-manifold color algebra, together with a representation (V,μ) of the algebra (F,,χ) and a representation (V,ρ) of the algebra (F,[,],χ). In order to prove the following proposition associated with an F-manifold color algebra, we need to define the linear map M3 from FF to Endk(V)G by

    M3(x1,x2)=χ(x1,x2)ρ(x2)μ(x1)ρ(x1)μ(x2)+ρ(x1x2),

    and the linear maps M1,M2 from FF to Endk(V)G by

    M1(x1,x2)=ρ(x1)μ(x2)+χ(x1,x2)μ(x2)ρ(x1)+μ([x1,x2]),M2(x1,x2)=μ(x1)ρ(x2)χ(x1,x2)μ(x2)ρ(x1)ρ(x1x2)

    for any homogeneous element x1,x2F.

    Proposition 3.3. With the above notations, assume that for any homogeneous element x1,x2,x3F, the following holds:

    M1(x1x2,x3)=χ(x1,x2+x3)M1(x2,x3)μ(x1)+χ(x2,x3)M1(x1,x3)μ(x2),μ(Hx1(x2,x3))=χ(x1,x2+x3)M3(x2,x3)μ(x1)+μ(x1)M3(x2,x3).

    Then (V,ρ,μ) is a representation of (F,,[,],χ).

    Proof. Suppose that x1,x2,x3F,vV,ξV are all homogeneous elements. First, we claim the following two identities:

    M1(x1,x2)(ξ),v=ξ,χ(x1+x2,ξ)M1(x1,x2)v;M2(x1,x2)(ξ),v=ξ,χ(x1+x2,ξ)M3(x1,x2)v.

    The claims follow from some direct calculations, respectively:

    M1(x1,x2)(ξ),v=(ρ(x1)μ(x2)+χ(x1,x2)μ(x2)ρ(x1)+μ([x1,x2]))ξ,v=χ(x1,x2+ξ)μ(x2)ξ,ρ(x1)vχ(x1,x2)χ(x2,x1+ξ)(ρ(x1)ξ,μ(x2)vχ(x1+x2,ξ)ξ,μ([x1,x2])v=χ(x1,x2)χ(x1+x2,ξ)ξ,μ(x2)ρ(x1)v+χ(x2,ξ)χ(x1,ξ)ξ,ρ(x1)μ(x2)vχ(x1+x2,ξ)ξ,μ([x1,x2])v=ξ,χ(x1+x2,ξ){χ(x1,x2)μ(x2)ρ(x1)+ρ(x1)μ(x2)μ([x1,x2])}v=ξ,χ(x1+x2,ξ)M1(x1,x2)v,

    and

    M2(x1,x2)(ξ),v={μ(x1)ρ(x2)χ(x1,x2)μ(x2)ρ(x1)ρ(x1x2)}ξ,v=χ(x1,x2+ξ)χ(x2,ξ)ξ,ρ(x2)μ(x1)vχ(x2,ξ)χ(x1,ξ)ξ,ρ(x1)μ(x2)v+χ(x1+x2,ξ)ξ,ρ(x1x2)v=ξ,χ(x1+x2,ξ){χ(x1,x2)ρ(x2)μ(x1)ρ(x1)μ(x2)+ρ(x1x2)}v=ξ,χ(x1+x2,ξ)M3(x1,x2)v.

    With the above identities, we have

    {M1(x1x2,x3)+μ(x1)M1(x2,x3)+χ(x1,x2)μ(x2)M1(x1,x3)}ξ,v=ξ,χ(x1+x2+x3,ξ)M1(x1x2,x3)vχ(x1,x2+x3+ξ)χ(x2+x3,ξ)ξ,M1(x2,x3)μ(x1)vχ(x1+x3,ξ)χ(x2,x3+ξ)ξ,M1(x1,x3)μ(x2)v=χ(x1+x2+x3,ξ)ξ,{M1(x1x2,x3)χ(x1,x2+x3)M1(x2,x3)μ(x1)χ(x2,x3)M1(x1,x3)μ(x2)}v=0,

    and

    {μ(Hx1(x2,x3))+χ(x1,x2+x3)M2(x2,x3)μ(x1)μ(x1)M2(x2,x3)}ξ,v=χ(x1+x2+x3,ξ)ξ,μ(Hx1(x2,x3))v+χ(x1,x2+z)χ(x2+x3,x1+ξ)μ(x1)ξ,M3(x2,x3)v+χ(x1,x2+x3+ξ)M2(x2,x3)ξ,μ(x1)v=χ(x1+x2+x3,ξ)ξ,μ(Hx1(x2,x3))vχ(x2+x3,ξ)χ(x,ξ)ξ,μ(x1)M3(x2,x3)v+χ(x,x2+x3+ξ)χ(x2+x3,ξ)ξ,M3(x2,x3)μ(x1)v=χ(x1+x2+x3,ξ)ξ,{μ(Hx1(x2,x3))μ(x1)M3(x2,x3)+χ(x1,x2+x3)M3(x2,x3)μ(x1)}v=0.

    Therefore, the conclusion follows immediately from the hypothesis and Definition 3.2.

    Given an F-manifold color algebra (F,,[,],χ), we define the linear map T from FF to Endk(F)G by

    T(x1,x2)(x3)=χ(x1,x2)[x2,x1x3][x1,x2x3]+[x1x2,x3]

    for any homogeneous elements x1,x2,x3F.

    Definition 3.3. An F-manifold color algebra (F,,[,],χ) is called a coherence one if for any homogeneous elements x1,x2,x3,x4F, the following hold:

    Hx1x2(x3,x4)=χ(x1,x2+x3)Hx2(x3,x1x4)+χ(x2,x3)Hx1(x3,x2x4),Hx1(x2,x3)x4=χ(x1,x2+x3)T(x2,x3)(x1x4)+x1T(x2,x3)(x4).

    Proposition 3.4. Assume that (,) is a non-degenerate symmetric bilinear form on the F-manifold color algebra (F,,[,],χ) satisfying

    (x1x2,x3)=(x1,x2x3)  and  ([x1,x2],x3)=(x1,[x2,x3])

    for any homogeneous elements x1,x2,x3F. Then (F,,[,],χ) is a coherence F-manifold color algebra.

    Proof. First, we prove that

    (Hx1(x2,x3),x4)=χ(x1+x2,x3)(x3,Hx1(x2,x4))

    for any homogeneous elements x1,x2,x3,x4F.

    In fact, we obtain

    (Hx1(x2,x3),x4)=([x1,x2x3][x1,x2]x3χ(x1,x2)x2[x1,x3],x4)=χ(x1,x2+x3)([x2x3,x1],x4)χ(x1+x2,x3)(x3,[x1,x2]x4)χ(x1,x2)χ(x2,x1+x3)([x1,x3],x2x4)=χ(x1,x2+x3)(x2x3,[x1,x4])χ(x1+x2,x3)(x3,[x1,x2]x4)+χ(x2,x3)χ(x1,x3)(x3,[x1,x2x4])=χ(x1,x2+x3)χ(x2,x3)(x3,x2[x1,x4])χ(x1+x2,x3)(x3,[x1,x2]x4)+χ(x1+x2,x3)(x3,[x1,x2x4])=χ(x1+x2,x3)(x3,χ(x1,x2)x2[x1,x4][x1,x2]x4+[x1,x2x4])=χ(x1+x2,x3)(x3,Hx1(x2,x4)).

    By the above relation, for every homogeneous element x1,x2,x3,w1,w2F, we have

    (Hx1x2(x3,w1)χ(x1,x2+x3)Hx2(x3,x1w1)χ(x2,x3)Hx1(x3,x2w1),w2)=χ(x1+x2+x3,w1)(w1,Hx1x2(x3,w2))χ(x1,x2+x3)χ(x2+x3,x1+w1)(x1w1,Hx2(x3,w2))χ(x2,x3)χ(x1+x3,x2+w1)(x2w1,Hx1(x3,w2))=χ(x1+x2+x3,w1)(w1,Hx1x2(x3,w2))χ(x1,x2+x3)χ(x2+x3,x1+w1)χ(x1,w1)(w1,x1Hx2(x3,w2))χ(x2,x3)χ(x1+x3,x2+w1)χ(x2,w1)(w1,x2Hx1(x3,w2))=χ(x1+x2+x3,w1)(w1,Hx1x2(x3,w2))χ(x1+x2+x3,w1)(w1,x1Hx2(x3,w2))χ(x2,x3)χ(x1+x3,x2)χ(x1+x2+x3,w1)(w1,x2Hx1(x3,w2))=χ(x1+x2+x3,w1)(w1,Hx1x2(x3,w2))χ(x1+x2+x3,w1)(w1,x1Hx2(x3,w2))χ(x1,x2)χ(x1+x2+x3,w1)(w1,x2Hx1(x3,w2))=χ(x1+x2+x3,w1)(w1,Hx1x2(x3,w2)x1Hx2(x3,w2)χ(x1,x2)x2Hx1(x3,w2))=0.

    We claim the following identity:

    (T(x2,x3)(w1),w2)=χ(x2+x3,w1+w2)(w1,Hw2(x2,x3)).

    In fact, we have

    (T(x2,x3)(w1),w2)=(χ(x2,x3)[x3,x2w1][x2,x3w1]+[x2x3,w1],w2)=χ(x2,x3)χ(x3,x2+w1)(x2w1,[x3,w2])+χ(x2,x3+w1)(x3w1,[x2,w2])χ(x2+x3,w1)(w1,[x2x3,w2])=χ(x3,w1)χ(x2,w1)(w1,x2[x3,w2])+χ(x2,x3+w1)χ(x3,w1)(w1,x3[x2,w2])χ(x2+x3,w1)(w1,[x2x3,w2])=χ(x2+x3,w1)(w1,x2[x3,w2])+χ(x2+x3,w1)χ(x2,x3)(w1,x3[x2,w2])χ(x2+x3,w1)(w1,[x2x3,w2])=χ(x2+x3,w1)(w1,x2[x3,w2]+χ(x2,x3)x3[x2,w2][x2x3,w2])=χ(x2+x3,w1)(w1,χ(x2+x3,w2)Hw2(x2,x3))=χ(x2+x3,w1+w2)(w1,Hw2(x2,x3)).

    With the above identity, we have

    (Hx1(x2,x3)w1+χ(x1,x2+x3)T(x2,x3)(x1w1)x1T(x2,x3)(w1),w2)=χ(x1+x2+x3,w1)(w1,Hx1(x2,x3)w2)+χ(x1,x2+x3)χ(x2+x3,x1+w1+w2)(x1w1,Hw2(x2,x3))χ(x1,x2+x3+w1)(T(x2,x3)w1,x1w2)=χ(x1+x2+x3,w1)(w1,Hx1(x2,x3)w2)+χ(x1,w1)χ(x2+x3,w1+w2)(w1,x1Hw2(x2,x3))χ(x1,x2+x3+w1)χ(x2+x3,x+w1+w2)(w1,Hx1w2(x2,x3))=χ(x1+x2+x3,w1)(w1,Hx1(x2,x3)w2)+χ(x1,w1)χ(x2+x3,w1+w2)(w1,x1Hw2(x2,x3))χ(x1,w1)χ(x2+x3,w1+w2)(w1,Hx1w2(x2,x3))=χ(x1+x2+x3,w1)(w1,Hx1(x2,x3)w2+χ(x2+x3,w2)x1Hw2(x2,x3)χ(x2+x3,w2)Hx1w2(x2,x3))=χ(x1+x2+x3,w1)(w1,Hx1(x2,x3)w2+χ(x2+x3,w2)x1Hw2(x2,x3)(Hx1(x2,x3)w2+χ(x2+x3,w2)x1Hw2(x2,x3)))=0.

    Then, according to the assumption that the symmetric bilinear form (,) is non-degenerate, the conclusion is obtained.

    The concept of pre-F-manifold color algebras is presented in this section, and using these algebras we construct F-manifold color algebras.

    Definition 4.1. Let the vector space F be G-graded and be a bilinear multiplication operator on F. A triple (F,,χ) is called a Zinbiel color algebra if the following hold:

    (i) Fg1Fg2Fg1+g2,

    (ii) x1(x2x3)=(x1x2)x3+χ(x1,x2)(x2x1)x3,

    for any homogeneous elements x1Fg1,x2Fg2,x3Fg3, and g1,g2,g3G.

    Given a Zinbiel color algebra (F,,χ), define

    x1x2=x1x2+χ(x1,x2)x2x1, (4.1)

    for any homogeneous elements x1,x2F. Then it is not difficult to see that the algebra (F,,χ) is both χ-commutative and associative.

    Define a linear map L:FEndk(F)G by

    Lx1x2=x1x2, (4.2)

    for any homogeneous elements x1,x2F. Then one has the following result.

    Lemma 4.1. With the above notations, (F,L) is a representation of (F,,χ).

    Proof. According to the definition of L, we get

    Lx1x2x3=(x1x2)x3=(x1x2+χ(x1,x2)(x2x1))x3=x1(x2x3)=Lx1Lx2x3.

    Thus, the proof follows.

    Let (F,,χ) be a Zinbiel color algebra and (F,,χ) be a pre-Lie color algebra. For any homogeneous elements x1,x2,x3F, define two linear maps Q1,Q2:FFFF by

    Q1(x1,x2,x3)=x1(x2x3)χ(x1,x2)x2(x1x3)[x1,x2]x3,Q2(x1,x2,x3)=x1(x2x3)+χ(x1,x2)x2(x1x3)(x1x2)x3,

    where the operation is given by (4.1) and the bracket [,] is given by

    [x1,x2]=x1x2χ(x1,x2)x2x1. (4.3)

    Definition 4.2. With the above notations, (F,,,χ) is called a pre-F-manifold color algebra if the following hold

    (Q1(x1,x2,x3)+χ(x2,x3)Q1(x1,x3,x2)+χ(x1,x2+x3)Q2(x2,x3,x1))x4=χ(x1,x2+x3)Q2(x2,x3,x1x4)x1Q2(x2,x3,x4),
    Q1(x1x2,x3,x4)=x1Q1(x2,x3,x4)+χ(x1,x2)x2Q1(x1,x3,x4)

    for any homogeneous elements x1,x2,x3,x4F.

    Since (F,[,],χ) is a Lie color algebra, it is known that (F,L) is a representation of (F,[,],χ) if one defines the linear map L:FEndk(F)G by

    Lx1x2=x1x2, (4.4)

    for any homogeneous elements x1,x2F.

    Theorem 4.2. Suppose that (F,,,χ) is a pre-F-manifold color algebra; then

    (1) (F,,[,],χ) is an F-manifold color algebra, where the operation is given by (4.1) and the bracket [,] is given by (4.3);

    (2) (F;L,L) is a representation of (F,,[,],χ), where the map L is given by (4.4) and the map L is given by (4.2).

    Proof. (1) It is known that (F,[,],χ) is a Lie color algebra and (F,,χ) is a χ-commutative associative algebra. Thus, we only need to prove that the relation in Definition 3.1 is satisfied.

    Assume that x1,x2,x3,x4F are all homogeneous elements. We claim the following identity:

    Hx1(x2,x3)=Q1(x1,x2,x3)+χ(x2,x3)Q1(x1,x3,x2)+χ(x1,x2+x3)Q2(x2,x3,x1). (4.5)

    In fact, we have

    Hx1(x2,x3)=[x1,x2x3][x1,x2]x3χ(x1,x2)x2[x1,x3]=x1(x2x3)χ(x1,x2+x3)(x2x3)x1[x1,x2]x3χ(x+x2,x3)x3[x1,x2]χ(x1,x2){x2[x1,x3]+χ(x2,x1+x3)[x1,x3]x2}=x1(x2x3)χ(x1,x2)x2(x1x3)[x1,x2]x3+χ(x2,x3){x1(x3x2)χ(x1,x3)x3(x1x2)[x1,x3]x2}+χ(x1,x2+x3){x2(x3x1)+χ(x2,x3)x3(x2x1)(x2x3)x1}=Q1(x1,x2,x3)+χ(x2,x3)Q1(x1,x3,x2)+χ(x1,x2+x3)Q2(x2,x3,x1).

    With the above identity, we obtain

    Hx1x2(x3,x4)x1Hx2(x3,x4)χ(x1,x2)x2Hx1(x3,x4)=Q1(x1x2,x3,x4)+χ(x3,x4)Q1(x1x2,x4,x3)+χ(x1+x2,x3+x4)Q2(x3,x4,x1x2)x1{Q1(x2,x3,x4)+χ(x3,x4)Q1(x2,x4,x3)+χ(x2,x3+x4)Q2(x3,x4,x2)}χ(x1,x2)x2{Q1(x1,x3,x4)+χ(x3,x4)Q1(x1,x4,x3)+χ(x1,x3+x4)Q2(x3,x4,x1)}={Q1(x1x2,x3,x4)x1Q1(x2,x3,x4)χ(x1,x2)x2Q1(x1,x3,x4)}+{χ(x3,x4)Q1(x1x2,x4,x3)χ(x3,x4)x1Q1(x2,x4,x3)χ(x1,x2)χ(x3,x4)x2Q1(x1,x4,x3)}+{χ(x1+x2,x3+x4)Q2(x3,x4,x1x2)χ(x1,x2)χ(x2,x1+x3+x4)Q1(x1,x3,x4)x2χ(x1,x2)χ(x3,x4)χ(x2,x1+x3+x4)Q1(x1,x4,x3)x2χ(x1,x2)χ(x1,x3+x4)χ(x2,x1+x3+x4)Q2(x3,x4,x1)x2χ(x2,x3+x4)x1Q2(x3,x4,x2)}+{χ(x1+x2,x3+x4)χ(x1,x2)Q2(x3,x4,x2x1)χ(x1,x2+x3+x4)Q1(x2,x3,x4)x1χ(x3,x4)χ(x1,x2+x3+x4)Q1(x2,x4,x3)x1χ(x2,x3+x4)χ(x1,x3+x4+x2)Q2(x3,x4,x2)x1χ(x1,x2)χ(x1,x3+x4)x2Q2(x3,x4,x1)}=χ(x1+x2,x3+x4){Q2(x3,x4,x1x2)χ(x3+x4,x1)Q1(x1,x3,x4)x2χ(x3,x4)χ(x3+x4,x1)Q1(x1,x4,x3)x2Q2(x3,x4,x1)x2χ(x3+x4,x1)x1Q2(x3,x4,x2)}+χ(x1,x2+x3+x4){χ(x2,x3+x4)Q2(x3,x4,x2x1)Q1(x2,x3,x4)x1χ(x3,x4)Q1(x2,x4,x3)x1χ(x2,x3+x4)Q2(x3,x4,x2)x1x2Q2(x3,x4,x1)}=χ(x2,x3+x4){χ(x1,x3+x4)Q2(x3,x4,x1x2)Q1(x1,x3,x4)x2χ(x3,x4)Q1(x1,x4,x3)x2χ(x1,x3+x4)Q2(x3,x4,x1)x2x1Q2(x3,x4,x2)}=0.

    Hence, (F,,[,],χ) is an F-manifold color algebra.

    (2) It is known that (F,L) is a representation of the Lie color algebra (F,[,],χ). According to Lemma 4.1, (F,L) is a representation of the χ-commutative associative algebra (F,,χ). Define the linear map M4 from FF to Endk(F)G by

    M4(x1,x2)=Lx1Lx2χ(x1,x2)Lx2Lx1L[x1,x2].

    Thus Q1(x1,x2,x3)=M4(x1,x2)(x3), and the equation

    Q1(x1x2,x3,x4)=x1Q1(x2,x3,x4)+χ(x1,x2)x2Q1(x1,x3,x4)

    implies

    M4(x1x2,x3)=Lx1M4(x2,x3)+χ(x1,x2)Lx2M4(x1,x3).

    On the other hand, define the linear map M5 from FF to Endk(F)G by

    M5(x1,x2)=Lx1Lx2+χ(x1,x2)Lx2Lx1Lx1x2.

    Thus Q2(x1,x2,x3)=M5(x1,x2)(x3). Combining (4.5), the equation

    (Q1(x1,x2,x3)+χ(x2,x3)Q1(x1,x3,x2)+χ(x1,x2+x3)Q2(x2,x3,x1))x4=χ(x1,x2+x3)Q2(x2,x3,x1x4)x1Q2(x2,x3,x4)

    implies

    LHx1(x2,x3)=χ(x1,x2+x3)M5(x2,x3)Lx1Lx1M5(x2,x3).

    Hence, the proof is completed.

    An F-manifold is "locally" an F-manifold algebra. We generalize the definition of an F-manifold algebra by introducing an F-manifold color algebra and study its representation theory. Then we provide the concept of a coherence F-manifold color algebra and obtain that an F-manifold color algebra admitting a non-degenerate symmetric bilinear form is a coherence F-manifold color algebra. The concept of a pre-F-manifold color algebra is also defined, and with the help of these algebras, one can construct F-manifold color algebras.

    The authors declare they have not used Artificial Intelligence (AI) tools in the creation of this article.

    This work was supported by the Guangdong Basic and Applied Basic Research Foundation (2023A1515011739) and the Basic Research Joint Funding Project of University and Guangzhou City under Grant 202201020103.

    The authors declare there are no conflicts of interest.



    Author contributions



    Conceptualization, SH; Writing original draft-manuscript, SH; Writing, review, editing, MAR; Figure preparation, SN; Reading and editing, SIJ, AB, and SN.
    All authors have read and agreed to the published version of the manuscript.

    Conflict of interest



    The authors declare no conflict of interest.

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