Biological computing with diffusion and excitable calcium stores

  • Received: 01 February 2004 Accepted: 29 June 2018 Published: 01 March 2004
  • MSC : 92C05, 92C55.

  • Intracellular signaling often employs excitable stores of calcium coupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gates for computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors for biological signals.

    Citation: H. G. E. Hentschel, Alan Fine, C. S. Pencea. Biological computing with diffusion and excitable calcium stores[J]. Mathematical Biosciences and Engineering, 2004, 1(1): 147-159. doi: 10.3934/mbe.2004.1.147

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  • Intracellular signaling often employs excitable stores of calcium coupled by diffusion. We investigate the ability of various geometric configurations of such excitable stores to generate a complete set of logic gates for computation. We also describe how the mechanism of excitable calcium-induced calcium release can be used for constructing coincidence detectors for biological signals.


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  • © 2004 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
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