Additive Manufacturing: From Medical Applications to Synthetic Biology

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Prof. Andrés Díaz Lantada
Universidad Politécnica de Madrid, Department of Mechanical Engineering, Product Development Laboratory, E-28006 Madrid, Spain.

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Manuscript Topics
Research Interests: Prof. Díaz Lantada is actively researching in different areas related with product development, specially focused on the design of innovative medical devices, by combining rapid prototyping and 3D printing technologies, computer-aided design & engineering tools and active materials for improving diagnostic and therapeutic applications of biodevices. Recently he is aiming at exploring novel ways of interacting at a cellular level with the help of advanced design and manufacturing tools. Currently, he has been UPM Principal Researcher in the EU Project “ToMax: Tool-less manufacture of complex geometries” (Factories of the Future) and UPM Principal Researcher in the EU Project “UBORA: Euro-African Open Biomedical Engineering e-Platform for innovation through Education” (Support to policy and international cooperation).

In the last decades, additive manufacturing technologies have helped to reinvent the way products are developed by enabling the rapid prototyping of concepts and designs and by promoting geometrical complexity and solid freeform fabrication for the integration of advanced functionalities. Such features are very well-suited for the development of innovative biodevices aimed at interacting with living organisms and for supporting bioinspired or biomimetic design strategies based on natural materials and biological systems. Natural geometries, being consequence of resource-limited evolutionary processes amidst challenging environments, are extraordinarily complex and count with a level of integration that cannot be matched with traditional design and manufacturing technologies and synthetic materials.

Recent synergic advances in areas including: Computer-aided design & computational modeling tools, materials science & engineering, information & communication technologies, machine learning, medical imaging and artificial vision technologies, nanotechnology and synthetic biology, among others, have helped to increase the precision and versatility of additive manufacturing technologies, whose industrial impact and scientific-technological potentials in the biomedical field are experimenting an exponential growth. For instance, surgical training & diagnostic models, personalized smart prostheses for soft and hard tissue repair and ad hoc ergonomic appliances are already well-established biomedical applications for enhanced healthcare. The possibility of incorporating living organisms to the material being additively processed (bioprinting) and the advent of multi-material additive manufacturing and 4D printing open new horizons as well, especially for the biomanufacturing of living constructs in personalized medicine, for the development of biohybrid engineering systems and even for working together with Nature towards a better future.

Current Special Issue on “Additive Manufacturing: From Medical Applications to Synthetic Biology” will cover in depth the aforementioned trends. Articles covering the following specific topics are welcome

• Biomedical applications of additive manufacturing (surgical training & planning models, advances diagnostic systems, personalized and smart prostheses, ergonomic aids).
• Bioprinting for tissue engineering & regenerative medicine and for the fabrication of artificial and in vitro organs.
• Design and additive manufacture of advanced microfluidic devices, including labs• & organs-on-chips and humans-on-chips for modeling life and studying disease.
• Design and additive manufacture of personalized medicines and nutrients and related challenges and potentials for a sustainable growth.
• Design and additive manufacture of biohybrid engineering systems and of enhanced synthetic biological systems (i.e. bioprinting with cells, algae, bacteria, among others).
• Collaborative design strategies, innovative partnerships and exemplary educational experiences linked to additive manufacturing technologies in the fields of biomedical engineering, medicine and synthetic biology.

Keywords: Additive Manufacturing; Rapid Prototyping; Biomedical Engineering; Biomimetic Design; 3D & 4D Printing; Bioprinting; Tissue Engineering; Biofabrication; Synthetic Biology; Biohybrid Systems.

Paper submission
Submitted papers should not have been previously published nor be currently under consideration for publication elsewhere. All manuscripts will be peer-reviewed before their acceptance for publication. AIMS Bioengineering charges 300 USD Article Processing Charge (APC) for accepted paper after peer review. AIMS Bioengineering waive the charges for these article types: Review, Editorial, Letter, Conference Reports, Commentary, Corrections, and Erratum.
The deadline for manuscript submission is November 30th, 2018.

Instructions for authors
Please submit your manuscript to online submission system

A. Sydney Gladman, Manuel Garcia-Leiner, Alexis F. Sauer-Budge
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E. Langford, C.A. Griffiths
AIMS Bioengineering, 2018, 5(3): 133-150. doi: 10.3934/bioeng.2018.3.133
+ Abstract     + HTML     + PDF(1199 KB)
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