Special Issue: Recent Advances in the Diagnosis and Treatment of Kawasaki Disease
Guest Editors
Fuyong Jiao
Children's Hospital, Shaanxi Provincial People's Hospital, China
Emali: 3105089948@qq.com
Goerge Chakhunashvili
Tbilisi State Medical University, Tbilisi, Georgia
Emali: euscigeo@yahoo.com
Karim Elakabawi
Cardiovascular Department, Benha University, Benha, Egypt
Emali: karim.hamed@fmed.bu.edu.eg
Manuscript Topics
Kawasaki disease (KD) is an acute, self-limiting vasculitis that predominantly affects children and is a leading cause of acquired heart disease in this population. Since its first description in 1967, the understanding of its etiology and pathophysiology has significantly evolved, yet many aspects of the disease remain unclear. The rapid advancements in genomics, immunology, and imaging technologies over the past decade have provided new insights into the mechanisms underlying Kawasaki disease, from genetic susceptibility to immune dysregulation.
In particular, cutting-edge technologies such as high-throughput sequencing, single-cell RNA sequencing, and advanced imaging techniques have opened up new avenues for early diagnosis and better understanding of disease progression. Furthermore, the use of computational models, machine learning, and artificial intelligence is revolutionizing the prediction of disease outcomes and the development of personalized treatment approaches. Immunomodulatory therapies, including intravenous immunoglobulin (IVIG) and newer biological agents targeting cytokine pathways, are shaping the future of KD treatment, offering the potential for improved patient outcomes and reduced cardiovascular complications.
We invite authors to submit original research and/or review articles focused on the latest technological advancements, pathophysiological mechanisms, diagnostic strategies, and therapeutic interventions in Kawasaki disease. Topics may include novel biomarkers, immune-related pathways, computational models for disease progression, and innovative treatment strategies.
Keywords
Kawasaki Disease
Pediatric Vasculitis
Biomarkers
Immunotherapy
Cardiovascular Complications
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