Order reprints

Dynamical properties and tumor clearance conditions for a nine-dimensional model of bladder cancer immunotherapy

K. E. Starkov Svetlana Bunimovich-Mendrazitsky

*Corresponding author:  


Understanding the global interaction dynamics between tumor and the immunesystem plays a key role in the advancement of cancer therapy.Bunimovich-Mendrazitsky et al. (2015) developed a mathematical model for thestudy of the immune system response to combined therapy for bladder cancerwith Bacillus Calmette-Guérin (BCG) and interleukin-2 (IL-2) . Weutilized a mathematical approach for bladder cancer treatment model forderivation of ultimate upper and lower bounds and proving dissipativityproperty in the sense of Levinson. Furthermore, tumor clearance conditionsfor BCG treatment of bladder cancer are presented. Our method is based onlocalization of compact invariant sets and may be exploited for a predictionof the cells populations dynamics involved into the model.

Please supply your name and a valid email address you yourself

Fields marked*are required

Article URL   http://www.aimspress.com/MBE/article/2247.html
Article ID   1551-0018_2016_5_1059
Editorial Email  
Your Name *
Your Email *
Quantity *

Copyright © AIMS Press All Rights Reserved