Mini review Topical Sections

The essential measures to improve the management of anaphylaxis

  • Received: 03 August 2020 Accepted: 02 November 2020 Published: 04 November 2020
  • Studies of anaphylaxis in humans is scarce. It has been proven that the frequency of anaphylactic reactions is in increase and its management is not adequate and/or below an acceptable level. The prescription of auto-injectable epinephrine for use outside the hospital, which is the treatment of choice for an anaphylactic reaction, and its correct administration is drastically low. The proper management of anaphylaxis involves improving the training of patient's behaviors to allow both (i) prevention (avoiding known triggers of anaphylaxis) and (ii) effective treatment (adherence to a self-care plan and training to apply epinephrine with an auto-injector). Therefore, it is necessary to ensure and monitor the correct prescription of adrenaline auto-injectors as well as the training of health professionals in such use.

    Citation: Fernando-Miguel Gamboa-Antiñolo. The essential measures to improve the management of anaphylaxis[J]. AIMS Medical Science, 2020, 7(4): 293-297. doi: 10.3934/medsci.2020018

    Related Papers:

  • Studies of anaphylaxis in humans is scarce. It has been proven that the frequency of anaphylactic reactions is in increase and its management is not adequate and/or below an acceptable level. The prescription of auto-injectable epinephrine for use outside the hospital, which is the treatment of choice for an anaphylactic reaction, and its correct administration is drastically low. The proper management of anaphylaxis involves improving the training of patient's behaviors to allow both (i) prevention (avoiding known triggers of anaphylaxis) and (ii) effective treatment (adherence to a self-care plan and training to apply epinephrine with an auto-injector). Therefore, it is necessary to ensure and monitor the correct prescription of adrenaline auto-injectors as well as the training of health professionals in such use.


    加载中


    Conflicts of interest



    The author declares there is no conflicts of interest.

    [1] Golden DBK (2017) Anaphylaxis: recognizing risk and targeting treatment. J Allergy Clin Immunol Pract 5: 1224-1226. doi: 10.1016/j.jaip.2017.06.028
    [2] Sienra-Monge JL, Navarrete-Rodriguez EM, Chavez-Flores U, et al. (2019) Anaphylaxis in children and adults: prevention, diagnosis and treatment. Rev Conamed 24: 107-164. [Article in Spanish].
    [3] Alvarez-Perea A, Ameiro B, Morales C, et al. (2017) Anaphylaxis in the pediatric emergency department: analysis of 133 cases after an allergy workup. J Allergy Clin Immunol Pract 5: 1256-1263. doi: 10.1016/j.jaip.2017.02.011
    [4] Wood RA, Camargo CA, Lieberman P, et al. (2014) Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States. J Allergy Clin Imunol 133: 461-467. doi: 10.1016/j.jaci.2013.08.016
    [5] Ma L, Danoff TM, Borish L (2014) Case fatality and population mortality associated with anaphylaxis in the United States. J Allergy Clin Immunol 133: 1075-1083. doi: 10.1016/j.jaci.2013.10.029
    [6] Turner PJ, Jerschow E, Umasunthar T, et al. (2017) Fatal anaphylaxis: mortality rate and risk factors. J Allergy Clin Immunol Pract 5: 1169-1178. doi: 10.1016/j.jaip.2017.06.031
    [7] Greenberger P, Rotskoff BD, Lifschvitz B (2007) Fatal anaphylaxis: post-mortem findings and associated comorbid diseases. Ann Allergy Asthma Immunol 98: 252-257. doi: 10.1016/S1081-1206(10)60714-4
    [8] Pumphrey RS (2004) Fatal anaphylaxis in the UK: 1992–2001. Novartis Found Symp 257: 116-128.
    [9] Yunginger JW, Nelson DR, Squillace DL, et al. (1991) Laboratory investigation of deaths due to anaphylaxis. J Forensic Sci 36: 857-865. doi: 10.1520/JFS13095J
    [10] Pumphrey RS (2000) Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy 30: 1144-1150. doi: 10.1046/j.1365-2222.2000.00864.x
    [11] Campbell RL, Li JTC, Nicklas RA, et al. (2014) Emergency department diagnosis and treatment of anaphylaxis: a practice parameter. Ann Allergy Asthma Immunol 113: 599-608. doi: 10.1016/j.anai.2014.10.007
    [12] Bonds RS, Asawa A, Ghazi AI (2015) Misuse of medical devices: a persistent problem in self-management of asthma and allergic disease. Ann Allergy Asthma Immunol 114: 74-76. doi: 10.1016/j.anai.2014.10.016
    [13] Ridolo E, Montagni M, Bonzano L, et al. (2015) How far from correct is the use of adrenaline auto-injectors? A survey in Italian patients. Intern Emerg Med 10: 937-941. doi: 10.1007/s11739-015-1255-z
    [14] Ewan P, Braithwaite N, Leech S, et al. (2016) BSACI guideline: prescribing an adrenaline auto-injector. Clin Exp Allergy 46: 1258-1280. doi: 10.1111/cea.12788
    [15] Mehr S, Robinson M, Tang M (2007) Doctor—How do I use my EpiPen? Pediatr Allergy Immunol 18: 448-452. doi: 10.1111/j.1399-3038.2007.00529.x
    [16] Saleh-Vandenberg J, deVries S, Bak E, et al. (2017) Incomplete and incorrect epinephrine auto-injector training to food allergic patients by pharmacists in the Netherlands. Pediatr Allergy Immunol 28: 238-244. doi: 10.1111/pai.12688
    [17] Salter SM, Loh R, Sanfilippo F, et al. (2014) Demonstration of epinephrine autoinjectors (EpiPen and Anapen) by pharmacists in a randomised, simulated patient assessment: acceptable, but room for improvement. Allergy Asthma Clin Immunol 10: 49. doi: 10.1186/1710-1492-10-49
    [18] Mahoney B, Walklet E, Bradley E, et al. (2019) Improving adrenaline autoinjector adherence: a psychologically informed training for healthcare professionals. Immun Inflamm Dis 7: 214-228. doi: 10.1002/iid3.264
    [19] Antiñolo FMG (2015) How incorrect is the use of adrenaline auto-injectors? Intern Emerg Med 10: 887-888. doi: 10.1007/s11739-015-1290-9
    [20] Waserman S, Avilla E, Ben-Shoshan M, et al. (2017) Epinephrine autoinjectors: new data, new problems. J Allergy Clin Immunol Pract 5: 1180-1191. doi: 10.1016/j.jaip.2017.06.027
    [21] Brown AFT (2009) Current management of anaphylaxis. Emergencias 21: 213-223.
    [22] García-Magán C, Montero JMG, Moure-González JD, et al. (2020) Rapid and safe use of adrenaline auto-injectors: We have a problem!. An Pediatr (Barc) 92: 388-389. [Article in Spanish]. doi: 10.1016/j.anpedi.2019.11.006
  • Reader Comments
  • © 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(2236) PDF downloads(97) Cited by(0)

Article outline

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog