Review

Deep brain stimulation, lesioning, focused ultrasound: update on utility

  • Received: 15 March 2023 Revised: 13 April 2023 Accepted: 23 April 2023 Published: 26 April 2023
  • Procedures for neurological disorders such as Parkinsons Disease (PD), Essential Tremor (ET), Obsessive Compulsive Disorder (OCD), Tourette's Syndrome (TS), and Major Depressive Disorder (MDD) tend to overlap. Common therapeutic procedures include deep brain stimulation (DBS), lesioning, and focused ultrasound (FUS). There has been significant change and innovation regarding targeting mechanisms and new advancements in this field allowing for better clinical outcomes in patients with severe cases of these conditions. In this review, we discuss advancements and recent discoveries regarding these three procedures and how they have led to changes in utilization in certain conditions. We further discuss the advantages and drawbacks of these treatments in certain conditions and the emerging advancements in brain-computer interface (BCI) and its utility as a therapeutic for neurological disorders.

    Citation: Akshay Reddy, Mohammad Reza Hosseini, Aashay Patel, Ramy Sharaf, Vishruth Reddy, Arman Tabarestani, Brandon Lucke-Wold. Deep brain stimulation, lesioning, focused ultrasound: update on utility[J]. AIMS Neuroscience, 2023, 10(2): 87-108. doi: 10.3934/Neuroscience.2023007

    Related Papers:

  • Procedures for neurological disorders such as Parkinsons Disease (PD), Essential Tremor (ET), Obsessive Compulsive Disorder (OCD), Tourette's Syndrome (TS), and Major Depressive Disorder (MDD) tend to overlap. Common therapeutic procedures include deep brain stimulation (DBS), lesioning, and focused ultrasound (FUS). There has been significant change and innovation regarding targeting mechanisms and new advancements in this field allowing for better clinical outcomes in patients with severe cases of these conditions. In this review, we discuss advancements and recent discoveries regarding these three procedures and how they have led to changes in utilization in certain conditions. We further discuss the advantages and drawbacks of these treatments in certain conditions and the emerging advancements in brain-computer interface (BCI) and its utility as a therapeutic for neurological disorders.



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    The authors declare no conflict of interest.

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