Manuscript Topics

Aims Neuroscience is requesting paper submissions for our November issue. Manuscripts will need to be received by January 28, 2015, and decisions on acceptance will be completed by February 28. While research indicates synaptic plasticity is often correlated with acquisition and/or consolidation of new learning and that treatments that interfere with or enhance plasticity interfere with or enhance memory, similar conditions are met by other neural mechanisms not necessarily occurring at synapses, for example alteration of intrinsic excitability of neurons. Problems with synaptic plasticity mechanisms, including odd time courses of events or dissociation from behavioral outcomes, have been explained away via the notion of sparse coding, although experimental evidence for such hidden plasticity is inherently difficult to obtain. Is it time for our field to entertain alternate hypotheses, based upon available experimental data?

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