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Trace metals concentration in vegetables of a sub-urban industrial area of Bangladesh and associated health risk assessment

1 Department of Applied Chemistry and Chemical Engineering, Islamic University, Kushtia 7003, Bangladesh
2 School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia
3 Department of Public Health Engineering, Khulna Zonal Laboratory, Khulna, Bangladesh
Department of Chemical Engineering, School of Engineering, RMIT University (City Campus), Melbourne, Victoria 3001, Australia
5 Department of Soil Science, Patuakhali Science and Technology University, Dumki, Patuakhali-8602, Bangladesh

Trace metals contamination of vegetables in the sub-urban industrial area of Bangladsh are increasing day by day. The mostly consumed vegetables like tomato (Lycopersicon lycopersicum), spinach (Spinacea oleracea), bean (Lablab purpureus), brinjal (Solanum melongena), potato (Solanum tuberosum), cauliflower (Brassica oleracea var botrytis), cabbage (Brassica oleracea var cupitata), and radish (Raphanus sativus) were collected from industrial area. Trace metals arsenic (As), manganese (Mn), zinc (Zn), cadmium (Cd) and lead (Pb) were measured using atomic absorption spectrophotometer (AAS). The descending order of trace metals followed the order of Zn>Mn>Pb>Cd>As. The results revealed that every vegetable contained the highest concentration of Zn range from 15 ± 1.4 to 50 ± 4.0 mg/kg fresh weight. Trace metals in vegetables exceeded the permissible level of FAO and WHO standard. The non-carcinogenic and carcinogenic risks were estimated on the basis of estimated daily intake (EDI), target hazard quotient (THQ), hazard index (HI) and target carcinogenic risks (TRs). The EDI values of all trace metals were below the maximum tolerable daily intake (MTDI). Total target hazard quotient (TTHQ) were greater than 1, indicated that if people consume these types of vegetables in their diet, they might pose risk to these metals. Finally, the total cancer risks (TRs) values were 6.4 × 10−3 for As and 8.7 × 10−5 for Pb which were greater than threshold value of USEPA (10−6), indicating that the consuming inhabitants of these vegetables are exposed to As and Pb with a lifetime cancer risk.
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1. Garg VK, Yadav P, Mor S, et al. (2014) Heavy Metals Bioconcentration from Soil to Vegetables and Assessment of Health Risk Caused by Their Ingestion. Biol Trace Elem Res 157: 256–265.    

2. Cherfi A, Abdoun S, Gaci O (2014) Food survey: levels and potential health risks of chromium, lead, zinc and copper content in fruits and vegetables consumed in Algeria. Food Chem Toxicol 70: 48–53.    

3. Verma P, Agrawal M, Sagar R (2015) Assessment of potential health risks due to heavy metals through vegetable consumption in a tropical area irrigated by treated wastewater. Environ Syst Decis 35: 375–388.    

4. Islam MS, Ahmed MK, Al-Mamun MH, et al. (2014) Preliminary assessment of heavy metal contamination in surface sediments from a river in Bangladesh. Environ Earth Sci 73: 1837–1848.

5. Islam MS, Ahmed MK, Al-Mamun MH, et al. (2014) Trace metals in soil and vegetables and associated health risk assessment. Environ Monitor Assess 186: 8727–8739.    

6. Sharma RK, Agrawal M, Marshall FM (2008) Heavy metal (Cu, Zn, Cd and Pb) contamination of vegetables in urban India: A case study in Varanasi. Environ Poll 154: 254–263.    

7. Islam MS, Ahmed MK, Al-Mamun MH (2015) Metal speciation in soil and health risk due to vegetables consumption in Bangladesh. Environ Monitor Assess 187: 288.    

8. Tchounwou PB, Patlolla AK, Centeno JA (2003) Carcinogenic and systemic health effects associated with arsenic exposure-a critical review. Toxicol Pathol 31: 575–588.

9. Tchounwou PB, Centeno JA, Patlolla AK (2004) Arsenic toxicity, mutagenesis and carcinogenesis-a health risk assessment and management approach. Mole Cell Biochem 255: 47–55.    

10. Kim HS, Kim YJ, Seo YR (2015) An overview of carcinogenic heavy metals: Molecular Toxicity Mechanism and Prevention. J Can Preven 20: 232–240.    

11. USEPA (1999) Integrated Risk Information System (IRIS). National Center for Environmental Assessment, Washington, DC.

12. Itoh H, Iwasaki M, Sawada N, et al. (2014) Dietary cadmium intake and breast cancer risk in Japanese women: a case control study. Intern J Hygi Environ Health 217: 70–77.    

13. Järup L (2003) Hazards of heavy metal contamination. British Med Bullet 68: 167–182.    

14. Jahan S, Khan M, Ahmed S, et al. (2014) Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male rats. Syst Biol Rep Med 60: 28–34.    

15. Yang O, Kim HL, Weon JI, et al. (2015) Endocrine-disrupting chemicals: review of toxicological mechanisms using molecular pathway analysis. J Can Preven 20: 12–24.    

16. Avila DS, Farina M, Rocha JBTda, et al. (2013) Metals, Oxidative stress and neurodegeneration : a focus on iron, manganese and mercury. Neurochem Intern 62: 575–594.    

17. Hambidge KM, Krebs NF (2007) Zinc deficiency: a special challenge. J Nutri 137: 1101–1105.    

18. EPA (2009) Risk assessment guidance for superfund, vol. I: Human health evaluation manual (part F, supplemental guidance for inhalation risk assessment). EPA-540-R-070-002.

19. Shah MT, Shaheen B, Khan S (2010) Pedo and biogeochemical studies of mafic and ultramafic rocks in the Mingora and Kabal areas, Swat, Pakistan. Environ Earth Sci 60: 1091–1102.    

20. Becker W, Jorhem L, Sundström B, et al. (2011) Contents of mineral elements in Swedish market basket diets. J Food Compos Anal 24: 279–287.    

21. Cherfi A, Cherfi M, Maache-Rezzoug Z, et al. (2016) Risk assessment of heavy metals via consumption of vegetables collected from different supermarkets in La Rochelle, France. Environ Monitor Assess 188: 136.    

22. Hu J, Wu F, Wu S, et al. (2013) Bioaccessibility, dietary exposure and human risk assessment of heavy metals from market vegetables in Hong Kong revealed with an in vitro gastrointestinal model. Chemos 91: 455–461.    

23. Song B, Lei M, Chen T, et al. (2009) Assessing the health risk of heavy metals in vegetables to the general population in Beijing, China. J Environ Sci 21: 1702–1709.    

24. Khillare PS, Jyethi DS, Sarkar S (2012) Health risk assessment of polycyclic aromatic hydrocarbons and heavy metals via dietary intake of vegetables grown in the vicinity of thermal power plants. Food Chem Toxicol 50: 1642–1652.    

25. Yang QW, Xu Y, Liu SJ, et al. (2011) Concentration and potential health risk of heavy metals in market vegetables in Chongqing, China. Ecotoxicol Environ Safe 74: 1664–1669.    

26. American Public Health Association (APHA) (2012) Standards Method for for the Examination of Water and Waste Water, 22th edition.

27. Islam MS, Ahmed MK, Raknuzzaman M, et al. (2014) Metal speciation in sediment and their bioaccumulation in fish species of three urban rivers in Bangladesh. Arch Environ Contamin Toxicol 68: 92–106.

28. Household Income and Expenditure Survey (HIES) (2011) Preliminary Report on Household Income and Expenditure Survey-2010. Bangladesh Bureau of Statistics, Statistics Division, Ministry of Planning, Dhaka, Bangladesh.

29. USEPA (2010) Risk-based concentration table. Available from: http://www.epa.gov/reg3hwmd/risk/human/index.html

30. USEPA (1989) Risk assessment guidance for superfund. Human health evaluation manual part A, Interim Final, vol. I. EPA/540/1-89/002. Washington, DC.

31. USEPA (2015) Risk Based Screening Table. Composite Table: Summary Tab 0615. Available from: http:/www2.epa.gov/risk/risk based screening table generic tables.

32. Wang X, Sato T, Xing B, et al. (2005) Health risks of heavy metals to the general public in Tianjin, China via consumption of vegetables and fish. Sci Total Environ 350: 28–37.    

33. Alam MGM, Snow T, Tanaka A (2003) Arsenic and heavy metal contamination of vegetables grown in Samata village, Bangladesh. Sci Total Environ 308: 83–96.    

34. Pandey J, Pandey U (2009) Accumulation of heavy metals in dietary vegetables and cultivated soil horizon in organic farming system in relation to atmospheric deposition in a seasonally dry tropical region of India. Environ Monitor Assess 148: 61–74.    

35. Das HK, Mitra AK, Sengupta PK, et al. (2004) Arsenic concentrations in rice, vegetables, and fish in Bangladesh: a preliminary study. Environ Intern 30: 383–387.    

36. Williams PN, Islam MR, Adomako EE, et al. (2006) Increase in rice grain arsenic for regions of Bangladesh irrigating paddies with elevated arsenic in ground waters. Environ Sci Technol 40: 4903–4908.    

37. Rahman MM, Asaduzzaman M, Naidu R (2013) Consumption of As and other elements from vegetables and drinking water from an As-contaminated area of Bangladesh. J Hazard Mater 262: 1056–1063.    

38. Neumann RB, Ashfaque K, Badruzzaman ABM, et al. (2010) Anthropogenic influences on groundwater arsenic concentrations in Bangladesh. Nat Geo Sci 3: 46–52.    

39. Bhuiyan MAH, Suruvi NI, Dampare SB, et al. (2011) Investigation of the possible sources of heavy metal contamination in lagoon and canal water in the tannery industrial area in Dhaka, Bangladesh. Environ Monitor Assess 175: 633–649.    

40. Bai J, Huang L, Yan D, et al. (2011) Contamination characteristics of heavy metals in wetland soils along a tidal ditch of the Yellow River Estuary, China. Stochastic Environ Res Risk Assess 25: 671–676.    

41. Singh KB, Taneja SK (2010) Concentration of Zn, Cu and Mn in vegetables and meat foodstuffs commonly available in Manipur: a north-eastern state of India. Elect J Environ Agricul Food Chem 9: 610–616.

42. Shaheen N, Irfan NM, Khan IN, et al. (2016) Presence of heavy metals in fruits and vegetables: Health risk implications in Bangladesh. Chemos 152: 431–438.    

43. Roychowdhury T, Tokunaga H, Ando M (2003) Survey of arsenic and other heavy metals in food composites and drinking water and estimation of dietary intake by the villagers from an arsenic-affected area of West Bengal, India. Sci Total Environ 308: 15–35.    

44. Tripathi RM, Raghunath R, Krishnamoorthy TM (1997) Dietaryintake of heavy metals in Bombay city, India. Sci Total Environ 208: 149–159.    

45. Ahmad JU, Goni MA (2010) Heavy metal contamination in water, soil, and vegetables of the industrial areas in Dhaka, Bangladesh. Environ Monitor Assess 166: 347–357.    

46. Khan SI, Ahmed AKM, Yunus M, et al. (2010) Arsenic and cadmium in food chain in Bangladesh-an exploratory study. J Health Popul Nutri 28: 578–584.

47. Islam MS, Ahmed MK, Al-Mamun MH (2015) Determination of heavy metals in fish and vegetables in Bangladesh and health implications. Human Ecol Risk Assess 21: 986–1006.    

48. WHO (World Health Organization) (1985) Guidelines for the Study of Dietary Intakes of Chemical Contaminants. WHO Offset Publication No. 87, Geneva, Switzerland, pp1–100.

49. Agency for Toxic Substances, Disease Registry (ATSDR) (2000) Toxicological, TP-92/02. U.S. Department of Health & Human Services, Atlanta.

50. FAO/WHO (2011) Joint FAO/WHO Food Standards Programme Codex Committee on Contaminants in Foods, Food CF/5 INF/1. Fifth Session. The Hague, the Netherlands.ftp://ftp.fao.org/codex/meeting/CCCF/cccf5/cf05_INF.pdf.

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