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Determining complex aggregate distributions of macromolecules using photobleaching image correlation microscopy

Centre for Micro-Photonics; Faculty of Science, Engineering and Technology; Swinburne University of Technology; Australia

Special Issues: Cell Surface Receptors

Aggregation of cell surface receptors is believed to be linked to their biological function. In this paper, we disclose the explicit formulation for macromolecular aggregation distribution by means of photobleaching Image Correlation Spectroscopy (pbICS).
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Keywords Photobleaching ICS; Aggregation Distribution; Spatial Autocorrelation

Citation: Alireza Lajevardipour, James W. M. Chon, Andrew H. A. Clayton. Determining complex aggregate distributions of macromolecules using photobleaching image correlation microscopy. AIMS Biophysics, 2015, 2(1): 1-7. doi: 10.3934/biophy.2015.1.1


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  • 1. Andrew H. A. Clayton, , Membrane Organization and Dynamics, 2017, Chapter 5, 91, 10.1007/978-3-319-66601-3_5
  • 2. Andrew H A Clayton, Fluorescence-based approaches for monitoring membrane receptor oligomerization, Journal of Biosciences, 2018, 10.1007/s12038-018-9762-5
  • 3. Laura C. Zanetti-Domingues, Dimitrios Korovesis, Sarah R. Needham, Christopher J. Tynan, Shiori Sagawa, Selene K. Roberts, Antonija Kuzmanic, Elena Ortiz-Zapater, Purvi Jain, Rob C. Roovers, Alireza Lajevardipour, Paul M. P. van Bergen en Henegouwen, George Santis, Andrew H. A. Clayton, David T. Clarke, Francesco L. Gervasio, Yibing Shan, David E. Shaw, Daniel J. Rolfe, Peter J. Parker, Marisa L. Martin-Fernandez, The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers, Nature Communications, 2018, 9, 1, 10.1038/s41467-018-06632-0
  • 4. Chiara Paviolo, James W. M. Chon, Andrew H. A. Clayton, , Biochemical and Biophysical Roles of Cell Surface Molecules, 2018, Chapter 4, 41, 10.1007/978-981-13-3065-0_4

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Copyright Info: 2015, Alireza Lajevardipour, Andrew H. A. Clayton, et al., licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution Licese (http://creativecommons.org/licenses/by/4.0)

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