Special Issue: Biomaterial Sciences and Applications
Guest Editors
Prof. Elena IvanovaSchool of Science
Department of Chemistry and Biotechnology, Swinburne University of Technology
Email: eivanova@swin.edu.au
Prof. Russell CrawfordCollege of Science
Engineering and Health, RMIT University, Australia
Email: russell.crawford@rmit.edu.au
Manuscript Topics
Recent advances bio- and nanotechnology have opened a new era for the development of novel biomaterials due to their unique physical, chemical and biological properties.
Implantable materials with a particular surface micro- and/or nanostructure often have the ability to promote human cell attachment and tissue integration; however, these structures can also stimulate the attachment of pathogenic bacteria, which may encounter the substratum prior to, or during surgical processes. If biomaterial device surfaces become infected with pathogenic bacteria, it is likely that the implantation of such devices will result in an infection, requiring their removal before the infection can be effectively treated.
The adaptation of bacteria to survive via the formation of biofilms on conventional surfaces has seen an increase in persistent infections caused by resistant strains of bacteria. Antibiotic resistance presents a worldwide health epidemic that can only be mitigated through the search for a new generation of biomaterials as an alternative to standard methods for the prevention of adhesion and biofilm formation. This search has led to the mimicking of naturally occurring, bacterial resistant or biocidal surfaces via the use of novel nanofabrication methods. The resulting nanostructured surface topographies have been shown to be directly responsible for bacterial inactivation through physico-mechanical means. Plant leaves, insect wings and various animal skins have all been used to inspire the fabrication of synthetic high-aspect ratio nanopillared surfaces that can resist bacterial colonisation.
With the increased use of medical implants with an ageing population, an in-depth investigation into the events taking place at the interface when biomaterials come into contact with biological systems is of considerable importance.
Authors are encouraged to submit an abstract for initial review. The guest editors will then invite a full submission, if appropriate.
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