### Mathematical Biosciences and Engineering

2017, Issue 5&6: 1585-1604. doi: 10.3934/mbe.2017082

# Modeling and analyzing the transmission dynamics of visceral leishmaniasis

• Received: 14 August 2016 Accepted: 27 September 2016 Published: 01 October 2017
• MSC : Primary: 92D25, 92D30; Secondary: 37N25

• In this paper, we develop a mathematical model to study the transmission dynamics of visceral leishmaniasis. Three populations: dogs, sandflies and humans, are considered in the model. Based on recent studies, we include vertical transmission of dogs in the spread of the disease. We also investigate the impact of asymptomatic humans and dogs as secondary reservoirs of the parasites. The basic reproduction number and sensitivity analysis show that the control of dog-sandfly transmission is more important for the elimination of the disease. Vaccination of susceptible dogs, treatment of infective dogs, as well as control of vertical transmission in dogs are effective prevention and control measures for visceral leishmaniasis.

Citation: Lan Zou, Jing Chen, Shigui Ruan. Modeling and analyzing the transmission dynamics of visceral leishmaniasis[J]. Mathematical Biosciences and Engineering, 2017, 14(5&6): 1585-1604. doi: 10.3934/mbe.2017082

### Related Papers:

• In this paper, we develop a mathematical model to study the transmission dynamics of visceral leishmaniasis. Three populations: dogs, sandflies and humans, are considered in the model. Based on recent studies, we include vertical transmission of dogs in the spread of the disease. We also investigate the impact of asymptomatic humans and dogs as secondary reservoirs of the parasites. The basic reproduction number and sensitivity analysis show that the control of dog-sandfly transmission is more important for the elimination of the disease. Vaccination of susceptible dogs, treatment of infective dogs, as well as control of vertical transmission in dogs are effective prevention and control measures for visceral leishmaniasis.
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沈阳化工大学材料科学与工程学院 沈阳 110142

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