References: 

• 1. Cryan JF, Dinan TG (2012) Mind-altering microorganisms: The impact of the gut microbiota on brain and behaviour. Nat Rev Neurosci 13: 701–712.    
• 2. Borre YE, Moloney RD, Clarke G, et al. (2014) The impact of microbiota on brain and behavior: Mechanisms & therapeutic potential. Adv Exp Med Biol 817: 373–403.    
• 3. Diagnostic and Statistical Manual of Mental Disorders (DSM-V), 2013. American Psychiatric Association, 189: 4189.
• 4. Siniscalco D, Cirillo A, Bradstreet JJ, et al. (2013) Epigenetic findings in autism: New perspectives for therapy. Int J Environ Res Public Health 10: 4261–4273.    
• 5. Frye RE, Slattery J, Macfabe DF, et al. (2015) Approaches to studying and manipulating the enteric microbiome to improve autism symptoms. Microb Ecol Health Dis 26: 26878.
• 6. De Magistris L, Picardi A, Siniscalco D, et al. (2013) Antibodies against food antigens in patients with autistic spectrum disorders. BioMed Res Int 2013: 729349.
• 7. Mcelhanon BO, Mccracken C, Karpen S, et al. (2014) Gastrointestinal symptoms in autism spectrum disorder: A meta-analysis. Pediatrics 133: 872–883.    
• 8. Adams JB, Johansen LJ, Powell LD, et al. (2011) Gastrointestinal flora and gastrointestinal status in children with autism-comparisons to typical children and correlation with autism severity. BMC Gastroenterol 11: 22.    
• 9. Nikolov RN, Bearss KE, Lettinga J, et al. (2009) Gastrointestinal symptoms in a sample of children with pervasive developmental disorders. J Autism Dev Disord 39: 405–413.    
• 10. Iovene MR, Bombace F, Maresca R, et al. (2017) Intestinal dysbiosis and Yeast Isolation in Stool of Subjects with Autism Spectrum Disorders. Mycopathologia 182: 349–363.    
• 11. Siniscalco D (2014) Gut bacteria-brain axis in autism. Autism 4: e124.
• 12. Kranich J, Maslowski KM, Mackay CR (2011) Commensal flora and the regulation of inflammatory and autoimmune responses. Semin Immunol 23: 139–145.    
• 13. Macfarlane S, Macfarlane GT (2006) Composition and metabolic activities of bacterial biofilms colonizing food residues in the human gut. Appl Environ Microbiol 72: 6204–6211.    
• 14. Liu Y, Fatheree NY, Mangalat N, et al. (2010) Human-derived probiotic Lactobacillus reuteri strains differentially reduce intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 299: G1087–G1096.    
• 15. Fateh R, Iravani S, Frootan M, et al. (2011) Synbiotic preparation in men suffering from functional constipation: A randomised controlled trial. Swiss Med Wkly 141: w13239.
• 16. Vuong HE, Hsiao EY (2017) Emerging Roles for the Gut Microbiome in Autism Spectrum Disorder. Biol Psychiatry 81: 411–423.    
• 17. Strati F, Cavalieri D, Albanese D, et al. (2017) New evidences on the altered gut microbiota in autism spectrum disorders. Microbiome 5: 24.    
• 18. Finegold SM, Molitoris D, Song Y, et al. (2002) Gastrointestinal microflora studies in late-onset autism. Clin Infect Dis 35: S6–S16.    
• 19. Wang L, Christophersen CT, Sorich MJ, et al. (2013) Increased abundance of Sutterella spp. and Ruminococcus torques in feces of children with autism spectrum disorder. Mol Autism 4: 42.
• 20. Williams BL, Hornig M, Parekh T, et al. (2012) Application of novel PCR-based methods for detection, quantitation, and phylogenetic characterization of Sutterella species in intestinal biopsy samples from children with autism and gastrointestinal disturbances. MBio 3: 54–64.
• 21. Kang DW, Park JG, Ilhan ZE, et al. (2013) Reduced incidence of Prevotella and other fermenters in intestinal microflora of autistic children. PLoS One 8: e68322.    
• 22. Ding HT, Taur Y, Walkup JT (2017) Gut microbiota and autism: Key concepts and findings. J Autism Dev Disord 47: 480–489.    
• 23. Frye RE, Nankova B, Bhattacharyya S, et al. (2017) Modulation of immunological pathways in autistic and neurotypical lymphoblastoid cell lines by the enteric microbiome metabolite propionic acid. Front Immunol 8: 1670.    
• 24. Shaw W (2010) Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutr Neurosci 13: 135–143.
• 25. Wang L, Yu YM, Zhang YQ, et al. (2018) Hydrogen breath test to detect small intestinal bacterial overgrowth: A prevalence case-control study in autism. Eur Child Adolesc Psychiatry 27: 233–240.    
• 26. Adike A, DiBaise JK (2018) Small Intestinal Bacterial Overgrowth: Nutritional Implications, Diagnosis, and Management. Gastroenterol Clin North Am 47: 193–208.    
• 27. House SA, Goodman DC, Weinstein SJ, et al. (2016) Prescription use among children with autism spectrum disorders in Northern New England: Intensity and small area variation. J Pediatr 169: 277–283.    
• 28. Rana SV, Bhardwaj SB (2008) Small intestinal bacterial overgrowth. Scand J Gastroenterol 43: 1030–1037.    
• 29. Quera PR, Quigley EM, Madrid SAM (2005) Small intestinal bacterial overgrowth. An update. Rev Med Chile 133: 1361–1370.
• 30. Gatta L, Scarpignato C (2017) Systematic review with meta-analysis: Rifaximin is effective and safe for the treatment of small intestine bacterial overgrowth. Aliment Pharmacol Ther 45: 604–616.    
• 31. Kwiatkowski L, Rice E, Langland J (2017) Integrative treatment of chronic abdominal bloating and pain associated with overgrowth of small intestinal bacteria: A case report. Altern Ther Health Med 23: 56–61.
• 32. Kernien JF, Snarr BD, Sheppard DC, et al. (2018) The interface between fungal biofilms and innate immunity. Front Immunol 8: 1968.    
• 33. Anwar H, Dasgupta MK, Costerton JW (1990) Testing the susceptibility of bacteria in biofilms to antibacterial agents. Antimicrob Agents Chemother 34: 2043–2046.    
• 34. Høiby N, Bjarnsholt T, Moser C, et al. (2015) ESCMID guideline for the diagnosis and treatment of biofilm infections 2014. Clin Microbiol Infect 1: 1–25.
• 35. Smith A, Buchinsky FJ, Post JC (2011) Eradicating chronic ear, nose, and throat infections: A systematically conducted literature review of advances in biofilm treatment. Otolaryngol Head Neck Surg 144: 338–347.    
• 36. Slobodníková L, Fialová S, Rendeková K, et al. (2016) Antibiofilm activity of plant polyphenols. Molecules 21: 1717.    
• 37. Li XH, Lee JH (2017) Antibiofilm agents: A new perspective for antimicrobial strategy. J Microbiol 55: 753–766.    
• 38. de Magistris L, Familiari V, Pascotto A, et al. (2010) Alterations of the intestinal barrier in patients with autism spectrum disorders and in their first-degree relatives. J Pediatr Gastroenterol Nutr 51: 418–424.    
• 39. Wan MLY, Ling KH, El-Nezami H, et al. (2018) Influence of functional food components on gut health. Crit Rev Food Sci Nutr 2018: 1–10.
• 40. Laparra JM, Sanz Y (2010) Interactions of gut microbiota with functional food components and nutraceuticals. Pharmacol Res 61: 219–225.    

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