Review Special Issues

Neglect Dyslexia in Relation to Unilateral Visuospatial Neglect: A Review

  • Received: 30 May 2017 Accepted: 28 July 2017 Published: 12 October 2017
  • Unilateral visuospatial neglect and neglect dyslexia are neuropsychological syndromes in which patients exhibit consistently lateralised perceptual deficits. However, there is little agreement surrounding whether neglect dyslexia is best understood as a consequence of a domain-general visuospatial neglect impairment or as an independent, content-specific cognitive deficit. Previous case studies have revealed that neglect dyslexia is an exceptionally heterogeneous condition and have strongly suggested that not all neglect dyslexia patient error patterns can be fully explained as a consequence of domain-general visuospatial neglect impairment. Additionally, theoretical models which attempt to explain neglect dyslexia as a consequence of domain-general unilateral visuospatial neglect fail to account for neglect dyslexia errors which occur when reading vertically presented words, lack of neglect errors when reading number strings, and neglect dyslexia which co-occurs with oppositely lateralised domain-general visuospatial neglect. Cumulatively, these shortcomings reveal that neglect dyslexia cannot always be accurately characterised as a side-effect of domain-general visuospatial unilateral neglect deficits. These findings strongly imply that neglect dyslexia may be better understood as a content-specific impairment.

    Citation: Margaret Jane Moore, Nele Demeyere. Neglect Dyslexia in Relation to Unilateral Visuospatial Neglect: A Review[J]. AIMS Neuroscience, 2017, 4(4): 148-168. doi: 10.3934/Neuroscience.2017.4.148

    Related Papers:

  • Unilateral visuospatial neglect and neglect dyslexia are neuropsychological syndromes in which patients exhibit consistently lateralised perceptual deficits. However, there is little agreement surrounding whether neglect dyslexia is best understood as a consequence of a domain-general visuospatial neglect impairment or as an independent, content-specific cognitive deficit. Previous case studies have revealed that neglect dyslexia is an exceptionally heterogeneous condition and have strongly suggested that not all neglect dyslexia patient error patterns can be fully explained as a consequence of domain-general visuospatial neglect impairment. Additionally, theoretical models which attempt to explain neglect dyslexia as a consequence of domain-general unilateral visuospatial neglect fail to account for neglect dyslexia errors which occur when reading vertically presented words, lack of neglect errors when reading number strings, and neglect dyslexia which co-occurs with oppositely lateralised domain-general visuospatial neglect. Cumulatively, these shortcomings reveal that neglect dyslexia cannot always be accurately characterised as a side-effect of domain-general visuospatial unilateral neglect deficits. These findings strongly imply that neglect dyslexia may be better understood as a content-specific impairment.



    加载中
    [1] Ellis AW, Young AW (2013) Human Cognitive Neuropsychology: A Textbook With Readings. Psychology Press.
    [2] Linden T, Samuelsson H, Skoog I, et al. (2005) Visual neglect and cognitive impairment in elderly patients late after stroke. Acta Neurologica Scandinavica 111: 163-168.
    [3] Lee BH, Kim EJ, Ku BD, et al. (2008) Cognitive impairments in patients with hemispatial neglect from acute right hemisphere stroke. Cogn Behav Neurol 21: 73-76. doi: 10.1097/WNN.0b013e3181772101
    [4] Lindell AB, Jalas MJ, Tenovuo O, et al. (2007) Clinical assessment of hemispatial neglect: evaluation of different measures and dimensions. Clin Neuropsychol 21: 479-497. doi: 10.1080/13854040600630061
    [5] Heilman KM, Valenstein E (1979) Mechanisms underlying hemispatial neglect. Ann Neurol 5: 166-170. doi: 10.1002/ana.410050210
    [6] Karnath HO, Himmelbach M, Rorden C (2002) The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar. Brain 125: 350-360. doi: 10.1093/brain/awf032
    [7] Ringman JM, Saver JL, Woolson RF, et al. (2004) Frequency, risk factors, anatomy, and course of unilateral neglect in an acute stroke cohort. Neurology 63: 468-474. doi: 10.1212/01.WNL.0000133011.10689.CE
    [8] Stone S, Patel P, Greenwood R, et al. (1992) Measuring visual neglect in acute stroke and predicting its recovery: the visual neglect recovery index. J Neurol Neurosur Ps 55: 431-436. doi: 10.1136/jnnp.55.6.431
    [9] Mort DJ, Malhotra P, Mannan SK, et al. (2003) The anatomy of visual neglect. Brain 126: 1986-1997. doi: 10.1093/brain/awg200
    [10] Chechlacz M, Rotshtein P, Humphreys GW (2012) Neuroanatomical dissections of unilateral visual neglect symptoms: ALE meta-analysis of lesion-symptom mapping. Front Hum Neurosci 6: 230.
    [11] Kleinman JT, Newhart M, Davis C, et al. (2007) Right hemispatial neglect: Frequency and characterization following acute left hemisphere stroke. Brain and Cognition 64: 50-59. doi: 10.1016/j.bandc.2006.10.005
    [12] Suchan J, Rorden C, Karnath HO (2012) Neglect severity after left and right brain damage. Neuropsychologia 50: 1136-1141. doi: 10.1016/j.neuropsychologia.2011.12.018
    [13] Kim EJ, Choi KD, Han MK, et al. (2008) Hemispatial neglect in cerebellar stroke. J Neurol Sci 275: 133-138. doi: 10.1016/j.jns.2008.08.012
    [14] Corbetta M, Shulman GL (2011) Spatial Neglect and Attention Networks. Annu Rev Neurosci 34: 569-599. doi: 10.1146/annurev-neuro-061010-113731
    [15] Mesulam MM (1999) Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events. Philos T R Soc B 354: 1325-1346. doi: 10.1098/rstb.1999.0482
    [16] Kaplan RF, Verfaellie M, Meadows ME, et al. (1991) Changing attentional demands in left hemispatial neglect. JAMA Neurol 48: 1263-1266.
    [17] Kinsbourne M (1993) Unilateral neglect: Clinical and experimental studies. Psychology Press.
    [18] Gauthier L, Dehaut F, Joanette Y (1989) The Bells test: A quantitative and qualitative test for visual neglect. Int J Clin Neuropsychol 11: 49-54.
    [19] Parton A, Malhotra P, Husain M (2004) Hemispatial neglect. J Neurol Neurosur Ps 75: 13-21.
    [20] Halligan PW, Marshall JC (1988) How long is a piece of string? A study of line bisection in a case of visual neglect. Cortex 24: 321-328.
    [21] Kinsella G, Packer S, Ng K, et al. (1995) Continuing issues in the assessment of neglect. Neuropsychological Rehabilitation, 5(3), 239-258.
    [22] Ishiai S, Furukawa T, Tsukagoshi H (1987) Eye-fixation patterns in homonymous hemianopia and unilateral spatial neglect. Neuropsychologia 25: 675-679. doi: 10.1016/0028-3932(87)90058-3
    [23] Zhang X, Kedar S, Lynn M, et al. (2006) Homonymous hemianopia in stroke. J Neuroophthalmol 142: 180-183.
    [24] Cole M, Schutta HS, Warrington EK (1935) Visual disorientation in homonymous half-fields. Brain 12: 257-263.
    [25] Godwin-Austen RB (1965) A case of visual disorientation. J Neurol Neurosur Ps 28: 453-458. doi: 10.1136/jnnp.28.5.453
    [26] Zihl J (1995) Visual scanning behavior in patients with homonymous hemianopia. Neuropsychologia 33: 287-303. doi: 10.1016/0028-3932(94)00119-A
    [27] Chokron S, Colliot P, Bartolomeo P (2004) The role of vision in spatial representation. Cortex 40: 281-290. doi: 10.1016/S0010-9452(08)70123-0
    [28] Heilman K, Watson R (1977) Mechanisms underlying the unilateral neglect syndrome. Adv Neurol 18: 93-106.
    [29] Cocchini G, Cubelli R, Sala SD, et al. (1999) Neglect without extinction. Cortex 35: 285-303. doi: 10.1016/S0010-9452(08)70802-5
    [30] Vossel S, Eschenbeck P, Weiss PH, et al. (2011) Visual extinction in relation to visuospatial neglect after right-hemispheric stroke: quantitative assessment and statistical lesion-symptom mapping. J Neurol Neurosur Ps 82: 862-868. doi: 10.1136/jnnp.2010.224261
    [31] Adair JC, Barrett AM (2010) Spatial neglect: Clinical and neuroscience review. Ann NY Acad Sci 1142: 21-43.
    [32] Driver J, Halligan PW (1991) Can visual neglect operate in object-centred co-ordinates? An affirmative single-case study. Cogn Neuropsychol 8: 475-496.
    [33] Walker R (1995) Spatial and object-based neglect. Neurocase 1: 371-384. doi: 10.1080/13554799508402381
    [34] Ellis AW, Flude BM, Young AW (1987) "Neglect dyslexia" and the early visual processing of letters in words and nonwords. Cogn Neuropsychol 4: 439-464. doi: 10.1080/02643298708252047
    [35] Beschin N, Cubelli R, Della SS, et al. (1997) Left of what? The role of egocentric coordinates in neglect. J Neurol Neurosurg Psychiatry 63: 483-489. doi: 10.1136/jnnp.63.4.483
    [36] Farah MJ, Brunn JL, Wong AB, et al. (1990) Frames of reference for allocating attention to space: Evidence from the neglect syndrome. Neuropsychologia 28: 335. doi: 10.1016/0028-3932(90)90060-2
    [37] Zaehle T, Jordan K, Wüstenberg T, et al. (2007) The neural basis of the egocentric and allocentric spatial frame of reference. Brain Res 1137: 92-103. doi: 10.1016/j.brainres.2006.12.044
    [38] Karnath HO, Rorden C (2012) The anatomy of spatial neglect. Neuropsychologia 50: 1010-1017. doi: 10.1016/j.neuropsychologia.2011.06.027
    [39] Lee B, Suh ME, Seo S, et al. (2009) Neglect dyslexia: Frequency, association with other hemispatial neglects, and lesion localization. Neuropsychologia 47: 704-710. doi: 10.1016/j.neuropsychologia.2008.11.027
    [40] Jackson NE, Coltheart M (2012) Routes To Reading Success and Failure: Toward an Integrated Cognitive Psychology of Atypical Reading. Eur J Cogn Psychol 57: 379-381.
    [41] Riddoch J (1990) Neglect and the peripheral dyslexias. Cogn Neuropsychol 7: 369-389. doi: 10.1080/02643299008253449
    [42] Vallar G, Burani C, Arduino LS (2011) Neglect dyslexia: a review of the neuropsychological literature. Exp Brain Res 208: 311. doi: 10.1007/s00221-010-2527-5
    [43] Leff AP, Spitsyna G, Plant GT, et al. (2006) Structural anatomy of pure and hemianopic alexia. J Neurol Neurosur Ps 77: 1004-1007. doi: 10.1136/jnnp.2005.086983
    [44] Leff A, Starrfelt R (2014) Hemianopic alexia. In: Alexia. London: Springer: 31-69.
    [45] Ptak R, Di Pietro M, Schnider A (2012) The neural correlates of object-centered processing in reading: A lesion study of neglect dyslexia. Neuropsychologia 50: 1142-1150. doi: 10.1016/j.neuropsychologia.2011.09.036
    [46] Mozer MC, Behrmann M (1990) On the interaction of selective attention and lexical knowledge: A connectionist account of neglect dyslexia. J Cognitive Neurosci 2: 96-123. doi: 10.1162/jocn.1990.2.2.96
    [47] Caramazza A, Hillis AE (1990) Spatial representation of words in the brain implied by studies of a unilateral neglect patient. Nature 346: 267-269. doi: 10.1038/346267a0
    [48] Behrmann M, Moscovitch M, Black SE, et al. (1990) Perceptual and conceptual mechanisms in neglect dyslexia: Two contrasting case studies. Brain 113: 1163-1183. doi: 10.1093/brain/113.4.1163
    [49] Savazzi S (2003) Object-based versus object-centred neglect in reading words. Neurocase 9: 203-212. doi: 10.1076/neur.9.3.203.15560
    [50] Riddoch J, Humphreys G, Cleton P, et al. (2007) Interaction of attentional and lexical processes in neglect dyslexia. Cogn Neuropsychol 7: 479-517.
    [51] Nichelli P, Venneri A, Pentore R, et al. (1993) Horizontal and vertical neglect dyslexia. Brain Lang 44: 264-283. doi: 10.1006/brln.1993.1018
    [52] Friedmann N, Nachman-Katz I (2004) Developmental neglect dyslexia in a Hebrew-reading child. Cortex 40: 301-313. doi: 10.1016/S0010-9452(08)70125-4
    [53] Costello AD, Warrington EK (1987) The dissociation of visuospatial neglect and neglect dyslexia. J Neurol Neurosurg Psychiatry 50: 1110-1116. doi: 10.1136/jnnp.50.9.1110
    [54] Cubelli R, Nichelli P, Bonito V, et al. (1991) Different patterns of dissociation in unilateral spatial neglect. Brain Cogn 15: 139-159. doi: 10.1016/0278-2626(91)90023-2
    [55] Katz RB, Sevush S (1989) Positional dyslexia. Brain Lang 37: 266-289. doi: 10.1016/0093-934X(89)90019-9
    [56] Miceli G, Capasso R (2001) Word-centered neglect dyslexia: Evidence from a new case. Neurocase 7: 221-237. doi: 10.1093/neucas/7.3.221
    [57] Fama R, Sullivan EV (2014) Methods of association and dissociation for establishing selective brain-behavior relations. Handb Clin Neurol 125: 175-181. doi: 10.1016/B978-0-444-62619-6.00011-2
    [58] Rorden C, Hjaltason H, Fillmore P, et al. (2012) Allocentric neglect strongly associated with egocentric neglect. Neuropsychologia 50: 1151-1157. doi: 10.1016/j.neuropsychologia.2012.03.031
    [59] Marsh EB, Hillis AE (2008) Dissociation between egocentric and allocentric visuospatial and tactile neglect in acute stroke. Cortex 44: 1215-1220. doi: 10.1016/j.cortex.2006.02.002
    [60] Ota H, Fujii T, Suzuki K, et al. (2001) Dissociation of body-centered and stimulus-centered representations in unilateral neglect. Neurology 57: 2064-2069.
    [61] Beschin N, Cisari C, Cubelli R, et al. (2014) Prose Reading in Neglect. Brain Cogn 84: 69-75. doi: 10.1016/j.bandc.2013.11.002
    [62] Demeyere N, Gillebert C, Loftus L, et al. (2015) Egocentric and allocentric neglect after right and left hemisphere lesions in a large scale neglect study of acute stroke patients: Prevalence and recovery. J Vision 15: 179. doi: 10.1167/15.12.179
    [63] Driver J, Pouget A (2000) Object-centered visual neglect, or relative egocentric neglect? J Cogn Neurosci 12: 542-545.
    [64] Driver J (1999) Object-based and egocentric visual neglect. In The hippocampal and parietal foundations of spatial cognition. Oxford University Press: 67-89.
    [65] Pouget A, Sejnowski TJ (1997) A New View of Hemineglect Based on the Response Properties of Parietal Neurons. Philos Trans R Soc Lond B Biol Sci: 1449-1459.
    [66] Bisiach E, Meregalli S, Berti A (1990) Mechanisms of production control and belief fixation in human visuospatial processing: Clinical evidence from hemispatial nelgect and misrepresentation. In Quantitative analyses of behavior: Computational and clinical approaches to pattern recognition and concept formation. Hillsdale, NJ: Lawrence Erlbaum: 3-21.
    [67] Patterson K, Wilson B (2007) A rose is a rose or a nose: A deficit in initial letter identification. Cogn Neuropsychol 7: 447-477.
    [68] Arduino LS, Daini R, Caterina Silveri M (2005) A stimulus-centered reading disorder for words and numbers: Is it neglect dyslexia? Neurocase 11: 405-415. doi: 10.1080/13554790500263503
    [69] Behrmann M, Black SE, McKeeff TJ, et al. (2002) Oculographic analysis of word reading in hemispatial neglect. Physiol Behav 77: 613-619. doi: 10.1016/S0031-9384(02)00896-X
    [70] Chechlacz M, Novick A, Rotshtein P, et al. (2014) The neural substrates of drawing: a voxel-based morphometry analysis of constructional, hierarchical, and spatial representation deficits. J Cogn Neurosci 26: 2701-2715. doi: 10.1162/jocn_a_00664
    [71] Trojano L, Grossi D, Flash T (2009) Cognitive neuroscience of drawing: Contributions of neuropsychological, experimental and neurofunctional studies. Cortex 45: 269-277. doi: 10.1016/j.cortex.2008.11.015
    [72] Husain M, Kennard C (1997) Distractor-dependent frontal neglect. Neuropsychologia 35: 829-841. doi: 10.1016/S0028-3932(97)00034-1
    [73] Kartsounis LD, Findley LJ (1994) Task specific visuospatial neglect related to density and salience of stimuli. Cortex 30: 647-659. doi: 10.1016/S0010-9452(13)80241-9
    [74] Bonato M, Priftis K, Umiltà C, et al. (2013) Computer-based attention-demanding testing unveils severe neglect in apparently intact patients. Behav Neurol 26: 179-181. doi: 10.1155/2013/139812
    [75] Russell C, Malhotra P, Husain M (2004) Attention modulates the visual field in healthy observers and parietal patients. Neuroreport 15: 2189-2193. doi: 10.1097/00001756-200410050-00009
    [76] Russell C, Malhotra P, Deidda C, et al. (2013) Dynamic attentional modulation of vision across space and time after right hemisphere stroke and in ageing. Cortex 49: 1874-1883. doi: 10.1016/j.cortex.2012.10.005
    [77] Haywood, M., & Coltheart, M (2000) Neglect dyslexia and the early stages of visual word recognition. Neurocase, 6(1), 33-44.
    [78] Reznick J, Friedmann N (2015) Evidence from neglect dyslexia for morphological decomposition at the early stages of orthographic-visual analysis. Front Hum Neurosci 9: 497.
    [79] Hartman-Maeir A, Katz N (1995) Validity of the Behavioral Inattention Test (BIT): relationships with functional tasks. Am J Occup Ther 49: 507-516. doi: 10.5014/ajot.49.6.507
    [80] Demeyere N, Riddoch MJ, Slavkova ED, et al. (2015) The Oxford Cognitive Screen (OCS): Validation of a stroke-specific short cognitive screening tool. Psychol Assess 27: 883-894. doi: 10.1037/pas0000082
    [81] Demeyere N, Riddoch MJ, Slavkova ED, et al. (2016) Domain-specific versus generalized cognitive screening in acute stroke. J Neurol 263: 306-315. doi: 10.1007/s00415-015-7964-4
    [82] Kay J, Lesser R, Coltheart M (1996) Psycholinguistic assessments of language processing in aphasia (PALPA): An introduction. Aphasiology 10: 159-180. doi: 10.1080/02687039608248403
  • Reader Comments
  • © 2017 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0)
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Metrics

Article views(4130) PDF downloads(897) Cited by(7)

Article outline

Figures and Tables

Tables(1)

Other Articles By Authors

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return

Catalog