Mathematical Biosciences and Engineering, 2012, 9(1): 61-74. doi: 10.3934/mbe.2012.9.61.

Primary: 82C21, 92C35, 74S05; Secondary: 68W40.

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An evaluation of dynamic outlet boundary conditions in a 1D fluid dynamics model

1. Department of Biomedical Engineering, North Carolina State University, Raleigh, NC 27695-7115
2. Department of Biomedical Engineering, Engineering Building 3, RM 4204B, North Carolina State University, Raleigh, NC 27695-7115

When modeling the cardiovascular system, the use of boundary conditions that closely represent the interaction between the region of interest and the surrounding vessels and organs will result in more accurate predictions. An often overlooked feature of outlet boundary conditions is the dynamics associated with regulation of the distribution of pressure and flow. This study implements a dynamic impedance outlet boundary condition in a one-dimensional fluid dynamics model using the pulmonary vasculature and respiration (feedback mechanism) as an example of a dynamic system. The dynamic boundary condition was successfully implemented and the pressure and flow were predicted for an entire respiration cycle. The cardiac cycles at maximal expiration and inspiration were predicted with a root mean square error of $0.61$ and $0.59$ mm Hg, respectively.
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Keywords pulmonary; respiration.; Computational modeling; impedance; structured tree; hemodynamics

Citation: Rachel Clipp, Brooke Steele. An evaluation of dynamic outlet boundary conditions in a 1D fluid dynamics model. Mathematical Biosciences and Engineering, 2012, 9(1): 61-74. doi: 10.3934/mbe.2012.9.61


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  • 2. Tao Du, Dan Hu, David Cai, Timothy W. Secomb, Outflow Boundary Conditions for Blood Flow in Arterial Trees, PLOS ONE, 2015, 10, 5, e0128597, 10.1371/journal.pone.0128597

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