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Mathematical Biosciences and Engineering

2014, Volume 11, Issue 3: 641-665. doi: 10.3934/mbe.2014.11.641
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Global stability of an age-structured cholera model

  • 1.
    Department of Applied Mathematics, Nanjing University of Science and Technology, Nanjing 210094
  • 2.
    Department of Mathematics, Xinyang Normal University, Xinyang 464000
  • Published: 01 January 2013

  • MSC : Primary: 92B05, 92D30.

  • In this paper, an age-structured epidemicmodel is formulated to describe the transmission dynamics ofcholera. The PDE model incorporates direct and indirect transmissionpathways, infection-age-dependent infectivity and variable periodsof infectiousness. Under some suitable assumptions, the PDE modelcan be reduced to the multi-stage models investigated in theliterature. By using the method of Lyapunov function, we establishedthe dynamical properties of the PDE model, and the results show thatthe global dynamics of the model is completely determined by thebasic reproduction number $\mathcal R_0$: if $\mathcal R_0 < 1$the cholera dies out, and if $\mathcal R_0>1$ the disease will persist at the endemicequilibrium. Then the global results obtained for multi-stage modelsare extended to the general continuous age model.

    Citation: Jianxin Yang, Zhipeng Qiu, Xue-Zhi Li. Global stability of an age-structured cholera model[J]. Mathematical Biosciences and Engineering, 2014, 11(3): 641-665. doi: 10.3934/mbe.2014.11.641

    Related Papers:

  • In this paper, an age-structured epidemicmodel is formulated to describe the transmission dynamics ofcholera. The PDE model incorporates direct and indirect transmissionpathways, infection-age-dependent infectivity and variable periodsof infectiousness. Under some suitable assumptions, the PDE modelcan be reduced to the multi-stage models investigated in theliterature. By using the method of Lyapunov function, we establishedthe dynamical properties of the PDE model, and the results show thatthe global dynamics of the model is completely determined by thebasic reproduction number $\mathcal R_0$: if $\mathcal R_0 < 1$the cholera dies out, and if $\mathcal R_0>1$ the disease will persist at the endemicequilibrium. Then the global results obtained for multi-stage modelsare extended to the general continuous age model.


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