Search Advanced

AIMS Medical Science

2019, Volume 6, Issue 3: 210-217. doi: 10.3934/medsci.2019.3.210
Previous Article Next Article
Research article Special Issues

The incidence of pulmonary tuberculosis in patients with anthracosis

  • 1.
    Department of Internal Medicine, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
  • 2.
    Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
  • 3.
    Zoonoses Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran
  • Received: 18 June 2019 Accepted: 10 July 2019 Published: 19 August 2019

  • Background: Anthraco-fibrosis is a potential risk factor for tuberculosis (TB). The aim of this study was to compare the incidence of pulmonary TB in patients with anthracosis and patients without anthracosis. Methods: In this study, all patients who were admitted to the study were selected through enumeration method between 2017 and 2018. Patients with radiological evidence of TB has been considered as suspected of pulmonary TB, and bronchoscopy has been used to detect anthracosis. 40 patients were enrolled as anthracosis patients and 138 as non-anthracosis group. The final diagnosis of active tuberculosis was performed by PCR assay using bronchoalveolar lavage. The data were analyzed by SPSS V.22 using chi-square and logistic regression tests. Results: The incidence of active TB in women and men was 19.3% and 2.1%, respectively (p < 0.001) and the incidence of anthracosis was 28.9% and 16.8% respectively (p = 0.05) which both had a significant difference and were higher in women. Of all patients with anthracosis, 22.5% had active TB. The findings showed that exposure to smoke and anthracosis increases the risk of TB significantly (p < 0.001). Conclusion: The results of this study showed that the patients with anthracosis and those who had long-term exposure to smoke are needed to be evaluated in case of active tuberculosis.

    Citation: Sabah Hasani, Nashmil Andisheh, Shahla Afrasiabian, Anvar Mohammadi. The incidence of pulmonary tuberculosis in patients with anthracosis[J]. AIMS Medical Science, 2019, 6(3): 210-217. doi: 10.3934/medsci.2019.3.210

    Related Papers:

  • Background: Anthraco-fibrosis is a potential risk factor for tuberculosis (TB). The aim of this study was to compare the incidence of pulmonary TB in patients with anthracosis and patients without anthracosis. Methods: In this study, all patients who were admitted to the study were selected through enumeration method between 2017 and 2018. Patients with radiological evidence of TB has been considered as suspected of pulmonary TB, and bronchoscopy has been used to detect anthracosis. 40 patients were enrolled as anthracosis patients and 138 as non-anthracosis group. The final diagnosis of active tuberculosis was performed by PCR assay using bronchoalveolar lavage. The data were analyzed by SPSS V.22 using chi-square and logistic regression tests. Results: The incidence of active TB in women and men was 19.3% and 2.1%, respectively (p < 0.001) and the incidence of anthracosis was 28.9% and 16.8% respectively (p = 0.05) which both had a significant difference and were higher in women. Of all patients with anthracosis, 22.5% had active TB. The findings showed that exposure to smoke and anthracosis increases the risk of TB significantly (p < 0.001). Conclusion: The results of this study showed that the patients with anthracosis and those who had long-term exposure to smoke are needed to be evaluated in case of active tuberculosis.


    加载中

    Acknowledgments


    This article is based on Dr. Nashmil Andisheh's thesis on internal medicine that it has been approved and sponsored by the Vice Chancellor for Research and Technology of Kurdistan University of Medical Sciences [IR.MUK.REC.1396.297]. The authors would like to thank all patients, their family and the staff of the pulmonology clinic of Tohid hospital of Sanandaj for help to perform this study.

    Conflict of interest


    The authors declare no conflict of interest.

    [1] Kasper DL, Fauci AS, Hauser SL, et al. (2018) Harrison's Principles of Internal Medicine, (Vol. 1 & Vol. 2), McGraw Hill Professional.
    [2] Pazoki M, Goodarzi HM, Taheri AH, et al. (2012) Prevalence of tuberculosis in patients with anthracosis: Study on 150 subjects. Arch Iran Med 15: 128.
    [3] Bialvaei AZ, Asgharzadeh M, Aghazadeh M, et al. (2017) Challenges of tuberculosis in Iran. Jundishapur J Microbiol 10.
    [4] Qorbani M, Yunesian M, Baradaran HR (2014) Indoor smoke exposure and risk of anthracosis. Iran J Med Sci 39: 571.
    [5] DEMİRCİ NY, Alici IO, Yilmaz A, et al. (2015) Risk factors and maximum standardized uptake values within lymph nodes of anthracosis diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration. Turk J Med Sci 45: 984–990. doi: 10.3906/sag-1409-99
    [6] Mirsadraee M (2014) Anthracosis of the lungs: etiology, clinical manifestations and diagnosis: a review. Tanaffos 13: 1.
    [7] Uçar EY, Araz Ö, Akgün M, et al. (2014) Bronchial Anthracosis-Anthracofibrosis: Potential Causes and Clinical Characteristics. Eurasian J Pulmonol 16: 17–20. doi: 10.5152/ejp.2014.72681
    [8] Kunal S, Shah A (2017) The concomitant occurrence of pulmonary tuberculosis with bronchial anthracofibrosis. Indian J Tuber 64: 5–9. doi: 10.1016/j.ijtb.2016.10.003
    [9] Rezaeetalab F (2016) Endobronchial tuberculosis in anthracotic bronchitis. Cough 89: 0–01.
    [10] Kim HJ, Kim SD, Shin DW, et al. (2013) Relationship between bronchial anthracofibrosis and endobronchial tuberculosis. Korean J Intern Med 28: 330. doi: 10.3904/kjim.2013.28.3.330
    [11] Gupta A, Shah A (2011) Bronchial anthracofibrosis: an emerging pulmonary disease due to biomass fuel exposure. Int J Tuberc Lung Dis 15: 602–612. doi: 10.5588/ijtld.10.0308
    [12] Pilaniya V, Kunal S, Shah A (2017) Occurrence of bronchial anthracofibrosis in respiratory symptomatics with exposure to biomass fuel smoke. Adv Respir Med 85: 127–135.
    [13] Heidarnazhad H (2012) Anthracosis in Iran, un-answered questions. Arch Iran Med 15: 124.
    [14] Kahkouee S, Pourghorban R, Bitarafan M, (2015) Imaging findings of isolated bronchial anthracofibrosis: A computed tomography analysis of patients with bronchoscopic and histologic confirmation. Arch de Bronconeumología 51: 322–327.
    [15] Fekri MS, Lashkarizadeh MR, Kardoost AH, et al. (2010) Bronchial anthracosis and pulmonary tuberculosis. Tanaffos 9: 21–25.
    [16] Ghanei M, Aslani J, Peyman M, et al. (2011) Bronchial anthracosis: a potent clue for diagnosis of pulmonary tuberculosis. Oman Med J 26: 19. doi: 10.5001/omj.2011.05
    [17] Mireles-Cabodevila E, Karnak D, Shah SS, et al. (2006) Anthracostenosis. J Bronchology Interventional Pulmonol 13: 153–155.
    [18] Kim HY, Im JG, Goo JM, et al. (2000) Bronchial anthracofibrosis (inflammatory bronchial stenosis with anthracotic pigmentation): CT findings. AJR Am J Roentgenol 174: 523–527. doi: 10.2214/ajr.174.2.1740523
    [19] Razi E, Akbari H, Nematollahi L. (2007) Study of Mycobacteria and Mycobacterium Frequency in Patients with Bronchial Anthracofibrosis. J Med Council Iran 26: 346–352.
    [20] Törün T, Güngör G, Özmen I, et al. (2007) Bronchial anthracostenosis in patients exposed to biomass smoke. Turkish Res J 8: 48–51.
    [21] Dennis RJ, Maldonado D, Norman S, et al. (1996) Woodsmoke exposure and risk for obstructive airways disease among women. Chest 109: 115–119. doi: 10.1378/chest.109.1.115
    [22] Sandoval J, Salas J, Martinez-Guerra ML, et al. (1993) Pulmonary arterial hypertension and cor pulmonale associated with chronic domestic woodsmoke inhalation. Chest 103: 12–20. doi: 10.1378/chest.103.1.12
    [23] Park HJ, Park SH, Im SA, et al. (2008) CT differentiation of anthracofibrosis from endobronchial tuberculosis. AJR Am J Roentgenol 191: 247–251. doi: 10.2214/AJR.07.2161
  • Reader Comments
  • © 2019 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
AIMS Medical Science
0.7

Metrics

Article views(2783) PDF downloads(476) Cited by(0)

Preview PDF
Download XML
Export Citation
Article outline

Figures and Tables

Tables(5)

Other Articles By Authors

Related pages

Tools

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog