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Special Issue: Biomedical informatics for clinical applications

Guest Editors

Prof. Buzhou Tang
Harbin Institute of Technology, Shenzhen, China
Email: tangbuzhou@gmail.com


Prof. Tianyong Hao
South China Normal University, Guangzhou, China
Email: haoty@m.scnu.edu.cn


Prof. Zhichang Zhang
Northwest Normal University, Lanzhou, China
Email: zzc@nwnu.edu.cn

Manuscript Topics


With the rapid growth of health and biomedical data, the processing of massive data utilizing advanced information technologies is of great need. Biomedical informatics has widely penetrated various research fields of biomedical science. It plays an increasingly important role in clinical application research, such as disease-related genes discovery, clinical diagnosis, individualized treatment of diseases, the discovery of new drug molecular targets, drug design, etc. The breakthrough progress of biomedical science in the future needs not only the efforts of biologists and physicians but also the intersection and combination of computer science, biology, and medicine. Therefore, this special issue will explore variously structured and unstructured bioinformatics data processing related to biomedical informatics and clinical applications, based on artificial intelligence and related computational techniques, and text mining and natural language processing for biomedical textual data. Relevant topics include, but are not limited to, the following:


• Bioinformatics
• Computational biology
• Health informatics
• Medical informatics
• Evolutionary bioinformatics
• Genome research
• Metagenomic research
• High-throughput sequencing technology
• High-throughput biodata management
• Emerging topics in bioinformatics
• Emerging issues in computational biology
• Drug discovery
• Clinical utility
• Clinical development
• Critical use of clinical information
• Data visualization

Keywords bioinformatics; biomedical science; clinical application; medical informatics.


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Paper Submission

All manuscripts will be peer-reviewed before their acceptance for publication. The deadline for manuscript submission is 31 March 2023

Published Papers(17)

Research article
Predicting the risk of mortality in ICU patients based on dynamic graph attention network of patient similarity
Manfu Ma Penghui Sun Yong Li Weilong Huo
2023, Volume 20, Issue 8: 15326-15344. doi: 10.3934/mbe.2023685
Abstract HTML PDF Cited (3) Viewed (2328)
Research article
Construction of cardiovascular information extraction corpus based on electronic medical records
Hongyang Chang Hongying Zan Shuai Zhang Bingfei Zhao Kunli Zhang
2023, Volume 20, Issue 7: 13379-13397. doi: 10.3934/mbe.2023596
Abstract HTML PDF Cited (2) Viewed (2343)
Research article
Chinese medical event detection based on event frequency distribution ratio and document consistency
Ruirui Han Zhichang Zhang Hao Wei Deyue Yin
2023, Volume 20, Issue 6: 11063-11080. doi: 10.3934/mbe.2023489
Abstract HTML PDF Viewed (2013)
Research article
Automatic detection method of epileptic seizures based on IRCMDE and PSO-SVM
Bei Liu Hongzi Bai Wei Chen Huaquan Chen Zhen Zhang
2023, Volume 20, Issue 5: 9349-9363. doi: 10.3934/mbe.2023410
Abstract HTML PDF Cited (4) Viewed (2160)
Research article
Patient multi-relational graph structure learning for diabetes clinical assistant diagnosis
Yong Li Li Feng
2023, Volume 20, Issue 5: 8428-8445. doi: 10.3934/mbe.2023369
Abstract HTML PDF Cited (4) Viewed (2240)
Research article
Dissection of tumor antigens and immune landscape in clear cell renal cell carcinoma: Preconditions for development and precision medicine of mRNA vaccine
Jianpei Hu Zengnan Mo
2023, Volume 20, Issue 2: 2157-2182. doi: 10.3934/mbe.2023100
Abstract HTML PDF Viewed (3162)
Research article
Hypergraph representation of multimodal brain networks for patients with end-stage renal disease associated with mild cognitive impairment
Zhengtao Xi Tongqiang Liu Haifeng Shi Zhuqing Jiao
2023, Volume 20, Issue 2: 1882-1902. doi: 10.3934/mbe.2023086
Abstract HTML PDF Cited (10) Viewed (2898)
Research article
Disease prediction based on multi-type data fusion from Chinese electronic health record
Zhaoyu Liang Zhichang Zhang Haoyuan Chen Ziqin Zhang
2022, Volume 19, Issue 12: 13732-13746. doi: 10.3934/mbe.2022640
Abstract HTML PDF Cited (5) Viewed (2767)
Research article
Time-sequential graph adversarial learning for brain modularity community detection
Changwei Gong Bing Xue Changhong Jing Chun-Hui He Guo-Cheng Wu Baiying Lei Shuqiang Wang
2022, Volume 19, Issue 12: 13276-13293. doi: 10.3934/mbe.2022621
Abstract HTML PDF Cited (3) Viewed (2731)
Research article
Application of cascade binary pointer tagging in joint entity and relation extraction of Chinese medical text
Hongyang Chang Hongying Zan Tongfeng Guan Kunli Zhang Zhifang Sui
2022, Volume 19, Issue 10: 10656-10672. doi: 10.3934/mbe.2022498
Abstract HTML PDF Cited (11) Viewed (2998)
Research article
Graph-based structural knowledge-aware network for diagnosis assistant
Kunli Zhang Bin Hu Feijie Zhou Yu Song Xu Zhao Xiyang Huang
2022, Volume 19, Issue 10: 10533-10549. doi: 10.3934/mbe.2022492
Abstract HTML PDF Cited (7) Viewed (2783)
Research article
Towards a systematic approach for argumentation, recommendation, and explanation in clinical decision support
Liang Xiao Hao Zhou John Fox
2022, Volume 19, Issue 10: 10445-10473. doi: 10.3934/mbe.2022489
Abstract HTML PDF Cited (2) Viewed (2490)
Research article
Time-of-flight completion in ultrasound computed tomography based on the singular value threshold algorithm
Xiaoyue Fang Ran Zhou Haitao Gan Mingyue Ding Ming Yuchi
2022, Volume 19, Issue 10: 10160-10175. doi: 10.3934/mbe.2022476
Abstract HTML PDF Cited (2) Viewed (2781)
Research article
Spatiotemporal and kinematic characteristics augmentation using Dual-GAN for ankle instability detection
Xin Liu Chen Zhao Bin Zheng Qinwei Guo Yuanyuan Yu Dezheng Zhang Aziguli Wulamu
2022, Volume 19, Issue 10: 10037-10059. doi: 10.3934/mbe.2022469
Abstract HTML PDF Cited (2) Viewed (2551)
Research article
GSTCNet: Gated spatio-temporal correlation network for stroke mortality prediction
Shuo Zhang Yonghao Ren Jing Wang Bo Song Runzhi Li Yuming Xu
2022, Volume 19, Issue 10: 9966-9982. doi: 10.3934/mbe.2022465
Abstract HTML PDF Cited (1) Viewed (2552)
Research article
Double decoupled network for imbalanced obstetric intelligent diagnosis
Kunli Zhang Shuai Zhang Yu Song Linkun Cai Bin Hu
2022, Volume 19, Issue 10: 10006-10021. doi: 10.3934/mbe.2022467
Abstract HTML PDF Cited (1) Viewed (2474)
Research article
Matching biomedical ontologies with GCN-based feature propagation
Peng Wang Shiyi Zou Jiajun Liu Wenjun Ke
2022, Volume 19, Issue 8: 8479-8504. doi: 10.3934/mbe.2022394
Abstract HTML PDF Cited (2) Viewed (2636)