Manuscript Topics

AIMS Neuroscience invites submissions of manuscripts for a Special Issue on the topic of computational neuroscience. Computational neuroscience includes the modeling and analysis of brain activity across multiple scales of observation. At the lowest level of organization, brain molecular biology analyzes the expression patterns and regulation mechanisms of genes within the developing and adult brain. Molecular biophysics examines the movements and interactions of molecules and ions, resulting in changes in cellular electrical activity. At a higher level of analysis, neuroanatomical patterns of interactions of excitatory and inhibitory inputs result in integration of signals at a cellular level. Further integration of brain regional activity is apparent in the brain regional electroencephalographic and metabolic activity. Computation now plays a major role in all these analyses. The ultimate goal of the Special Issue will be to assess the relationship between brain and neuronal activity models and corresponding experimental results, so both types of submissions are welcome.

Keywords: molecular modeling, neuronal brain activity, connectomics, brain networks, theoretical neuroscience

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