Gut Microbiota and Human Health

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Guest Editors
Prof. David M Segal
College of Health Sciences, Walden University, 100 Washington Avenue South, Minneapolis, MN 55401, USA
Email: David.Segal@mail.waldenu.edu

Prof. Michael Ludwig
Biomedical Sciences, Keiser University, 5600 Lake Underhill Road, Orlando, FL 32807, USA
Email: MiLudwig@keiseruniversity.edu

Manuscript Topics
The human gut is colonized by microbes which outnumber the cells in the human body. While the biodiversity of these microbial strains is limited to a few phyla, recent studies have identified taxonomic differences in the types and abundance of species and strains which allows for the generation of unique microbiome signatures for each individual.

The gut microbiota acts as a metabolic organ that interacts with the host immune system conferring a natural resistance to pathogenic colonization allowing selection of functionally specialized microbial cells which help promote intestinal homeostasis. Perturbations in the gut microbiota composition or dysbiosis has been linked to human diseases in the gut and several other organ systems. High throughput metagenomics can be used to generate genomic profiles of the gut microbiota which may lead to the identification of new biomarkers and therapeutic targets for human disease.

This special issue welcomes contributions related to this topic with established and updated studies about the following areas :

• Molecular and Immunological mechanisms involved with gut microbiota and host interactions
• Genomic characterization of gut microbiota colonization composition
• Recent developments for studying dysbiotic events in gut microbiota
• Molecular fingerprinting of gut microbiota signatures as biomarkers of gut and human disease
• Therapeutic approaches for restoring and maintaining healthy gut microbiota homeostasis

Paper submission
All manuscripts will be peer-reviewed before their acceptance for publication.
The deadline for manuscript submission is February 28, 2019.

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Paola Brun
+ Abstract     + HTML     + PDF(235 KB)
Constance J. Jeffery
+ Abstract     + HTML     + PDF(197 KB)
Lucía Guadamuro, M. Andrea Azcárate-Peril, Rafael Tojo, Baltasar Mayo, Susana Delgado
AIMS Microbiology, 2019, 5(1): 102-116. doi: 10.3934/microbiol.2019.1.102
+ Abstract     + HTML     + PDF(359 KB)
Marina Santiago, Lindsay Eysenbach, Jessica Allegretti, Olga Aroniadis, Lawrence J. Brandt, Monika Fischer, Ari Grinspan, Colleen Kelly, Casey Morrow, Martin Rodriguez, Majdi Osman, Zain Kassam, Mark B. Smith, Sonia Timberlake
+ Abstract     + HTML     + PDF(931 KB)
Ellie Sayers, Alex MacGregor, Simon R. Carding
AIMS Microbiology, 2018, 4(4): 642-654. doi: 10.3934/microbiol.2018.4.642
+ Abstract     + HTML     + PDF(662 KB)
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