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Designing advanced functional periodic mesoporous organosilicas for biomedical applications

1 Department of Inorganic and Physical Chemistry, Center for Ordered Materials, Organometallics and Catalysis (COMOC), Ghent University, Krijgslaan 281-S3, B-9000 Ghent, Belgium.;
2 Department of Organic Chemistry, Nanochemistry and Fine Chemistry Research Institute(IUIQFN), Faculty of Sciences, University of Córdoba, Campus de Rabanales, Marie Curie Building, Ctra. Nnal. IV, Km 396, 14071 Córdoba, Spain

Special Issues: Materials by Design

Periodic mesoporous organosilicas (PMOs), reported for the first time in 1999, constitute a new branch of organic-inorganic hybrid materials with high-ordered structures, uniform pore size and homogenous distribution of organic bridges into a silica framework. Unlike conventional mesoporous silicas, these materials offer the possibility to adjust the surface (hydrophilicity/hydrophobicity) and physical properties (morphology, porosity) as well as their mechanical stability through the incorporation of different functional organic moieties in their pore walls. A broad variety of PMOs has been designed for their subsequent application in many fields. More recently, PMOs have attracted growing interest in emerging areas as biology and biomedicine. This review provides a comprehensive overview of the most recent breakthroughs achieved for PMOs in biological and biomedical applications.
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Keywords Mesoporous silicas; adsorption; immobilization; enzymes; drug carriers; nanoparticles

Citation: Dolores Esquivel, Pascal Van Der Voort, Francisco J. Romero-Salguero. Designing advanced functional periodic mesoporous organosilicas for biomedical applications. AIMS Materials Science, 2014, 1(1): 70-86. doi: 10.3934/matersci.2014.1.70


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