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Effect of blasts on subject-specific computational models of skin and bone sections at various locations on the human body

1 Department of Aerospace Engineering and Mechanics, The University of Alabama, Tuscaloosa AL 35487, USA;
2 School of Chemical Engineering, Mississipi State University, USA

Blast injuries are very common among soldiers deployed in politically unstable regions such as Afghanistan and Iraq, and also in a battle field anywhere in the world. Understanding the mechanics of interaction of blasts with the skin and bone at various parts of the human body is the key to designing effective personal protective equipment (PPE's) which can mitigate blast impacts. In the current work, subject-specific 3D computational models of the skin (with the three layers namely the epidermis, dermis and the hypodermis (muscles)) and bone sections from various parts of the human body (such as the elbow, finger, wrist, cheek bone, forehead, shin etc.) have been developed to study the effect of blast loading. Non-linear material properties have been adopted for the skin and stress impulses at the different skin layers and bone sections are estimated. To date, such an extensive study on the effect of blast loading on the human skin and bone has not been attempted. The results of this study would be indispensable for medical practitioners to understand the effect of blast trauma and plan effective post-traumatic surgical strategies, and also for developing better PPE designs for the military in the future.
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Keywords blast; skin; bone; subject-specific; computational model

Citation: Arnab Chanda, Rebecca Graeter, Vinu Unnikrishnan. Effect of blasts on subject-specific computational models of skin and bone sections at various locations on the human body. AIMS Materials Science, 2015, 2(4): 425-447. doi: 10.3934/matersci.2015.4.425


  • 1. Kulkarni S, Gao X-L, Horner S, et al. (2013) Ballistic helmets-Their design, materials, and performance against traumatic brain injury. Compos Struct 101: 313-331.    
  • 2. Jenson D, Unnikrishnan VU (2015) Energy dissipation of nanocomposite based helmets for blast-induced traumatic brain injury mitigation. Compos Struct 121: 211-216.    
  • 3. Stuhmiller JH, Phillips Y, Richmond D (1991) The physics and mechanisms of primary blast injury. Conventional warfare: ballistic, blast, and burn injuries Washington, DC: Office of the Surgeon General of the US Army, 241-270.
  • 4. Born CT (2004) Blast trauma: the fourth weapon of mass destruction. Scandinavian journal of surgery: SJS: official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 94: 279-285.
  • 5. Chandra N, Ganpule S, Kleinschmit N, et al. (2012) Evolution of blast wave profiles in simulated air blasts: experiment and computational modeling. Shock Waves 22: 403-415.    
  • 6. Chandra N, Skotak M, Wang F, et al. (2013) Do Primary Blast-Shock Waves Cause Mild TBI? Experimental Evidence Based On Animal Models And Human Cadaveric Heads. Mary Ann Liebert, Inc 140 Huguenot Street, 3rd Fl, New Rochelle, NY 10801 USA, A80-A80.
  • 7. Ganpule SG, Chandra N, Salzar R (2013) Mechanics Of Blast Loading On Post-Mortem Human Heads in The Study Of Traumatic Brain Injury (TBI) Using Experimental And Computational Approaches [PhD Dissertation]: University of Nebraska-Lincoln, 289.
  • 8. Ganpule S, Chandra N (2013) Mechanics of Interaction of Blast Waves on Surrogate Head: Effect of Head Orientation. ASME 2013 Summer Bioengineering Conference: American Society of Mechanical Engineers, V01BT55A028-029.
  • 9. Kangarlou K (2013) Mechanics of Blast Loading on the Head Models in the Study of Traumatic Brain Injury. Nationalpark-Forschung In Der Schweiz (Switzerland Research Park Journal), 102.
  • 10. Sundaramurthy A, Alai A, Ganpule S, et al. (2012) Blast-induced biomechanical loading of the rat: an experimental and anatomically accurate computational blast injury model. J Neurotraum 29: 2352-2364.
  • 11. Chafi MS, Ganpule S, Gu L, et al. (2011) Dynamic response of brain subjected to blast loadings: influence of frequency ranges. Int J Appl Mech 3: 803-823.    
  • 12. Ganpule S, Gu L, Alai A, et al. (2012) Role of helmet in the mechanics of shock wave propagation under blast loading conditions. Computer Methods Biomec 15: 1233-1244.
  • 13. Ganpule S, Gu L, Cao G, et al. (2009) The effect of shock wave on a human head. ASME 2009 International Mechanical Engineering Congress and Exposition: American Society of Mechanical Engineers, 339-346.
  • 14. Ganpule S, Gu L, Chandra N (2010) MRI-based three dimensional modeling of blast traumatic brain injury (bTBI). ASME 2010 International Mechanical Engineering Congress and Exposition: American Society of Mechanical Engineers, 181-183.
  • 15. Gu L, Chafi MS, Ganpule S, et al. (2012) The influence of heterogeneous meninges on the brain mechanics under primary blast loading. Compos Part B-Eng 43: 3160-3166.    
  • 16. Gupta RK, Przekwas A (2013) Mathematical models of blast-induced TBI: current status, challenges, and prospects. Front Neurol 4: 59.
  • 17. Hayda R, Harris RM, Bass CD (2004) Blast injury research: modeling injury effects of landmines, bullets, and bombs. Clin Orthop Relate R 422: 97-108.    
  • 18. Jenson D, Unnikrishnan V (2014) Multiscale Simulation of Ballistic Composites for Blast Induced Traumatic Brain Injury Mitigation. ASME 2014 International Mechanical Engineering Congress and Exposition: American Society of Mechanical Engineers. V009T012A072-V009T012A077.
  • 19. Hull J (1992) Traumatic amputation by explosive blast: pattern of injury in survivors. Brit J Surg 79: 1303-1306.
  • 20. DePalma RG, Burris DG, Champion HR, et al. (2005) Blast injuries. New Engl J Med 352: 1335-1342.    
  • 21. Wightman JM, Gladish SL (2001) Explosions and blast injuries. Ann Emerg Med 37: 664-678.    
  • 22. Gondusky JS, Reiter MP (2005) Protecting military convoys in Iraq: an examination of battle injuries sustained by a mechanized battalion during Operation Iraqi Freedom II. Mil Med 170: 546.    
  • 23. Beekley AC, Blackbourne LH, Sebesta JA, et al. (2008) Selective nonoperative management of penetrating torso injury from combat fragmentation wounds. J Trauma Acute Care 64: S108-S117.
  • 24. Xydakis MS, Fravell MD, Nasser KE, et al. (2005) Analysis of battlefield head and neck injuries in Iraq and Afghanistan. Otolaryng Head Neck 133: 497-504.    
  • 25. Breeze J, Allanson-Bailey LS, Hunt NC, et al. (2012) Mortality and morbidity from combat neck injury. J Trauma Acute Care 72: 969-974.    
  • 26. Dussault MC (2013) Blast injury to the human skeleton: recognition, identification and differentiation using morphological and statistical approaches [PhD dissertation]: Bournemouth University, School of Applied Sciences, 350.
  • 27. Bertucci R, Liao J, Williams L (2011) Development of a Lower Extremity Model for Finite Element Analysis at Blast Condition. ASME 2011 Summer Bioengineering Conference: American Society of Mechanical Engineers, 1035-1036.
  • 28. Netter FH (2014) Atlas of human anatomy. Philadelphia, PA: Elsevier Health Sciences.
  • 29. Wolpoff MH, Caspari R (1997) Race and human evolution. New York, NY: Simon and Schuster.
  • 30. Barker DE (1951) Skin thickness in the human. Plast Reconstr Surg 7: 115-116.    
  • 31. Domaracki M, Stephan CN (2006) Facial Soft Tissue Thicknesses in Australian Adult Cadavers*. J Forensic Sci 51: 5-10.    
  • 32. Fields ML, Greenberg BH, Burkett LL (1967) Roentgenographic measurement of skin and heel-pad thickness in the diagnosis of acromegaly. Am J Med Sci 254: 528-533.
  • 33. Garn SM, Haskell JA (1960) Fat thickness and developmental status in childhood and adolescence. AM J Dis Child 99: 746-751.
  • 34. Holbrook KA, Odland GF (1974) Regional differences in the thickness (cell layers) of the human stratum corneum: an ultrastructural analysis. J Invest Dermatol 62: 415-422.    
  • 35. Hwang HS, Park MK, Lee WJ, et al. (2012) Facial soft tissue thickness database for craniofacial reconstruction in Korean adults. J Forensic Sci 57: 1442-1447.    
  • 36. Lee Y, Hwang K (2002) Skin thickness of Korean adults. Surg Radiol Anat 24: 183-189.    
  • 37. Sahni D, Singh G, Jit I, et al. (2008) Facial soft tissue thickness in northwest Indian adults. Forensic Sci Int 176: 137-146.    
  • 38. Simpson E, Henneberg M (2002) Variation in soft tissue thicknesses on the human face and their relation to craniometric dimensions. Am J Phys Anthropol 118: 121-133.    
  • 39. Sipahioğlu S, Ulubay H, Diren HB (2012) Midline facial soft tissue thickness database of Turkish population: MRI study. Forensic Sci Int 219, 1-282: e1-e8.
  • 40. Southwood W (1955) The thickness of the skin. Plast Reconstr Surg 15: 423-429.    
  • 41. Tedeschi-Oliveira SV, Melani RFH, de Almeida NH, et al. (2009) Facial soft tissue thickness of Brazilian adults. Forensic Sci Int 193, 1-127: e1-e7.
  • 42. Whitmore SE, Sago NJG (2000) Caliper-measured skin thickness is similar in white and black women. J Am Acad Dermatol 42: 76-79.    
  • 43. Whitton JT (1973) New values for epidermal thickness and their importance. Health Phys 24: 1-8.    
  • 44. Chanda A, Unnikrishnan V, Roy S, et al. (2015) Computational Modeling of the Female Pelvic Support Structures and Organs to Understand the Mechanism of Pelvic Organ Prolapse: A Review. Appl Mech Rev 67: 040801.    
  • 45. Chanda A, Ghoneim H (2015) Pumping potential of a two-layer left-ventricle-like flexible-matrix-composite structure. Compos Struct 122: 570-575.    
  • 46. Gray H (1918) Anatomy of the human body. Baltimore, MD: Lea & Febiger.
  • 47. Martins P, Natal Jorge R, Ferreira A (2006) A Comparative Study of Several Material Models for Prediction of Hyperelastic Properties: Application to Silicone Rubber and Soft Tissues. Strain 42: 135-147.    
  • 48. Annaidh AN, Bruyère K, Destrade M, et al. (2012) Characterization of the anisotropic mechanical properties of excised human skin. J Mech Behav Biomed 5: 139-148.    
  • 49. Chanda A, Unnikrishnan V, Flynn Z (2015) Biofidelic Human Skin Simulant. US Patent Application No 62/189, 504.
  • 50. Kaster T, Sack I, Samani A (2011) Measurement of the hyperelastic properties of ex vivo brain tissue slices. J Biomech 44: 1158-1163.    
  • 51. O'Hagan JJ, Samani A (2009) Measurement of the hyperelastic properties of 44 pathological ex vivo breast tissue samples. Phys Med Biol 54: 2557.    
  • 52. Flynn CO (2007) The design and validation of a multi-layer model of human skin [PhD Dissertation]. Sligo, Ireland: Institute of Technology, Sligo.
  • 53. Adegbenro A, Taylor S (2013) Structural, Physiological, Functional, and Cultural Differences in Skin of Color. Skin of Color: Springer, 1-19.
  • 54. Saggar S, Wesley NO, Moulton-Levy NM, et al. (2007) Ethnic differences in skin properties: the objective data. Boca Raton, FL: Taylor & Francis.
  • 55. Wesley NO, Maibach HI (2003) Racial (ethnic) differences in skin properties. Am J Clin Dermatol 4: 843-860.    
  • 56. Yosipovitch G, Theng C (2002) Asian skin: its architecture, function and differences from Caucasian skin. Cosmetics Toiletries 117: 57-62.


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Copyright Info: 2015, Vinu Unnikrishnan, et al., licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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