Sorghum as a renewable feedstock for production of fuels and industrial chemicals

Nhuan P. Nghiem; Justin Montanti; David B. Johnston; Nhuan P. Nghiem; Justin Montanti; David B. Johnston

doi:10.3934/bioeng.2016.1.75

AIMS Bioengineering

2016, Volume 3, Issue 1: 75-91. doi: 10.3934/bioeng.2016.1.75

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Review

Sorghum as a renewable feedstock for production of fuels and industrial chemicals

Eastern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, Wyndmoor, Pennsylvania, 19038 USA

Received: 24 September 2015 Accepted: 07 January 2016 Published: 13 January 2016

Considerable efforts have been made in the USA and other countries to develop renewable feedstocks for production of fuels and chemicals. Among these, sorghum has attracted strong interest because of its many good characteristics such as rapid growth and high sugar accumulation, high biomass production potential, excellent nitrogen usage efficiency, wide adaptability, drought resistance, and water lodging tolerance and salinity resistance. The ability to withstand severe drought conditions and its high water usage efficiency make sorghum a good renewable feedstock suitable for cultivation in arid regions, such as the southern US and many areas in Africa and Asia. Sorghum varieties include grain sorghum, sweet sorghum, and biomass sorghum. Grain sorghum, having starch content equivalent to corn, has been considered as a feedstock for ethanol production. Its tannin content, however, may cause problems during enzyme hydrolysis. Sweet sorghum juice contains sucrose, glucose and fructose, which are readily fermentable by Saccharomyces cerevisiae and hence is a good substrate for ethanol fermentation. The enzyme invertase, however, needs to be added to convert sucrose to glucose and fructose if the juice is used for production of industrial chemicals in fermentation processes that employ microorganisms incapable of metabolizing sucrose. Biomass sorghum requires pretreatment prior to enzymatic hydrolysis to generate fermentable sugars to be used in the subsequent fermentation process. This report reviews the current knowledge on bioconversion of sorghum to fuels and chemicals and identifies areas that deserve further studies.
- Sorghum,
- renewable feedstocks,
- ethanol,
- industrial chemicals,
- biorefinery.
Citation: Nhuan P. Nghiem, Justin Montanti, David B. Johnston. Sorghum as a renewable feedstock for production of fuels and industrial chemicals[J]. AIMS Bioengineering, 2016, 3(1): 75-91. doi: 10.3934/bioeng.2016.1.75

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Abstract

Considerable efforts have been made in the USA and other countries to develop renewable feedstocks for production of fuels and chemicals. Among these, sorghum has attracted strong interest because of its many good characteristics such as rapid growth and high sugar accumulation, high biomass production potential, excellent nitrogen usage efficiency, wide adaptability, drought resistance, and water lodging tolerance and salinity resistance. The ability to withstand severe drought conditions and its high water usage efficiency make sorghum a good renewable feedstock suitable for cultivation in arid regions, such as the southern US and many areas in Africa and Asia. Sorghum varieties include grain sorghum, sweet sorghum, and biomass sorghum. Grain sorghum, having starch content equivalent to corn, has been considered as a feedstock for ethanol production. Its tannin content, however, may cause problems during enzyme hydrolysis. Sweet sorghum juice contains sucrose, glucose and fructose, which are readily fermentable by Saccharomyces cerevisiae and hence is a good substrate for ethanol fermentation. The enzyme invertase, however, needs to be added to convert sucrose to glucose and fructose if the juice is used for production of industrial chemicals in fermentation processes that employ microorganisms incapable of metabolizing sucrose. Biomass sorghum requires pretreatment prior to enzymatic hydrolysis to generate fermentable sugars to be used in the subsequent fermentation process. This report reviews the current knowledge on bioconversion of sorghum to fuels and chemicals and identifies areas that deserve further studies.

References

[1]	Dale E and Holtzapple M (2015) The needs for biofuels. Chem Eng Prog 111: 36–44.
[2]	2014 World Fuel Ethanol Production, Renewable Fuels Association (RFA) (2014) Available from: http://ethanolrfa.org/pages/World-Fuel-Ethanol-Production.
[3]	Connor M, Liao J (2009) Microbial production of advanced transportation fuels in non-natural hosts. Curr Opin Biotechnol 20: 307–315. doi: 10.1016/j.copbio.2009.04.002
[4]	Kumar M, Gayen K (2011) Development in biobutanol production: New insights. Appl Energy 88: 1999–2012. doi: 10.1016/j.apenergy.2010.12.055
[5]	Ni Y, Sun Z (2009) Recent progress in industrial fermentative production of acetone-butanol-ethanol by Clostridium acetobutylicum in China. Appl Microbiol Biotechnol 83: 415–423. doi: 10.1007/s00253-009-2003-y
[6]	Mattam A, Yazdani S (2013) Engineering E. coli strain for conversion of short chain fatty acids to bioalcohols. Biotechnol Biofuel 6: 128.
[7]	Werpy T, Petersen G (2004) Top Value Added Chemicals from Biomass, Volume 1 – Results of screening for potential candidates from sugars and synthesis gas. U. S. Department of Energy.
[8]	Nghiem N, Donnelly M, Millard C, et al. (1999) Method for the production of dicarboxylic acids, U. S. Patent 5,869,301.
[9]	Donnelly M, Sanville-Millard C, Nghiem N (2004) Method to produce succinic acid from raw hydrolysates. U. S. Patent 6,743,610.
[10]	Nghiem N, Davison B, Donnelly M, et al. (2001) An integrated process for the production of chemicals from biologically derived succinic acid. In: J.J. Bozell (Ed), Chemicals and Materials from Renewable Resources, ACS Symposium Series 784, Washington: American Chemical Society, 160–173.
[11]	De Guzman D (2014) More bio-succinic acid commercialization milestones. Green Chemicals Blog. Available from: http://greenchemicalsblog.com/2014/10/07/more-bio-succinic-acid-commercialization-milestones/.
[12]	Almodares A, Sepahi A (1996) Comparison among sweet sorghum cultivars, lines and hybrids for sugar production. Ann Plant Physiol 10: 50–55.
[13]	Almodares A, Sepahi A, Dalilitajary H, et al. (1994) Effect of phonological stages on biomass and carbohydrate contents of sweet sorghum cultivars. Ann Plant Physiol 8: 42–48.
[14]	Bean B, Bronson K, Schwartz R, et al. (2008) Nitrogen requirements of sorghums for biofuel feedstock production in the southern high plains. Proc Great Plains Soil Fertility Conf, Denver, CO, 15–18.
[15]	Reddy B, Ramesh S, Reddy P, et al. (2005) Sweet sorghum—A potential alternate raw material for bio-ethanol and bio-energy. Int Sorghum Millets Newslett 46: 79–86.
[16]	Tesso T, Claflin L, Tuinstra M (2005) Analysis of stalk rot resistance and genetic diversity among drought tolerant sorghum genotypes. Crop Sci 45: 645–652. doi: 10.2135/cropsci2005.0645
[17]	Vasilakoglou I, Dhima K, Karagiannidis N, et al. (2011) Sweet sorghum productivity for biofuels under increased soil salinity and reduced irrigation. Field Crops Res 120: 38–46.
[18]	Shoemaker C, Bransby D (2010) The role of sorghum as a bioenergy feedstock. Proc Sustainable Feedstocks for Advance Biofuels Workshop, Atlanta, GA, 149–159.
[19]	Almodares A, Hadi M (2009) Production of bioethanol from sweet sorghum: A review. African J Ag Res 4: 772–780.
[20]	Ratnavathi C, Chakravarthy S, Komala V, et al. (2011) Sweet sorghum as feedstock for biofuel production: A review. Sugar Tech 13: 399–407. doi: 10.1007/s12355-011-0112-2
[21]	Serna-Saldivar S, Chuck-Hernandez C, Perez-Carrillo E, et al. (2012) Sorghum as a multifunctional crop for the production of fuel ethanol: Current status and future trends. In: M.A.P. Lima (Ed), Bioethanol, Rijeka, Croatia, 51–74.
[22]	Whitfield M, Chinn M, Veal M (2012) Processing of materials derived from sweet sorghum for biobased products. Ind Crops Products 37: 362–375. doi: 10.1016/j.indcrop.2011.12.011
[23]	Eggleston G, Cole M, Andrzejewski B (2013) New commercially viable processing technologies for the production of sugar feedstocks from sweet sorghum (Sorghum bicolor L. Moench) for manufacture of biofuels and bioproducts. Sugar Tech 15: 232–249.
[24]	Wu X, Zhao R, Bean S, et al. (2007) Factors impacting ethanol production from grain sorghum in the dry-grind process. Cereal Chem 84: 130–136. doi: 10.1094/CCHEM-84-2-0130
[25]	2014 Annual Report, United Sorghum Checkoff Program. (2015) Available from: http://sorghumcheckoff.com/wp-content/uploads/2015/02/2015_AnnualReportFinaSM.pdf.
[26]	2015 Ethanol Industry Outlook, Renewable Fuels Association. (2015) Available from: http://ethanolrfa.3cdn.net/c5088b8e8e6b427bb3_cwm626ws2.pdf.
[27]	Wang D, Bean S, McLaren J, et al. (2008) Grain sorghum is a viable feedstock for ethanol production. J Ind Microbiol Biotechnol 35: 313–320. doi: 10.1007/s10295-008-0313-1
[28]	Zhao R, Bean S, Wang D, et al. (2009) Small-scale mashing procedure for predicting ethanol yield of sorghum grain. J Cereal Sci 49: 230–238. doi: 10.1016/j.jcs.2008.10.006
[29]	Butler L, Riedl D, Lebryk D, et al. (1984) Interaction of proteins with sorghum tannin: Mechanism, specificity and significance. J Am Oil Chem Soc 61: 916–920. doi: 10.1007/BF02542166
[30]	Corredor D, Bean S, Schober T, et al. (2006) Effect of decorticating sorghum on ethanol production and composition of DDGS. Cereal Chem 83: 17–21. doi: 10.1094/CC-83-0017
[31]	Awika J, McDonough C, Rooney L (2005) Decorticating sorghum to concentrate healthy phytochemicals.J Agric Food Chem53: 6230–6234.
[32]	Reichert R, Fleming S, Schwab D (1980) Tannin deactivation and nutritional improvement of sorghum by anaerobic storage of H₂O-, HCl-, or NaOH-treated grain. J Agric Food Chem 28: 824–829. doi: 10.1021/jf60230a045
[33]	Chavan J, Kadam S, Ghonsikar C, et al. (1979) Removal of tannins and improvement of in vitro protein digestibility of sorghum seeds by soaking in alkali. J Food Sci 44: 1319–1322. doi: 10.1111/j.1365-2621.1979.tb06429.x
[34]	Zhan X, Wang D, Sun X, et al. (2003) Lactic acid production using extrusion-cooked grain sorghum. Trans ASAE 46: 589–593.
[35]	Fang Q, Hanna M (2002) Experimental studies for levulinic acid production from whole kernel grain sorghum. Bioresource Technol 81: 187–192. doi: 10.1016/S0960-8524(01)00144-4
[36]	Wang Y, Tilley M, Bean S, et al. (2009) Comparison of methods for extracting kafirin proteins from sorghum distillers dried grains with solubles. J Agric Food Chem 57: 8366–8372.
[37]	Reddy B, Ramesh S, Reddy P, et al. (2005) Sweet sorghum—a potential alternate raw material for bio-ethanol and bioenergy. Int Sorghum Millets Newsletter 46: 79–86.
[38]	Guigou M, Lareo C, Perez L, et al. (2011) Bioethanol production from sweet sorghum: Evaluation of post-harvest treatments on sugar extraction and fermentation. Biomass Bioenerg 35: 3058–3062. doi: 10.1016/j.biombioe.2011.04.028
[39]	Wu X, Staggenborg S, Propheter J, et al. (2010) Features of sweet sorghum juice and their performance in ethanol fermentation. Ind Crops Products 3: 164–170.
[40]	Mamma D, Christakopoulos P, Koullas D, et al. (1995) An alternative approach to the bioconversion of sweet sorghum carbohydrates to ethanol. Biomass Bioenerg 8: 99–103. doi: 10.1016/0961-9534(95)00006-S
[41]	Reddy B, Ramesh S, Reddy P, et al. (2005) Sweet sorghum—A potential alternate raw material for bio-ethanol and bio-energy. Int Sorghum Millets Newslett 46: 79–86.
[42]	Laopaiboon L, Thanonkeo P, Jaisil P, et al. (2007) Ethanol production from sweet sorghum juice in batch and fed-batch fermentations by Saccharomyces cerevisiae. World J Microbiol Biotechnol 23: 1497–1501. doi: 10.1007/s11274-007-9383-x
[43]	Laopaiboon L, Nuanpeng S, Srinophakun P, et al. (2009) Ethanol production from sweet sorghum juice using very high gravity technology: Effects of carbon and nitrogen supplementations. Bioresource Technol 100: 4176–4182. doi: 10.1016/j.biortech.2009.03.046
[44]	Worley J, Vaughan D, Cundiff J (1992) Energy analysis of ethanol production from sweet sorghum, Bioresource Technol 40: 263–273.
[45]	Mei X, Liu R, Shen F and Wu H (2009) Optimization of fermentation conditions for the production of ethanol from stalk juice of sweet sorghum by immobilized yeast using response surface methodology. Energy and Fuels 23: 487–491. doi: 10.1021/ef800429u
[46]	Yu J, Zhang X, Tan T (2009) Optimization of media conditions for the production of ethanol from sweet sorghum juice by immobilized Saccharomyces cerevisiae. Biomass Bioenerg 33: 521–526.
[47]	Gnansounou E, Dauriat A, Wyman C (2005) Refining sweet sorghum to ethanol and sugar: economic trade-offs in the context of North China. Bioresource Technol 96: 985–1002. doi: 10.1016/j.biortech.2004.09.015
[48]	Wang F, Liu C (2009) Development of an economic refining strategy of sweet sorghum in the Inner Mongolia region of China. Energy & Fuels 23: 4137–4142.
[49]	Zhang C, Xie G, Li S, et al. (2010) The productive potentials of sweet sorghum in China, Appl Energ 87: 2360–2368.
[50]	Krishnakumar J, Drapcho C, Nghiem N (2014) Biological production of succinic acidusing cull peach medium: Effects of corn steep liquor supplement and hydrogen sparging. Biol Eng Trans 6: 189–202.
[51]	Liu R, Li J, Shen F (2008) Refining bioethanol from stalk juice of sweet sorghum by immobilized yeast fermentation. Renew Energ 33: 1130–1135.
[52]	Hoyer K, Gable M, Zacchi G (2009) Production of fuel ethanol from softwood by simultaneous saccharification and fermentation at high dry matter content. J Chem Technol Biotechnol 84: 570–577. doi: 10.1002/jctb.2082
[53]	Nghiem N, Johnston D, Montanti J (2013) Sweet sorghum biorefinery. Sweet Sorghum Ethanol Association Annual Conference, Orlando, Florida.
[54]	Bennet A, Anex R (2009) Production, transportation and milling costs of sweet sorghum as a feedstock for centralized bioethanol production in the upper Midwest. Bioresource Technol 100: 1595–1607.
[55]	Linton J, Miller J, Little R, et al. (2011) Economic feasibility of producing sweet sorghum as an ethanol feedstock in the southeastern United States. Biomass Bioenerg 35: 3050–3057. doi: 10.1016/j.biombioe.2011.04.007
[56]	Munyinda K, Yamba F (2007) Sweet sorghum as a complementary bioethanol feedstock – From southern Africa perspective. Workshop on Biofuels: R&D and Technologies for a Sustainable Development in Africa, Accra, Ghana.
[57]	Prasad S, Singh A, Jain N, et al. (2007) Ethanol production from sweet sorghum syrup for utilization as automotive fuel in India. Energ Fuel 21: 2415–2420. doi: 10.1021/ef060328z
[58]	Lixin Z (2008) Life cycle assessment on biofuel derived from sweet sorghum. International Conference on Sorghum for Biofuel, Houston, TX.
[59]	Hetényi K, Nemeth A, Sevella B (2010) Use of sweet sorghum juice for lactic acid fermentation: preliminary steps in a process optimization. J Chem Technol Biotechnol 85: 872–877. doi: 10.1002/jctb.2381
[60]	Liang Y, Sarkany N, Cui Y, et al. (2010) Use of sweet sorghum juice for lipid production by Schizochytrium limacinum SR21. Bioresource Technol 101: 3623–3627.
[61]	Tanamool V, Kaewkannetra P, Danvirutai P, et al. (2009) Production of poly-β-hydroxybutyric acid (PHB) from sweet sorghum juice by Alcaligenes eutrophus TISTR 1095 and Alcaligenes latus ATCC 29724 via batch fermentation, 3^rd International Conference on Fermentation Technology for Value Added Agricultural Products, Khon Kaen, Thailand.
[62]	Areesirisuk A, Laopaiboon L, Khongsay N, et al. (2010) Improvement of gas chromatographic analysis for organic acids and organic solvents in acetone-butanol-ethanol fermentation from sweet sorghum juice. African J Biotechnol 9: 6422–6429.
[63]	Espinola W (2010) Butanol from sweet sorghum juice by Clostridium beijerinckii SA1/ATCC 35702, MS Thesis, North Carolina State University, Raleigh, North Carolina.
[64]	Claassen P, de Vrije T, Budde M (2004) Biological hydrogen production from sweet sorghum by thermophilic bacteria, 2^nd World Conference on Biomass for Energy, Industrial and Climate Protection, Rome, Italy.
[65]	Nghiem N, Johnston D, Moreau R, et al. (2014) Potential use of sweet sorghum juice and bagasse as feedstocks for production of industrial chemicals. Sweet Sorghum Ethanol Association Annual Conference, Orlando, Florida.
[66]	Voegel E (2015) Report highlights growth of biofuel production in China. Ethanol Producer Magazine. Available from: http://ethanolproducer.com/articles/11859/report-highlights-growth-of-biofuel-production-in-china.
[67]	Rooney W, Blumenthal J, Bean B, et al. (2007) Designing sorghum as a bioenergy feedstock, Biofuel Bioprod Bior 1: 147–157.
[68]	U.S. Department of Energy. Biomass feedstock composition and property database, Biomass Program. Available from: http://www.afdc.energy.gov/biomass/progs/search2.cgi?8387.
[69]	Drapcho C, Nghiem N, Walker T (2008) Biofuels Engineering Process Technology, Mc-Graw-Hill, New York, 105–195.
[70]	Sipos B, Reczey J, Somorai Z, et al. (2009) Sweet sorghum as feedstock for ethanol production: Enzymatic hydrolysis of steam-pretreated bagasse. Appl Biochem Biotechnol 153:151–162. doi: 10.1007/s12010-008-8423-9
[71]	Li B, Balan V, Yuan Y, et al. (2010) Process optimization to convert forage and sweet sorghum bagasse to ethanol based on ammonia fiber expansion (AFEX) pretreatment. Bioresource Technol 101: 1285–1292. doi: 10.1016/j.biortech.2009.09.044
[72]	Ban J, Yu J, Zhang X, et al. (2008) Ethanol production from sweet sorghum residual. Front Chem Eng China 2: 452–455.
[73]	Cao W, Sun C, Liu R, et al. (2012) Comparison of the effects of five pretreatment methods on enhancing the enzymatic digestibility and ethanol production from sweet sorghum bagasse. Bioresource Technol 111: 215–221. doi: 10.1016/j.biortech.2012.02.034
[74]	Dien B, Sarath G, Pedersen J, et al. (2009) Improved sugar conversion and ethanol yield for forage sorghum (Sorghum bicolor L. Moench) lines with reduced lignin contents. Bioenerg Res 2: 153–164.
[75]	Nghiem N, Kim T, Yoo C, et al. (2013) Enzymatic fractionation of SAA-pretreated barley straw for production of fuel ethanol and astaxanthin as a value-added co-product. Appl Biochem Biotechnol 171: 341–351. doi: 10.1007/s12010-013-0374-0
[76]	du Preez J, de Jong F, Botes P and Lategan P (1985) Fermentation alcohol from grain sorghum starch. Biomass 8: 101–117. doi: 10.1016/0144-4565(85)90021-6
[77]	Davila-Gomez F, Chuck-Hernandez C, Perez-Carrillo E, et al. (2011) Evaluation of bioethanol production from five different varieties of sweet and forage sorghums (Sorghum bicolor (L) Moench). Ind Crops Prod 33: 611–616. doi: 10.1016/j.indcrop.2010.12.022
[78]	Camargo D, Sene L, Variz D, et al. (2015) Xylitol bioproduction in hemicellulosic hydrolysate obtained from forage sorghum biomass. Appl Biochem Biotechnol 175: 3628–3642. doi: 10.1007/s12010-015-1531-4
[79]	Nghiem N, Nguyen C, Drapcho C, et al. (2013) Sweet sorghum biorefinery for production of fuel ethanol and value-added co-products. Biol Eng Trans 6: 143–155.
[80]	Dong Q, Zhao X (2004) In situ carbon dioxide fixation in the process of natural astaxanthin production by a mixed culture of Haematococcus pluvialis and Phaffia rhodozyma. Catalysis Today 98: 537–544. doi: 10.1016/j.cattod.2004.09.052
[81]	Nghiem N, Hicks K, Johnston D (2010) Integration of succinic acid and ethanol production with potential application in a corn or barley biorefinery. Appl Biochem Biotechnol 162: 1915–1928. doi: 10.1007/s12010-010-8969-1
[82]	Nsimba R, Mullen C, West N, et al. (2013) Structure-property characteristics of pyrolytic lignins derived from fast pyrolysis of a lignin rich biomass extract. ACS Sustainable Chem Eng 1: 260–267. doi: 10.1021/sc300119s

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