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Double casting prototyping with a thermal aging step for fabrication of 3D microstructures in poly(dimethylsiloxane)

  • Received: 23 September 2016 Accepted: 16 November 2016 Published: 22 November 2016
  • The paper describes a cheap and accessible technique of a poly(dimethylsiloxane) (PDMS) master treatment by thermal aging as a step of double casting microfabrication process. Three-dimensional PDMS microstructures could have been achieved using this technique. It was proved, that thermal aging changes nanotopology of a PDMS surface and thus enhances efficiency of double casting prototyping. The thermally aged PDMS master could have been used for multiple and correct replication of over 98% of the fabricated microstructures. Moreover, lack of chemical modification preserved the biocompatibility of PDMS devices. The fabricated microstructures were successfully utilized for 3D cell culture.

    Citation: Karina Kwapiszewska, Kamil Żukowski, Radosław Kwapiszewski, Zbigniew Brzózka. Double casting prototyping with a thermal aging step for fabrication of 3D microstructures in poly(dimethylsiloxane)[J]. AIMS Biophysics, 2016, 3(4): 553-562. doi: 10.3934/biophy.2016.4.553

    Related Papers:

  • The paper describes a cheap and accessible technique of a poly(dimethylsiloxane) (PDMS) master treatment by thermal aging as a step of double casting microfabrication process. Three-dimensional PDMS microstructures could have been achieved using this technique. It was proved, that thermal aging changes nanotopology of a PDMS surface and thus enhances efficiency of double casting prototyping. The thermally aged PDMS master could have been used for multiple and correct replication of over 98% of the fabricated microstructures. Moreover, lack of chemical modification preserved the biocompatibility of PDMS devices. The fabricated microstructures were successfully utilized for 3D cell culture.


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