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Special Issue: Current Perspectives on Stress Mechanisms and Mediators in Health and Disease

Guest Editors

Prof. Larry D. Sanford; Prof. Laurie L. Wellman
Sleep Research Laboratory, Center for Integrative Neuroscience and Inflammatory Diseases and Biomedical and Translational Sciences, Macon & Joan Brock Virginia Health Sciences Eastern Virginia Medical School at Old Dominion University
Email: sanforld@ODU.edu; wellmall@ODU.edu

Manuscript Topics

Stress is broadly defined as a nonspecific physiological response to a situation or event that is psychologically and/or physiologically demanding. Classically, the stress response involves activation of the hypothalamo-pituitary-adrenal axis and the autonomic nervous system (sympatho-adrenal branch of the stress system) to initiate and regulate behavioral and physiological adaptations to challenges as well as subsequent restoration of homeostasis. Even though stress can have a significant negative impact on health, stressors are most often encountered without producing persisting or pathological changes and evolving concepts of stress include both beneficial and harmful effects of stressful experiences. Factors that influence whether stress has transitory or lasting effects include characteristics of stressful events including their controllability, predictability, duration, and intensity. Sex and individual resilience and vulnerability are also important in stress outcomes. The effects of stress on the immune system, sleep and arousal, and learning and memory, etc., also can play roles in the long-term impact of a stressful experience. Thus, fully understanding the effects of stress can require studying it in the context of complex interactions between stressor characteristics, sex, individual differences, and other physiological systems that are affected.


This Special Issue welcomes basic and clinical research contributions that address the effects of stress, its modifying factors and interactions with other systems in mediating adaptive and maladaptive/pathological outcomes to challenges. Reviews that address current knowledge or theoretical perspectives in the field are also welcome. Topics covered may include any area examining the physiological and psychological effects of stress and their relevance for health.


Instruction for Authors
http://www.aimspress.com/aimsmeds/news/solo-detail/instructionsforauthors
Please submit your manuscript to online submission system
https://aimspress.jams.pub/

Paper Submission

All manuscripts will be peer-reviewed before their acceptance for publication. The deadline for manuscript submission is 31 May 2026

Published Papers(0)