Biomechanical and finite element study of drilling sites for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation

Bang Dou; Fangfang Zhang; Ming Ni; Yahui Dai; Zhiyuan Wang; Tao Qin; Wenqian Ma; Wei Zhu; Jiong Mei; Bang Dou; Fangfang Zhang; Ming Ni; Yahui Dai; Zhiyuan Wang; Tao Qin; Wenqian Ma; Wei Zhu; Jiong Mei

doi:10.3934/mbe.2019392

Mathematical Biosciences and Engineering

2019, Volume 16, Issue 6: 7808-7828. doi: 10.3934/mbe.2019392

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Research article

Biomechanical and finite element study of drilling sites for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation

1.
Department of Orthopedics, Songjiang District Central Hospital, Shanghai 201600, China
2.
Department of Orthopedics, Tongji Hospital, Tongji University School of Medicine, Shanghai 200092, China
3.
Department of Orthopedics, Pudong New Area People’s Hospital, Shanghai 201200, China
4.
Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China

Received: 21 March 2019 Accepted: 18 August 2019 Published: 27 August 2019

ObjectiveTo evaluate the influence of drilling sites for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation. MethodsTwelve paired formalin-fixed human cadaveric femora were grouped randomly into 2 groups of 6 pairs each, which were group 1 and group 2, and one of each pair of femora was grouped randomly to drill an oval-shaped hole in the anterior femoral neck, and the contralateral femur was assigned to drill an oval-shaped hole in the lateral of the proximal femur. Group 1 femora were simulated the operation of curettage, bone-grafting and internal fixation, and group 2 femora were simulated the operation of curettage. Besides, finite element models corresponding to mechanical testing were simulated according to one of the twelve femora, then finite element analysis were done. Wilcoxon signed-rank test was used for statistical analysis, with a p value < 0.05 indicating statistical significance. ResultsThe simulated operation of curettage decreased the axial stiffness and torsional stiffness of the intact proximal femur significantly, while there was no statistical difference on the degree of the decline between different drilling sites. Although the simulated operation of bone-grafting and internal fixation in different drilling sites increased the axial stiffness and torsional stiffness, only in the case of implanting bones and internal fixation for the lateral cortical drilled hole increased the axial stiffness greatly and made a statistical difference, even more stiff than the intact proximal femur model. ConclusionCompared with drilling in the anterior femoral neck, a bigger stability could be obtained after drilling in the lateral proximal femur for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation.
- biomechanical,
- finite element analysis,
- drilling site,
- benign lesion,
- femoral head and neck
Citation: Bang Dou, Fangfang Zhang, Ming Ni, Yahui Dai, Zhiyuan Wang, Tao Qin, Wenqian Ma, Wei Zhu, Jiong Mei. Biomechanical and finite element study of drilling sites for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation[J]. Mathematical Biosciences and Engineering, 2019, 16(6): 7808-7828. doi: 10.3934/mbe.2019392

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Abstract

ObjectiveTo evaluate the influence of drilling sites for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation. MethodsTwelve paired formalin-fixed human cadaveric femora were grouped randomly into 2 groups of 6 pairs each, which were group 1 and group 2, and one of each pair of femora was grouped randomly to drill an oval-shaped hole in the anterior femoral neck, and the contralateral femur was assigned to drill an oval-shaped hole in the lateral of the proximal femur. Group 1 femora were simulated the operation of curettage, bone-grafting and internal fixation, and group 2 femora were simulated the operation of curettage. Besides, finite element models corresponding to mechanical testing were simulated according to one of the twelve femora, then finite element analysis were done. Wilcoxon signed-rank test was used for statistical analysis, with a p value < 0.05 indicating statistical significance. ResultsThe simulated operation of curettage decreased the axial stiffness and torsional stiffness of the intact proximal femur significantly, while there was no statistical difference on the degree of the decline between different drilling sites. Although the simulated operation of bone-grafting and internal fixation in different drilling sites increased the axial stiffness and torsional stiffness, only in the case of implanting bones and internal fixation for the lateral cortical drilled hole increased the axial stiffness greatly and made a statistical difference, even more stiff than the intact proximal femur model. ConclusionCompared with drilling in the anterior femoral neck, a bigger stability could be obtained after drilling in the lateral proximal femur for benign lesions in femoral head and neck with curettage, bone-grafting and internal fixation.

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