What hypotheses can be supported as alternatives (or parallels) to synaptic plasticity as substrates for learning and consolidation of memory in the brain?

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Aims Neuroscience is requesting paper submissions for our November issue. Manuscripts will need to be received by January 28, 2015, and decisions on acceptance will be completed by February 28. While research indicates synaptic plasticity is often correlated with acquisition and/or consolidation of new learning and that treatments that interfere with or enhance plasticity interfere with or enhance memory, similar conditions are met by other neural mechanisms not necessarily occurring at synapses, for example alteration of intrinsic excitability of neurons. Problems with synaptic plasticity mechanisms, including odd time courses of events or dissociation from behavioral outcomes, have been explained away via the notion of sparse coding, although experimental evidence for such hidden plasticity is inherently difficult to obtain. Is it time for our field to entertain alternate hypotheses, based upon available experimental data?

Guest Editor
Dr. Joseph V. Martin
Rutgers State Univ, Ctr Computat & Integrat Biol, 315 Penn St, Camden, NJ 08102 USA.
Email: joe.martin@rutgers.edu

Paper submission
All manuscripts will be peer-reviewed before their acceptance for publication.
The deadline for manuscript submission is 28 January 2015.

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