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AIMS Molecular Science, 2018, 5(2): 166-172. doi: 10.3934/molsci.2018.2.166. Editorial Special Issue

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Autism and neuro-immune-gut link

Dario Siniscalco, Anna Lisa Brigida, Nicola Antonucci

1 Department of Experimental Medicine, University of Campania, 80138 Napoli, Italy
2 Italian Group for Studying Autism – GISA – 25018 Brescia, Italy
3 Biomedical Center for Autism Research and Treatment – 70124 Bari, Italy

Received: , Accepted: , Published:

Special Issue: 2nd European Conference of Biomedical Research and Treatments for Autism

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Recent evidences sustain the hypothesis that host-bacteria interactions play a critical role in regulating tissue and body homeostasis. Gut microbiota and the brain are strongly interconnected and share communication pathways. Modifications in gut bacteria compositions are correlated to changes in behaviors. Indeed, autism spectrum disorders (ASD) are linked to dysfunctions of the gut bacteria-brain axis. Possible therapeutic strategies in ASD management will aim to restore dysbiosis and gut bacteria imbalance.

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Keywords: autism; gut brain axis; intestinal dysfunctions; neuroinflammation

Citation: Dario Siniscalco, Anna Lisa Brigida, Nicola Antonucci. Autism and neuro-immune-gut link. AIMS Molecular Science, 2018, 5(2): 166-172. doi: 10.3934/molsci.2018.2.166

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